UniProtKB - Q7TQN6 (Q7TQN6_RAT)
Protein
Submitted name:
G protein-coupled receptor 136
Gene
Opn5
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- 11-cis retinal binding Source: RGD
- G protein-coupled photoreceptor activity Source: RGD
- G protein-coupled receptor activity Source: RGD
GO - Biological processi
- cellular response to light stimulus Source: RGD
- entrainment of circadian clock by photoperiod Source: RGD
- G protein-coupled receptor signaling pathway Source: GO_Central
- hyaloid vascular plexus regression Source: RGD
- phototransduction Source: RGD
- phototransduction, UV Source: RGD
- protein-chromophore linkage Source: UniProtKB-KW
Keywordsi
Molecular function | G-protein coupled receptorUniRule annotation, Photoreceptor protein, Receptor, Retinal proteinARBA annotation, Transducer |
Biological process | |
Ligand | Chromophore |
Enzyme and pathway databases
Reactomei | R-RNO-418594, G alpha (i) signalling events R-RNO-419771, Opsins |
Names & Taxonomyi
Protein namesi | Submitted name: G protein-coupled receptor 136ImportedSubmitted name: Opsin 5Imported |
Gene namesi | |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 727869, Opn5 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 36 – 56 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 77 – 102 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 108 – 129 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 150 – 169 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 198 – 220 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 290 – 314 | HelicalSequence analysisAdd BLAST | 25 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSRNOG00000012689, Expressed in liver and 1 other tissue |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 50 – 343 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 294 |
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG3656, Eukaryota |
GeneTreei | ENSGT01010000222330 |
HOGENOMi | CLU_009579_3_0_1 |
OrthoDBi | 704940at2759 |
TreeFami | TF324998 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR027430, Retinal_BS |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit PS00238, OPSIN, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7TQN6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALNHTALPQ DERLPHYLRD EDPFASKLSW EADLVAGFYL TIIGILSTFG
60 70 80 90 100
NGYVLYMSSR RKKKLRPAEI MTINLAVCDL GISVVGKPFT IISCFCHRWV
110 120 130 140 150
FGWFGCRWYG WAGFFFGCGS LITMTAVSLD RYLKICYLSY GVWLKRKHAY
160 170 180 190 200
ICLAVIWAYA SFWTTMPLVG LGDYAPEPFG TSCTLDWWLA QASGGGQVFI
210 220 230 240 250
LSILFFCLLL PTAVIVFSYA KIIAKVKSSS KEVAHFDSRI HSSHVLEVKL
260 270 280 290 300
TKGLVRADSS PESLPRSVFS TAEPINCHVL SISHSRVSTV AMLICAGFLI
310 320 330 340 350
AWIPYAVVSV WSAFGRPNSI PIQLSVVPTL LAKSAAMYNP IIYQVIDYRF
360 370 380 390 400
ACCQTGGLRA TKKKSLEDFS DLNQILKRNS STKSGQIGNK DTAEEHDRGT
410 420 430 440 450
MQVIGEGEEG TMESTSNSLV PSFHSALKGF HLTQLLANTL SINTSNFRAV
460 470 480 490 500
EKPFLAPRLL SLLLYWDAGE DGLTLADMHL KNVVVLSNRA VPDLLVPMLW
510 520 530
MERVTVMTVT VARNKHLCSE AEKPRSCPSG LQKY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07066882 Genomic DNA No translation available. AY288431 mRNA Translation: AAP72140.1 |
RefSeqi | NP_861437.1, NM_181772.1 |
Genome annotation databases
Ensembli | ENSRNOT00000031759; ENSRNOP00000030570; ENSRNOG00000012689 |
GeneIDi | 316259 |
KEGGi | rno:316259 |
UCSCi | RGD:727869, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07066882 Genomic DNA No translation available. AY288431 mRNA Translation: AAP72140.1 |
RefSeqi | NP_861437.1, NM_181772.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000030570 |
Protein family/group databases
GPCRDBi | Search... |
Proteomic databases
PRIDEi | Q7TQN6 |
Genome annotation databases
Ensembli | ENSRNOT00000031759; ENSRNOP00000030570; ENSRNOG00000012689 |
GeneIDi | 316259 |
KEGGi | rno:316259 |
UCSCi | RGD:727869, rat |
Organism-specific databases
CTDi | 221391 |
RGDi | 727869, Opn5 |
Phylogenomic databases
eggNOGi | KOG3656, Eukaryota |
GeneTreei | ENSGT01010000222330 |
HOGENOMi | CLU_009579_3_0_1 |
OrthoDBi | 704940at2759 |
TreeFami | TF324998 |
Enzyme and pathway databases
Reactomei | R-RNO-418594, G alpha (i) signalling events R-RNO-419771, Opsins |
Gene expression databases
Bgeei | ENSRNOG00000012689, Expressed in liver and 1 other tissue |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR027430, Retinal_BS |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit PS00238, OPSIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q7TQN6_RAT | |
Accessioni | Q7TQN6Primary (citable) accession number: Q7TQN6 Secondary accession number(s): E9PTI9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2003 |
Last sequence update: | October 1, 2003 | |
Last modified: | February 10, 2021 | |
This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |