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Entry version 123 (12 Aug 2020)
Sequence version 1 (01 Oct 2003)
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Protein

Fatty acyl-CoA reductase 2

Gene

Far2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. A lower activity can be observed with shorter fatty acyl-CoA substrates (PubMed:15220348). It may play a role in the production of ether lipids/plasmalogens and wax monoesters which synthesis requires fatty alcohols as substrates (By similarity).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase
Biological processLipid biosynthesis, Lipid metabolism
LigandNADP

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
1.2.1.50, 3474
1.2.1.84, 3474

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-9640463, Wax biosynthesis

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000000211

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fatty acyl-CoA reductase 21 Publication (EC:1.2.1.841 Publication)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Far2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2687035, Far2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 464CytoplasmicBy similarityAdd BLAST464
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei465 – 484HelicalSequence analysisAdd BLAST20
Topological domaini485 – 515PeroxisomalBy similarityAdd BLAST31

Keywords - Cellular componenti

Membrane, Peroxisome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002614021 – 515Fatty acyl-CoA reductase 2Add BLAST515

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7TNT2

PeptideAtlas

More...
PeptideAtlasi
Q7TNT2

PRoteomics IDEntifications database

More...
PRIDEi
Q7TNT2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7TNT2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7TNT2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Specifically expressed in the meibomian glands of the eyelid and the sebaceous glands of the skin. Also expressed in the brain where large quantities of ether lipids are synthesized.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000030303, Expressed in ear and 168 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TNT2, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000107234

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7TNT2, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the fatty acyl-CoA reductase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1221, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006367

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_024661_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7TNT2

KEGG Orthology (KO)

More...
KOi
K13356

Identification of Orthologs from Complete Genome Data

More...
OMAi
RPFRRPN

Database of Orthologous Groups

More...
OrthoDBi
815047at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7TNT2

TreeFam database of animal gene trees

More...
TreeFami
TF313011

Family and domain databases

Conserved Domains Database

More...
CDDi
cd09071, FAR_C, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026055, FAR
IPR033640, FAR_C
IPR013120, Male_sterile_NAD-bd
IPR036291, NAD(P)-bd_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11011, PTHR11011, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07993, NAD_binding_4, 1 hit
PF03015, Sterile, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51735, SSF51735, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q7TNT2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSMIAAFYSN KSILITGATG FLGKVLMEKL FRTSPHLKVI YILVRPKSGQ
60 70 80 90 100
TLQERVFQIL NSKLFEKVKE VCPNVHEKIR PISADLNQRD FAISKEDVQE
110 120 130 140 150
LLSCTNIIFH CAATVRFDAH LREAVQLNVT ATQQLLLMAS QMPKLEAFIH
160 170 180 190 200
ISTAFSNCNL SHIDEVIYPC PVEPRKIIDS MEWLDDSIIE EITPKLIGDR
210 220 230 240 250
PNTYTYTKAL GEIVVQQESG NLNVAIVRPS IVGATWQEPF PGWVDNLNGP
260 270 280 290 300
SGLIIATGKG FLRSIKATPM AVADVIPVDT VVNLTIAVGW YTAVHRPKST
310 320 330 340 350
LIYHSTSGNL NPCNWYKMGL QVLATIEKIP FESAFRRPNA DFTTSNFTTH
360 370 380 390 400
YWNTVSHRVP AIIYDFYLRL TGRKPRMLKL MNRLLKTISM LEYFINHSWE
410 420 430 440 450
WSTNNTEMLL SELSPEDQRV FNFDVRQLNW LEYIENYVLG VKKYLLKEDL
460 470 480 490 500
AGIPKAKQHL RRLRNIHYLF NTALFLIIWR LLIARSQMAR NVWFFIVSFC
510
YKFISYFRAS STLKV
Length:515
Mass (Da):59,167
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i86CBE93ECC4116C2
GO
Isoform 2 (identifier: Q7TNT2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     497-515: VSFCYKFISYFRASSTLKV → CPLFKL

