Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q7TQH7 (LRP10_MOUSE)

Entry version 151 (02 Jun 2021)
Sequence version 2 (27 Jul 2011)
Previous versions | rss
Add a publicationFeedback
Protein

Low-density lipoprotein receptor-related protein 10

Gene

Lrp10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
Biological processEndocytosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-975634, Retinoid metabolism and transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Low-density lipoprotein receptor-related protein 10
Short name:
LRP-10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Lrp10
Synonyms:Lrp9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1929480, Lrp10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini18 – 441ExtracellularSequence analysisAdd BLAST424
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei442 – 462HelicalSequence analysisAdd BLAST21
Topological domaini463 – 713CytoplasmicSequence analysisAdd BLAST251

Keywords - Cellular componenti

Coated pit, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001733618 – 713Low-density lipoprotein receptor-related protein 10Add BLAST696

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi29 ↔ 58By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi57N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi81 ↔ 99By similarity
Glycosylationi112N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi141 ↔ 153By similarity
Disulfide bondi148 ↔ 166By similarity
Disulfide bondi160 ↔ 175By similarity
Disulfide bondi193 ↔ 221By similarity
Glycosylationi194N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi300N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi309 ↔ 332By similarity
Disulfide bondi316 ↔ 345By similarity
Disulfide bondi339 ↔ 354By similarity
Disulfide bondi357 ↔ 375By similarity
Disulfide bondi364 ↔ 388By similarity
Disulfide bondi382 ↔ 397By similarity
Disulfide bondi400 ↔ 412By similarity
Disulfide bondi407 ↔ 425By similarity
Disulfide bondi419 ↔ 434By similarity
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei596PhosphothreonineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q7TQH7

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q7TQH7

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q7TQH7

PRoteomics IDEntifications database

More...PRIDEi		Q7TQH7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		292044

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q7TQH7, 4 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q7TQH7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q7TQH7

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q7TQH7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in heart, lung, liver and liver. Expressed at low level in brain and spleen. Weakly or not expressed in testis and skeletal muscle. In liver, it is expressed in hepatocytes and at higher level in sinusoidal lining. In the kidney, it is expressed in peritubular capillaries. In brain, it is expressed in the epithelium of the choroid plexus ependymal cells of the third ventricle pia matter, and to lesser extent in hippocampal fields CA2 and CA3.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000022175, Expressed in thymus and 326 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q7TQH7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q7TQH7, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000022782

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q7TQH7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q7TQH7

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini29 – 137CUB 1PROSITE-ProRule annotationAdd BLAST109
Domaini140 – 176LDL-receptor class A 1PROSITE-ProRule annotationAdd BLAST37
Domaini193 – 306CUB 2PROSITE-ProRule annotationAdd BLAST114
Domaini308 – 355LDL-receptor class A 2PROSITE-ProRule annotationAdd BLAST48
Domaini356 – 398LDL-receptor class A 3PROSITE-ProRule annotationAdd BLAST43
Domaini399 – 435LDL-receptor class A 4PROSITE-ProRule annotationAdd BLAST37

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni566 – 636DisorderedSequence analysisAdd BLAST71

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi574 – 593Polar residuesSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the LDLR family.Curated

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1215, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000160783

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_013747_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q7TQH7

Identification of Orthologs from Complete Genome Data

More...OMAi		GHFPCGP

Database of Orthologous Groups

More...OrthoDBi		135036at2759

TreeFam database of animal gene trees

More...TreeFami		TF332149

Family and domain databases

Conserved Domains Database

More...CDDi		cd00041, CUB, 2 hits
cd00112, LDLa, 3 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.120.290, 1 hit
4.10.400.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000859, CUB_dom
IPR036055, LDL_receptor-like_sf
IPR023415, LDLR_class-A_CS
IPR002172, LDrepeatLR_classA_rpt
IPR035914, Sperma_CUB_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00431, CUB, 1 hit
PF00057, Ldl_recept_a, 2 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00261, LDLRECEPTOR

