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Entry version 131 (12 Aug 2020)
Sequence version 1 (01 Oct 2003)
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Protein

Protein PRRC2A

Gene

Prrc2a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in the regulation of pre-mRNA splicing.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • cell differentiation Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein PRRC2A
Alternative name(s):
HLA-B-associated transcript 2
Proline-rich and coiled-coil-containing protein 2A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Prrc2a
Synonyms:Bat2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1915467, Prrc2a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000648311 – 2158Protein PRRC2AAdd BLAST2158

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei18PhosphoserineCombined sources1
Modified residuei19PhosphoserineBy similarity1
Modified residuei27N6-acetyllysineBy similarity1
Modified residuei30PhosphoserineBy similarity1
Modified residuei35N6-acetyllysineCombined sources1
Modified residuei146PhosphoserineBy similarity1
Modified residuei166PhosphoserineCombined sources1
Modified residuei204PhosphoserineBy similarity1
Modified residuei272Asymmetric dimethylarginineBy similarity1
Modified residuei296Omega-N-methylarginineBy similarity1
Modified residuei342PhosphoserineBy similarity1
Modified residuei350PhosphoserineBy similarity1
Modified residuei363PhosphoserineBy similarity1
Modified residuei378PhosphoserineCombined sources1
Modified residuei381PhosphoserineBy similarity1
Modified residuei454PhosphoserineCombined sources1
Modified residuei609PhosphothreonineCombined sources1
Modified residuei759PhosphoserineBy similarity1
Modified residuei761PhosphoserineCombined sources1
Modified residuei764PhosphoserineBy similarity1
Modified residuei807PhosphothreonineCombined sources1
Modified residuei808PhosphoserineCombined sources1
Modified residuei907Omega-N-methylarginineCombined sources1
Modified residuei931PhosphoserineBy similarity1
Modified residuei995PhosphothreonineCombined sources1
Modified residuei1002PhosphoserineBy similarity1
Modified residuei1064Omega-N-methylarginineCombined sources1
Modified residuei1081PhosphothreonineBy similarity1
Modified residuei1083PhosphoserineBy similarity1
Modified residuei1087PhosphoserineCombined sources1
Modified residuei1090PhosphoserineCombined sources1
Modified residuei1092PhosphotyrosineBy similarity1
Modified residuei1104PhosphoserineBy similarity1
Modified residuei1108PhosphoserineBy similarity1
Modified residuei1118PhosphoserineBy similarity1
Modified residuei1145PhosphoserineBy similarity1
Modified residuei1194N6-acetyllysineBy similarity1
Modified residuei1217PhosphoserineCombined sources1
Modified residuei1302PhosphoserineCombined sources1
Modified residuei1306PhosphoserineCombined sources1
Modified residuei1319PhosphothreonineCombined sources1
Modified residuei1321PhosphoserineCombined sources1
Modified residuei1324PhosphoserineBy similarity1
Modified residuei1343PhosphothreonineBy similarity1
Modified residuei1349PhosphothreonineBy similarity1
Modified residuei1380PhosphoserineBy similarity1
Modified residuei1382PhosphoserineBy similarity1
Modified residuei1401PhosphothreonineBy similarity1
Modified residuei1521PhosphoserineBy similarity1
Modified residuei1757PhosphoserineBy similarity1
Modified residuei2037PhosphoserineBy similarity1
Modified residuei2077PhosphothreonineBy similarity1
Modified residuei2114PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7TSC1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7TSC1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7TSC1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7TSC1

PeptideAtlas

More...
PeptideAtlasi
Q7TSC1

PRoteomics IDEntifications database

More...
PRIDEi
Q7TSC1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7TSC1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7TSC1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000024393, Expressed in embryonic post-anal tail and 291 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7TSC1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TSC1, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
207439, 31 interactors

Database of interacting proteins

More...
DIPi
DIP-49629N

Protein interaction database and analysis system

More...
IntActi
Q7TSC1, 7 interactors

Molecular INTeraction database

More...
MINTi
Q7TSC1

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000025253

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7TSC1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7TSC1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati41 – 951-1Add BLAST55
Repeati98 – 1541-2Add BLAST57
Repeati281 – 3361-3Add BLAST56
Repeati337 – 4282-1Add BLAST92
Repeati486 – 5592-2Add BLAST74
Repeati1756 – 18111-4Add BLAST56
Repeati1917 – 19663-1Add BLAST50
Repeati1983 – 20323-2Add BLAST50
Repeati2058 – 21073-3Add BLAST50

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni41 – 18114 X 57 AA type A repeatsAdd BLAST1771
Regioni337 – 5592 X type B repeatsAdd BLAST223
Regioni1917 – 21073 X 50 AA type C repeatsAdd BLAST191

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi401 – 413Poly-ProAdd BLAST13
Compositional biasi464 – 469Poly-Arg6
Compositional biasi470 – 473Poly-Glu4
Compositional biasi657 – 669Poly-GlnAdd BLAST13
Compositional biasi696 – 700Poly-Pro5
Compositional biasi826 – 833Poly-Pro8
Compositional biasi912 – 915Poly-Pro4
Compositional biasi954 – 957Poly-Pro4
Compositional biasi1234 – 1239Poly-Arg6
Compositional biasi1292 – 1295Poly-Pro4
Compositional biasi1409 – 1417Poly-Gly9
Compositional biasi1447 – 1453Poly-Pro7

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4817, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183161

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001247_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7TSC1

Database of Orthologous Groups

More...
OrthoDBi
17901at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7TSC1

TreeFam database of animal gene trees

More...
TreeFami
TF328738

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009738, BAT2_N
IPR033184, PRRC2