Show »
Length:502
Mass (Da):57,640
Checksum:i451863259029EE7B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti84A → T in BAC30056 (PubMed:16141072).Curated1
Sequence conflicti194P → H in BAE36237 (PubMed:16141072).Curated1
Sequence conflicti321Q → E in BAE36237 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_021682497 – 515VSFCY…STLKV → CPLFKL in isoform 2. 1 PublicationAdd BLAST19

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK038584 mRNA Translation: BAC30056.1
AK043388 mRNA Translation: BAC31532.1
AK043589 mRNA Translation: BAC31590.1
AK161201 mRNA Translation: BAE36237.1
CU207318 Genomic DNA No translation available.
BC055759 mRNA Translation: AAH55759.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS39718.1 [Q7TNT2-2]
CCDS85188.1 [Q7TNT2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001334445.1, NM_001347516.1 [Q7TNT2-1]
NP_848912.1, NM_178797.3 [Q7TNT2-2]
XP_006507133.1, XM_006507070.3 [Q7TNT2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000032443; ENSMUSP00000032443; ENSMUSG00000030303 [Q7TNT2-1]
ENSMUST00000111607; ENSMUSP00000107234; ENSMUSG00000030303 [Q7TNT2-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
330450

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:330450

UCSC genome browser

More...
UCSCi
uc009etb.1, mouse [Q7TNT2-1]
uc009etc.1, mouse [Q7TNT2-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK038584 mRNA Translation: BAC30056.1
AK043388 mRNA Translation: BAC31532.1
AK043589 mRNA Translation: BAC31590.1
AK161201 mRNA Translation: BAE36237.1
CU207318 Genomic DNA No translation available.
BC055759 mRNA Translation: AAH55759.1
CCDSiCCDS39718.1 [Q7TNT2-2]
CCDS85188.1 [Q7TNT2-1]
RefSeqiNP_001334445.1, NM_001347516.1 [Q7TNT2-1]
NP_848912.1, NM_178797.3 [Q7TNT2-2]
XP_006507133.1, XM_006507070.3 [Q7TNT2-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000107234

Chemistry databases

SwissLipidsiSLP:000000211

PTM databases

iPTMnetiQ7TNT2
PhosphoSitePlusiQ7TNT2

Proteomic databases

PaxDbiQ7TNT2
PeptideAtlasiQ7TNT2
PRIDEiQ7TNT2

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2982, 82 antibodies

Genome annotation databases

EnsembliENSMUST00000032443; ENSMUSP00000032443; ENSMUSG00000030303 [Q7TNT2-1]
ENSMUST00000111607; ENSMUSP00000107234; ENSMUSG00000030303 [Q7TNT2-2]
GeneIDi330450
KEGGimmu:330450
UCSCiuc009etb.1, mouse [Q7TNT2-1]
uc009etc.1, mouse [Q7TNT2-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55711
MGIiMGI:2687035, Far2

Phylogenomic databases

eggNOGiKOG1221, Eukaryota
GeneTreeiENSGT00390000006367
HOGENOMiCLU_024661_0_0_1
InParanoidiQ7TNT2
KOiK13356
OMAiRPFRRPN
OrthoDBi815047at2759
PhylomeDBiQ7TNT2
TreeFamiTF313011

Enzyme and pathway databases

BRENDAi1.2.1.50, 3474
1.2.1.84, 3474
ReactomeiR-MMU-9640463, Wax biosynthesis

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
330450, 2 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Far2, mouse

Protein Ontology

More...
PROi
PR:Q7TNT2
RNActiQ7TNT2, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000030303, Expressed in ear and 168 other tissues
GenevisibleiQ7TNT2, MM

Family and domain databases

CDDicd09071, FAR_C, 1 hit
InterProiView protein in InterPro
IPR026055, FAR
IPR033640, FAR_C
IPR013120, Male_sterile_NAD-bd
IPR036291, NAD(P)-bd_dom_sf
PANTHERiPTHR11011, PTHR11011, 1 hit
PfamiView protein in Pfam
PF07993, NAD_binding_4, 1 hit
PF03015, Sterile, 1 hit
SUPFAMiSSF51735, SSF51735, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFACR2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TNT2
Secondary accession number(s): B2KFC6
, Q3TTT7, Q8BH72, Q8CAK7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: October 1, 2003
Last modified: August 12, 2020
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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