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00042, CUB, 2 hits
SM00192, LDLa, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49854, SSF49854, 2 hits
SSF57424, SSF57424, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01180, CUB, 1 hit
PS01209, LDLRA_1, 1 hit
PS50068, LDLRA_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q7TQH7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLSALPLLFL LLGGALARPD RITFPRSACE APPAVLSEVQ GTLQRPLGRD 
        60         70         80         90        100
SRSSPANCTW VILGSKDQTV TVRFQKLHLA CGSEHLILHS PLQPPISLCE 
       110        120        130        140        150
APSGPLQLPG GNVTITYSYA GARAPMGQGF LLTYSQDWLL CLQEEFQCLN 
       160        170        180        190        200
HRCIPAAQRC DGIDACGDGS DEAGCSSDPF PNLNPAPAPT LACNLTLEDF 
       210        220        230        240        250
YGVFSSPGYS HLASVSHPQS CLWLLDPHDG RRLAVRFTAL DLSYGDAVHV 
       260        270        280        290        300
YDGAGPPETP RLLRSLTHFS NGKAVTVETL SGQAVVSYHT VAWSSGRGFN 
       310        320        330        340        350
ATYHVRGYCL PWDRPCGLGS GLGASENLGE RCYSEAQRCD GSWDCADGTD 
       360        370        380        390        400
EEGCPGCPPG HFPCGAAGTP GATACYLPAD RCNYQTFCAD GADERRCRHC 
       410        420        430        440        450
QPGNFRCRDE KCVYETWVCD GQPDCTDGSD EWDCSYALPR KVITAAVIGS 
       460        470        480        490        500
LVCGLLLVIA LGCTCKLYAI RTQEYSIFAP LSRMEAEIVQ QQAPPSYGQL 
       510        520        530        540        550
IAQGAIPPVE DFPTENPNDN SVLGNLRSLL QILRQDMTPG GTSGGRRRQR 
       560        570        580        590        600
GRSIRRLVRR LRRWGLLPRT NTPARAPETR SQVTPSVPSE ALDDSTGQAC 
       610        620        630        640        650
EGGAVGGQDG EQAPPLPIKT PIPTPSTLPA LATVSEPPGP LPSVPVESSL 
       660        670        680        690        700
LSGVVQVLRG RLLPSLWSPG PTWTQTGTHT TVLSPEDEDD VLLLPLAEPE 
       710 
VWVVEAEDEP LLA
Length:713
Mass (Da):76,461
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i27B2B2D44E9AB6E1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3BQ24A0A2I3BQ24_MOUSE
Low-density lipoprotein receptor-re...
Lrp10
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BRF1A0A2I3BRF1_MOUSE
Low-density lipoprotein receptor-re...
Lrp10
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH11058 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti554I → V in BAB20775 (PubMed:11123907).Curated1
Sequence conflicti554I → V in AAH54447 (PubMed:15489334).Curated1
Sequence conflicti598Q → H in BAB20775 (PubMed:11123907).Curated1
Sequence conflicti637P → T in BAB20775 (PubMed:11123907).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB042200 mRNA Translation: BAB20775.1
AK144035 mRNA Translation: BAE25667.1
BC011058 mRNA Translation: AAH11058.1 Different initiation.
BC052378 mRNA Translation: AAH52378.1
BC054447 mRNA Translation: AAH54447.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS27089.1

NCBI Reference Sequences

More...RefSeqi		NP_075369.2, NM_022993.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000022782; ENSMUSP00000022782; ENSMUSG00000022175

Database of genes from NCBI RefSeq genomes

More...GeneIDi		65107

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:65107

UCSC genome browser

More...UCSCi		uc007twd.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB042200 mRNA Translation: BAB20775.1
AK144035 mRNA Translation: BAE25667.1
BC011058 mRNA Translation: AAH11058.1 Different initiation.
BC052378 mRNA Translation: AAH52378.1
BC054447 mRNA Translation: AAH54447.1
CCDSiCCDS27089.1
RefSeqiNP_075369.2, NM_022993.3

3D structure databases

SMRiQ7TQH7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022782

PTM databases

GlyGeniQ7TQH7, 4 sites
iPTMnetiQ7TQH7
PhosphoSitePlusiQ7TQH7
SwissPalmiQ7TQH7

Proteomic databases

EPDiQ7TQH7
MaxQBiQ7TQH7
PaxDbiQ7TQH7
PRIDEiQ7TQH7
ProteomicsDBi292044

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		95, 113 antibodies

The DNASU plasmid repository

More...DNASUi		65107

Genome annotation databases

EnsembliENSMUST00000022782; ENSMUSP00000022782; ENSMUSG00000022175
GeneIDi65107
KEGGimmu:65107
UCSCiuc007twd.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		26020
MGIiMGI:1929480, Lrp10

Phylogenomic databases

eggNOGiKOG1215, Eukaryota
GeneTreeiENSGT00940000160783
HOGENOMiCLU_013747_2_0_1
InParanoidiQ7TQH7
OMAiGHFPCGP
OrthoDBi135036at2759
TreeFamiTF332149

Enzyme and pathway databases

ReactomeiR-MMU-975634, Retinoid metabolism and transport

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		65107, 6 hits in 53 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Lrp10, mouse

Protein Ontology

More...PROi		PR:Q7TQH7
RNActiQ7TQH7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000022175, Expressed in thymus and 326 other tissues
ExpressionAtlasiQ7TQH7, baseline and differential
GenevisibleiQ7TQH7, MM

Family and domain databases

CDDicd00041, CUB, 2 hits
cd00112, LDLa, 3 hits
Gene3Di2.60.120.290, 1 hit
4.10.400.10, 4 hits
InterProiView protein in InterPro
IPR000859, CUB_dom
IPR036055, LDL_receptor-like_sf
IPR023415, LDLR_class-A_CS
IPR002172, LDrepeatLR_classA_rpt
IPR035914, Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00431, CUB, 1 hit
PF00057, Ldl_recept_a, 2 hits
PRINTSiPR00261, LDLRECEPTOR
SMARTiView protein in SMART
SM00042, CUB, 2 hits
SM00192, LDLa, 4 hits
SUPFAMiSSF49854, SSF49854, 2 hits
SSF57424, SSF57424, 2 hits
PROSITEiView protein in PROSITE
PS01180, CUB, 1 hit
PS01209, LDLRA_1, 1 hit
PS50068, LDLRA_2, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLRP10_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TQH7
Secondary accession number(s): Q3UNT0
, Q7TS95, Q921T0, Q9EPE8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: July 27, 2011
Last modified: June 2, 2021
This is version 151 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again