The PANTHER Classification System

More...
PANTHERi
PTHR14038, PTHR14038, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07001, BAT2_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q7TSC1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDRSGPTAK GKDGKKYSSL NLFDTYKGKS LEIQKPAVAP RHGLQSLGKV
60 70 80 90 100
AIARRMPPPA NLPSLKAENK GNDPNVSLVP KDGTGWASKQ EQSDPKSSDA
110 120 130 140 150
STAQPPESQP LPASQTPASN QPKRPPTAPE NTPSVPSGVK SWAQASVTHG
160 170 180 190 200
AHGDGGRASN LLSRFSREEF PTLQAAGDQD KAAKERESAE QSSGPGPSLR
210 220 230 240 250
PQNSTTWRDG GGRGPDDLEG PDSKLHHGHD PRGGLQPSGP PQFPPYRGMM
260 270 280 290 300
PPFMYPPYLP FPPPYGPQGP YRYPTPDGPS RFPRVAGPRG SGPPMRLVEP
310 320 330 340 350
VGRPSILKED NLKEFDQLDQ ENDDGWAGAH EEVDYTEKLK FSDEEDGRDS
360 370 380 390 400
DEEGAEGHKD SQSAAAEEPE TDGKKGTSPG SELPPPKTAW TENARPSETE
410 420 430 440 450
PAPPTPKPPP PPPHRGPVGN WGPPGDYPDR GGPPCKPPAP EDEDEAWRQR
460 470 480 490 500
RKQSSSEISL AVERARRRRE EEERRMQEER RAACAEKLKR LDEKFGAPDK
510 520 530 540 550
RLKAEPAAPP VTPAAPALPP VVPKEIPAAP ALPPTPTPTP EKEPEEPAQA
560 570 580 590 600
PPVQAAPSPG VAPVPTLVSG GGCTANSNSS GSFEASPVEP QLPSKEGPEP
610 620 630 640 650
PEEVPPPTTP PAPKMEPKGD GVGSTRQPPS QGLGYPKYQK SLPPRFQRQQ
660 670 680 690 700
QEQLLKQQQQ QQQWQQQQQG TAPPAPVPPS PPQPVTLGAV PAPQAPPPPP
710 720 730 740 750
KALYPGALGR PPPMPPMNFD PRWMMIPPYV DPRLLQGRPP LDFYPPGVHP
760 770 780 790 800
SGLVPRERSD SGGSSSEPFE RHAPPLLRER GTPPVDPKLA WVGDVFTTTP
810 820 830 840 850
TDPRPLTSPL RQAADEEEKS MRSETPPVPP PPPYLANYPG FPENGTPGPP
860 870 880 890 900
ISRFPLEESA PPGPRPLPWP PGNDEAAKMQ APPPKKEPSK EEPPQLSGPE
910 920 930 940 950
AGRKPARGGQ GPPPPRRENR TETRWGPRPG SCRRGIPPEE PGVPPRRAGP
960 970 980 990 1000
IKKPPPPVKV EELPPKSLEQ GDETPKVPKP DALKTAKGKV GPKETPPGGN
1010 1020 1030 1040 1050
LSPAPRLRRD YSYERVGPTS CRGRGRGEYF ARGRGFRGTY GGRGRGARSR
1060 1070 1080 1090 1100
EFRSYREFRG DDGRGGGSGG TNHPSAPRGR TASETRSEGS EYEEIPKRRR
1110 1120 1130 1140 1150
QRGSETGSET HESDLAPSDK EAPPPKEGVL GQVPLAPPQP GAPPSPAPAR
1160 1170 1180 1190 1200
FSTARGGRVF TPRGVPSRRG RGGGRPPPVC SGWSPPAKSL VPKKPPTGPL
1210 1220 1230 1240 1250
PPSKEPLKEK LISGPLSPMS RAGNMGVGME DGERPRRRRH GRAQQQDKPP
1260 1270 1280 1290 1300
RFRRLKQERE NAARGADGKP PSLTLAASTP GPEETLTAAT VPPPPRRTAA
1310 1320 1330 1340 1350
KSPDLSNQNS DQANEEWETA SESSDFASER RGDKETPPAA LMTSKAVGTP
1360 1370 1380 1390 1400
GANAGGAGPG ISAMSRGDLS QRAKDLSKRS FSSQRPGMDR QNRRPGTGGK
1410 1420 1430 1440 1450
TGSGGGSSGG GGAGPGGRTG PGRGDKRSWP SPKNRSRPPE ERPPGLPLPP
1460 1470 1480 1490 1500
PPPSSSAVFR LDQVIHSNPA GIQQALAQLS SRQGNVTAPG GHPRPKPGPP
1510 1520 1530 1540 1550
QAPQGSSPRP PTRYDPPRAS SAISSDPHFE EPGPMVRGVG GTPRDSAGVN
1560 1570 1580 1590 1600
PFPPKRRERP PRKPELLQEE TVPASHSSGF LGSKPEVPGP QEESRDSGTE
1610 1620 1630 1640 1650
ALTPHIWNRL HTATSRKSYQ PGSIEPWMEP LSPFEDVAGT EMSQSDSGVD
1660 1670 1680 1690 1700
LSGDSQVSSG PCSQRSSPDG GLKGSAEGPP KRPGGPSPLN AVPGESASGS
1710 1720 1730 1740 1750
EPSEPPRRRP PASHEGERKE LPREQPLPPG PIGTERSQRT DRGPEPGPLR
1760 1770 1780 1790 1800
PAHRPGSQVE FGTTNKDSDL CLVVGDTLKG EKELVASATE AVPISRDWEL
1810 1820 1830 1840 1850
LPSASTSAEP QPKSLGSGQC VPEPSPSGQR PYPEVFYGSP GPPNSQQVSG
1860 1870 1880 1890 1900
GAPIDSQLHP NSGGFRPGTP SLHQYRSQPL YLPPGPAPPS ALLSGVALKG
1910 1920 1930 1940 1950
QFLDFSALQA TELGKLPAGG VLYPPPSFLY SAAFCPSPLP DPPLLQVRQD
1960 1970 1980 1990 2000
LPSPSDFYST PLQPGGQSGF LPSGAPAQQM LLPVVDSQLP VVNFGSLPPA
2010 2020 2030 2040 2050
PPPAPPPLSL LPVGPALQPP NLAVRPPPAP AARVLPSPAR PFAPSLGRAE
2060 2070 2080 2090 2100
LHPVELKPFQ DYRKLSSNLG GPGSSRTPPS GRPFSGLNSR LKAPPSTYSG
2110 2120 2130 2140 2150
VFRTQRIDLY QQASPPDALR WMPKPWERAG PPSREGPPRR AEEPGSRGEK

