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Entry version 136 (08 May 2019)
Sequence version 1 (01 Oct 2003)
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Protein

Zinc finger protein 12

Gene

Znf12

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional repressor which suppresses activation protein 1 (AP-1)- and serum response element (SRE)-mediated transcriptional activity.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri263 – 285C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri291 – 313C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri319 – 341C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri347 – 369C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri375 – 397C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri403 – 425C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri431 – 453C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri459 – 481C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri487 – 509C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri515 – 537C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri543 – 565C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri571 – 593C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri599 – 621C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri627 – 649C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri655 – 677C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 12
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Znf12
Synonyms:Zfp12
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:99157 Zfp12

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004028331 – 686Zinc finger protein 12Add BLAST686

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki173Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki203Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki218Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki261Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki303Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki317Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki331Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki359Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki541Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7TSI0

PRoteomics IDEntifications database

More...
PRIDEi
Q7TSI0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7TSI0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7TSI0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000029587 Expressed in 240 organ(s), highest expression level in ear vesicle

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7TSI0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TSI0 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
231183, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000076693

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7TSI0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 79KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri263 – 285C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri291 – 313C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri319 – 341C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri347 – 369C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri375 – 397C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri403 – 425C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri431 – 453C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri459 – 481C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri487 – 509C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri515 – 537C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri543 – 565C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri571 – 593C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri599 – 621C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri627 – 649C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri655 – 677C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154303

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7TSI0

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
PYKWNES

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7TSI0

TreeFam database of animal gene trees

More...
TreeFami
TF350803

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
IPR017455 Znf_FYVE-rel

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 15 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 15 hits
PS50157 ZINC_FINGER_C2H2_2, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7TSI0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNTSLGPLSF KDVAVAFSQE EWQQLDPEER TTYRDVMLET YSNLVSVGYD
60 70 80 90 100
IIKPDVIIKL EQGEEPWIVE GAFSPQSYPD EIRHMSRLME EDQGGEENQS
110 120 130 140 150
SSAVFSYRSR ADASSKATDG ETKPFPSQKA LPQCNSCEKS LMCVSAFIRS
160 170 180 190 200
DGSYAKLRPN VCAGCGKPLP CSKPEETHPG GESYEFSGDG DEDPLGEEGV
210 220 230 240 250
YQKGHFLEEP FEYVECQKSF PKGTVFLNHL EEEPCDWNDA EVAFLQTSDL
260 270 280 290 300
SAHQDSLMEM KPYECQQCGK SFCKKSKFVI HQRTHTGEKP FKCSQCGKSF
310 320 330 340 350
CQKGTLTVHQ RTHTGEKPYE CTECGKTFYQ KLHLIQHQRT HSGEKPYKCG
360 370 380 390 400
YCGKSFCQKT HLTQHQRTHS GERPYVCHDC GKTFSQKSAL NDHQKIHTGV
410 420 430 440 450
KLYKCSECGK CFCRKSTLTT HMRTHTGEKP YECNECGKFF SRLSYLTVHY
460 470 480 490 500
RTHSGEKPYE CAECGKSFYL NSALMRHQRV HTGEKPYECN ECGKLFSQLS
510 520 530 540 550
YLTVHHRTHS GVKPYECSEC GKTFYQNSAL CRHRRIHRGE KPYECYICGK
560 570 580 590 600
FFSQMSYLTI HHRIHSGEKP YECRECGKSF CQNSALNRHQ RTHTGEKAYE
610 620 630 640 650
CYECGKCFSQ MSYLTIHHRI HSGEKPFECN ECGKAFSRMS YLTVHHRTHS
660 670 680
GEKPYECTEC GKKFYHKSAF NSHQRTHRRG SGNGVD
Length:686
Mass (Da):78,617
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA391CBF8D69FE3E4
GO
Isoform 2 (identifier: Q7TSI0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     48-79: Missing.

Show »
Length:654
Mass (Da):75,016
Checksum:i75AB6020EB6C35A8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E0CYZ8E0CYZ8_MOUSE
Zinc finger protein 12
Zfp12
47Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QWS1M0QWS1_MOUSE
Zinc finger protein 12
Zfp12
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04033648 – 79Missing in isoform 2. 1 PublicationAdd BLAST32

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK049650 mRNA Translation: BAC33859.1
CH466529 Genomic DNA Translation: EDL19061.1
CH466529 Genomic DNA Translation: EDL19062.1
BC053080 mRNA Translation: AAH53080.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS19837.1 [Q7TSI0-2]
CCDS71702.1 [Q7TSI0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001276518.1, NM_001289589.1 [Q7TSI0-1]
NP_001276519.1, NM_001289590.1
NP_808349.1, NM_177681.4 [Q7TSI0-2]
XP_017176364.1, XM_017320875.1 [Q7TSI0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000032591; ENSMUSP00000032591; ENSMUSG00000029587 [Q7TSI0-1]
ENSMUST00000077485; ENSMUSP00000076693; ENSMUSG00000029587 [Q7TSI0-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
231866

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:231866

UCSC genome browser

More...
UCSCi
uc009ajt.2 mouse [Q7TSI0-2]
uc009aju.2 mouse [Q7TSI0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK049650 mRNA Translation: BAC33859.1
CH466529 Genomic DNA Translation: EDL19061.1
CH466529 Genomic DNA Translation: EDL19062.1
BC053080 mRNA Translation: AAH53080.1
CCDSiCCDS19837.1 [Q7TSI0-2]
CCDS71702.1 [Q7TSI0-1]
RefSeqiNP_001276518.1, NM_001289589.1 [Q7TSI0-1]
NP_001276519.1, NM_001289590.1
NP_808349.1, NM_177681.4 [Q7TSI0-2]
XP_017176364.1, XM_017320875.1 [Q7TSI0-1]

3D structure databases

SMRiQ7TSI0
ModBaseiSearch...

Protein-protein interaction databases

BioGridi231183, 1 interactor
STRINGi10090.ENSMUSP00000076693

PTM databases

iPTMnetiQ7TSI0
PhosphoSitePlusiQ7TSI0

Proteomic databases

PaxDbiQ7TSI0
PRIDEiQ7TSI0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000032591; ENSMUSP00000032591; ENSMUSG00000029587 [Q7TSI0-1]
ENSMUST00000077485; ENSMUSP00000076693; ENSMUSG00000029587 [Q7TSI0-2]
GeneIDi231866
KEGGimmu:231866
UCSCiuc009ajt.2 mouse [Q7TSI0-2]
uc009aju.2 mouse [Q7TSI0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
231866
MGIiMGI:99157 Zfp12

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000154303
HOGENOMiHOG000234617
InParanoidiQ7TSI0
KOiK09228
OMAiPYKWNES
OrthoDBi1318335at2759
PhylomeDBiQ7TSI0
TreeFamiTF350803

Enzyme and pathway databases

ReactomeiR-MMU-212436 Generic Transcription Pathway

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q7TSI0

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000029587 Expressed in 240 organ(s), highest expression level in ear vesicle
ExpressionAtlasiQ7TSI0 baseline and differential
GenevisibleiQ7TSI0 MM

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
IPR017455 Znf_FYVE-rel
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 15 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 15 hits
PS50157 ZINC_FINGER_C2H2_2, 15 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNF12_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TSI0
Secondary accession number(s): Q8C7Q7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: October 1, 2003
Last modified: May 8, 2019
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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