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Protein
Submitted name:

Phospholipase A2, group VI

Gene

Pla2g6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei465NucleophilePROSITE-ProRule annotation1
Active sitei598Proton acceptorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolasePROSITE-ProRule annotation
Biological processLipid degradationPROSITE-ProRule annotation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Phospholipase A2, group VIImported
Gene namesi
Name:Pla2g6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1859152 Pla2g6

Structurei

3D structure databases

ProteinModelPortaliQ7TPX2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini151 – 392ANK_REP_REGIONInterPro annotationAdd BLAST242
Repeati151 – 184ANKPROSITE-ProRule annotationAdd BLAST34
Repeati219 – 251ANKPROSITE-ProRule annotationAdd BLAST33
Repeati316 – 348ANKPROSITE-ProRule annotationAdd BLAST33
Repeati349 – 381ANKPROSITE-ProRule annotationAdd BLAST33
Domaini427 – 611PNPLAInterPro annotationAdd BLAST185

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi431 – 436GXGXXGPROSITE-ProRule annotation6
Motifi463 – 467GXSXGPROSITE-ProRule annotation5
Motifi598 – 600DGA/GPROSITE-ProRule annotation3

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG053482

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR016035 Acyl_Trfase/lysoPLipase
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR002641 PNPLA_dom
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF13606 Ank_3, 1 hit
PF01734 Patatin, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 6 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF52151 SSF52151, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits
PS51635 PNPLA, 1 hit

Sequencei

Sequence statusi: Complete.

Q7TPX2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQFFGRLVNT LSSVTNLFSN PFRVKEVSLT DYVSSERVRE EGQLILLQNV
60 70 80 90 100
SNRTWDCVLV SPRNPQSGFR LFQLESEADA LVNFQQFSSQ LPPFYESSVQ
110 120 130 140 150
VLHVEVLQHL TDLIRNHPSW TVTHLAVELG IRECFHHSRI ISCANSTENE
160 170 180 190 200
EGCTPLHLAC RKGDSEILVE LVQYCHAQMD VTDNKGETAF HYAVQGDNPQ
210 220 230 240 250
VLQLLGKNAS AGLNQVNNQG LTPLHLACKM GKQEMVRVLL LCNARCNIMG
260 270 280 290 300
LGGFPIHTAM KFSQKGCAEM IISMDSNQIH SKDPRYGASP LHWAKNAEMA
310 320 330 340 350
RMLLKRGCDV DSTSSSGNTA LHVAVMRNRF DCVMVLLTYG ANAGARGEHG
360 370 380 390 400
NTPLHLAMSK DNMEMVKALI VFGAEVDTPN DFGETPALIA SKISKQLQDL
410 420 430 440 450
MPISRARKPA FILSSMRDEK RSHDHLLCLD GGGVKGLVII QLLIAIEKAS
460 470 480 490 500
GVATKDLFDW VAGTSTGGIL ALAILHSKSM AYMRGVYFRM KDEVFRGSRP
510 520 530 540 550
YESGPLEEFL KREFGEHTKM TDVKKPKVML TGTLSDRQPA ELHLFRNYDA
560 570 580 590 600
PEAVREPRCN QNINLKPPTQ PADQLVWRAA RSSGAAPTYF RPNGRFLDGG
610 620 630 640 650
LLANNPTLDA MTEIHEYNQD MIRKGQGNKV KKLSIVVSLG TGKSPQVPVT
660 670 680 690 700
CVDVFRPSNP WELAKTVFGA KELGKMVVDC CTDPDGRAVD RARAWCEMVG
710 720 730 740 750
IQYFRLNPQL GSDIMLDEVS DAVLVNALWE TEVYIYEHRE EFQKLVQLLL

SP
Length:752
Mass (Da):83,718
Last modified:October 1, 2003 - v1
Checksum:iDAC3347B0E14AAFC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC052845 mRNA Translation: AAH52845.1
UniGeneiMm.155620

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC052845 mRNA Translation: AAH52845.1
UniGeneiMm.155620

3D structure databases

ProteinModelPortaliQ7TPX2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1859152 Pla2g6

Phylogenomic databases

HOVERGENiHBG053482

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR016035 Acyl_Trfase/lysoPLipase
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR002641 PNPLA_dom
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF13606 Ank_3, 1 hit
PF01734 Patatin, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 6 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF52151 SSF52151, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits
PS51635 PNPLA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ7TPX2_MOUSE
AccessioniPrimary (citable) accession number: Q7TPX2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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