EPGLPPPR
Length:2,158
Mass (Da):229,203
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i85A5CBDCDA84A256
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3UX48G3UX48_MOUSE
Protein PRRC2A
Prrc2a
2,069Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1846Missing in AAC82480 (PubMed:14656967).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF109719 Genomic DNA Translation: AAC82480.1
BC006664 mRNA Translation: AAH06664.1
BC053522 mRNA Translation: AAH53522.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37596.1

NCBI Reference Sequences

More...
RefSeqi
NP_001185973.1, NM_001199044.1
NP_064411.2, NM_020027.3
XP_006524683.1, XM_006524620.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000025253; ENSMUSP00000025253; ENSMUSG00000024393

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
53761

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:53761

UCSC genome browser

More...
UCSCi
uc008cgj.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF109719 Genomic DNA Translation: AAC82480.1
BC006664 mRNA Translation: AAH06664.1
BC053522 mRNA Translation: AAH53522.1
CCDSiCCDS37596.1
RefSeqiNP_001185973.1, NM_001199044.1
NP_064411.2, NM_020027.3
XP_006524683.1, XM_006524620.3

3D structure databases

SMRiQ7TSC1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi207439, 31 interactors
DIPiDIP-49629N
IntActiQ7TSC1, 7 interactors
MINTiQ7TSC1
STRINGi10090.ENSMUSP00000025253

PTM databases

iPTMnetiQ7TSC1
PhosphoSitePlusiQ7TSC1

Proteomic databases

EPDiQ7TSC1
jPOSTiQ7TSC1
MaxQBiQ7TSC1
PaxDbiQ7TSC1
PeptideAtlasiQ7TSC1
PRIDEiQ7TSC1

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
62364, 11 antibodies

Genome annotation databases

EnsembliENSMUST00000025253; ENSMUSP00000025253; ENSMUSG00000024393
GeneIDi53761
KEGGimmu:53761
UCSCiuc008cgj.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
7916
MGIiMGI:1915467, Prrc2a

Phylogenomic databases

eggNOGiKOG4817, Eukaryota
GeneTreeiENSGT00950000183161
HOGENOMiCLU_001247_1_0_1
InParanoidiQ7TSC1
OrthoDBi17901at2759
PhylomeDBiQ7TSC1
TreeFamiTF328738

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
53761, 7 hits in 21 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Prrc2a, mouse

Protein Ontology

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PROi
PR:Q7TSC1
RNActiQ7TSC1, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000024393, Expressed in embryonic post-anal tail and 291 other tissues
ExpressionAtlasiQ7TSC1, baseline and differential
GenevisibleiQ7TSC1, MM

Family and domain databases

InterProiView protein in InterPro
IPR009738, BAT2_N
IPR033184, PRRC2
PANTHERiPTHR14038, PTHR14038, 1 hit
PfamiView protein in Pfam
PF07001, BAT2_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPRC2A_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TSC1
Secondary accession number(s): Q923A9, Q9Z1R1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: October 1, 2003
Last modified: August 12, 2020
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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