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Protein
Submitted name:

Dystrophin

Gene

Dmd

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
DystrophinImported
Submitted name:
Dystrophin Dp71abImported
Gene namesi
Name:DmdImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi2507 Dmd

PTM / Processingi

Proteomic databases

PRIDEiQ7TPH3

Expressioni

Gene expression databases

BgeeiENSRNOG00000046366 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000032859

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini239 – 286ZZ-typeInterPro annotationAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili415 – 449Sequence analysisAdd BLAST35
Coiled coili488 – 522Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4286 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00760000119237
HOGENOMiHOG000231175
HOVERGENiHBG053790

Family and domain databases

InterProiView protein in InterPro
IPR016344 Dystrophin
IPR011992 EF-hand-dom_pair
IPR015153 EF-hand_dom_typ1
IPR015154 EF-hand_dom_typ2
IPR000433 Znf_ZZ
PANTHERiPTHR44318:SF1 PTHR44318:SF1, 1 hit
PfamiView protein in Pfam
PF09068 EF-hand_2, 1 hit
PF09069 EF-hand_3, 1 hit
PF00569 ZZ, 1 hit
SMARTiView protein in SMART
SM00291 ZnF_ZZ, 1 hit
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS01357 ZF_ZZ_1, 1 hit
PS50135 ZF_ZZ_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.iShow all

Q7TPH3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MREHLKGHET QTTCWDHPKM TELYQSLADL NNVRFSAYRT AMKLRRLQKA
60 70 80 90 100
LCLDLLSLSA ACDALDQHNL KQNDQPMDIL QIINCLTTIY DRLEQEHNNL
110 120 130 140 150
VNVPLCVDMC LNWLLNVYDT GRTGRIRVLS FKTGIISLCK AHLEDKYRYL
160 170 180 190 200
FKQVASSTGF CDQRRLGLLL HDSIQIPRQL GEVASFGGSN IEPSVRSCFQ
210 220 230 240 250
FANNKPEIEA ALFLDWMRLE PQSMVWLPVL HRVAAAETAK HQAKCNICKE
260 270 280 290 300
CPIIGFRYRS LKHFNYDICQ SCFFSGRVAK GHKMHYPMVE YCTPTTSGED
310 320 330 340 350
VRDFAKVLKN KFRTKRYFAK HPRMGYLPVQ TVLEGDNMET PASSPQLSHD
360 370 380 390 400
DTHSRIEHYA SRLAEMENSN GSYLNDSISP NESIDDEHLL IQHYCQSLNQ
410 420 430 440 450
DSPLSQPRSP AQILISLESE ERGELERILA DLEEENRNLQ AEYDRLKQQH
460 470 480 490 500
EHKGLSPLPS PPEMMPTSPQ SPRDAELIAE AKLLRQHKGR LEARMQILED
510 520 530 540 550
HNKQLESQLH RLRQLLEQPQ AEAKVNGTTV SSPSTSLQRS DSSQPMLLRV
560 570 580 590 600
VGSQTSESMG EEDLLSPPQD TSTGLEEVME QLNNSFPSSR GHNVGSLFHM
610 620
ADDLGRAMES LVSVMIDEEG AE
Length:622
Mass (Da):70,785
Last modified:April 1, 2015 - v2
Checksum:i9F67E10D63618053
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P11530DMD_RAT
Dystrophin
Dmd
3,677Annotation score:
Q7TPH4Q7TPH4_RAT
Dystrophin
Dmd
604Annotation score:
Q7TPH2Q7TPH2_RAT
Dystrophin
Dmd
507Annotation score:
D3ZEK8D3ZEK8_RAT
Dystrophin
Dmd
314Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07073532 Genomic DNA No translation available.
AC097383 Genomic DNA No translation available.
AC111223 Genomic DNA No translation available.
AC112800 Genomic DNA No translation available.
AC113761 Genomic DNA No translation available.
AC117871 Genomic DNA No translation available.
AC125680 Genomic DNA No translation available.
AC125768 Genomic DNA No translation available.
AC131219 Genomic DNA No translation available.
AC136037 Genomic DNA No translation available.
AY326948 mRNA Translation: AAP92120.2
RefSeqiNP_001005244.1, NM_001005244.2
UniGeneiRn.10307

Genome annotation databases

EnsembliENSRNOT00000034372; ENSRNOP00000032859; ENSRNOG00000046366
GeneIDi24907
KEGGirno:24907

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07073532 Genomic DNA No translation available.
AC097383 Genomic DNA No translation available.
AC111223 Genomic DNA No translation available.
AC112800 Genomic DNA No translation available.
AC113761 Genomic DNA No translation available.
AC117871 Genomic DNA No translation available.
AC125680 Genomic DNA No translation available.
AC125768 Genomic DNA No translation available.
AC131219 Genomic DNA No translation available.
AC136037 Genomic DNA No translation available.
AY326948 mRNA Translation: AAP92120.2
RefSeqiNP_001005244.1, NM_001005244.2
UniGeneiRn.10307

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000032859

Proteomic databases

PRIDEiQ7TPH3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000034372; ENSRNOP00000032859; ENSRNOG00000046366
GeneIDi24907
KEGGirno:24907

Organism-specific databases

CTDi1756
RGDi2507 Dmd

Phylogenomic databases

eggNOGiKOG4286 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00760000119237
HOGENOMiHOG000231175
HOVERGENiHBG053790

Gene expression databases

BgeeiENSRNOG00000046366 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Family and domain databases

InterProiView protein in InterPro
IPR016344 Dystrophin
IPR011992 EF-hand-dom_pair
IPR015153 EF-hand_dom_typ1
IPR015154 EF-hand_dom_typ2
IPR000433 Znf_ZZ
PANTHERiPTHR44318:SF1 PTHR44318:SF1, 1 hit
PfamiView protein in Pfam
PF09068 EF-hand_2, 1 hit
PF09069 EF-hand_3, 1 hit
PF00569 ZZ, 1 hit
SMARTiView protein in SMART
SM00291 ZnF_ZZ, 1 hit
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS01357 ZF_ZZ_1, 1 hit
PS50135 ZF_ZZ_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ7TPH3_RAT
AccessioniPrimary (citable) accession number: Q7TPH3
Secondary accession number(s): F1LN35
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: April 1, 2015
Last modified: September 12, 2018
This is version 104 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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