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Entry version 113 (07 Apr 2021)
Sequence version 1 (01 Oct 2003)
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Protein

Dendritic cell-specific transmembrane protein

Gene

Dcstamp

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.9 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Immunity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dendritic cell-specific transmembrane protein
Short name:
DC-STAMP
Short name:
mDC-STAMP
Alternative name(s):
Dendrocyte-expressed seven transmembrane protein
Transmembrane 7 superfamily member 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dcstamp
Synonyms:Tm7sf4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1923016, Dcstamp

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 33CytoplasmicSequence analysisAdd BLAST33
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Topological domaini55ExtracellularSequence analysis1
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Topological domaini77 – 97CytoplasmicSequence analysisAdd BLAST21
Transmembranei98 – 118HelicalSequence analysisAdd BLAST21
Topological domaini119 – 209ExtracellularSequence analysisAdd BLAST91
Transmembranei210 – 230HelicalSequence analysisAdd BLAST21
Topological domaini231 – 292CytoplasmicSequence analysisAdd BLAST62
Transmembranei293 – 313HelicalSequence analysisAdd BLAST21
Topological domaini314 – 376ExtracellularSequence analysisAdd BLAST63
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Topological domaini398 – 470CytoplasmicSequence analysisAdd BLAST73

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Endosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice show a lack of osteoclast and foreign body giant cells multi-nuclear formation and a bone-resorbing efficiency reduction. Mice show increased bone mass. Older (>12 months) mice suffered from multisystemic inflammations in the kidney, lung and salivary gland. Mice show autoimmune symptoms, like dendritic cells (DC) with increased phagocytotic activity and antigen presentation.5 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000725851 – 470Dendritic cell-specific transmembrane proteinAdd BLAST470

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Glycosylated.1 Publication

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7TNJ0

PRoteomics IDEntifications database

More...
PRIDEi
Q7TNJ0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
279891 [Q7TNJ0-1]
279892 [Q7TNJ0-2]
279893 [Q7TNJ0-3]
279894 [Q7TNJ0-4]

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7TNJ0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in macrophages and bone marrow dendritic cells (BM-DC). Weakly expressed in the spleen and lymph node. Highly expressed in multi-nuclear osteoclasts compared to mono-nuclear macrophages. Expressed in foreign body giant cells (FBGCs). Isoform 1 and isoform 2 are expressed in osteoclasts.3 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by IL4/interleukin-4, macrophage colony-stimulating factor (M-CSF), receptor activator of NF-KB ligand (RANKL), lipopolysaccharide (LPS) and toll-like receptor (TLR). Up-regulated by TNFSF11-induced osteoclast differentiation in combination with TNF-alpha. Down-regulated upon dendritic cell (DC) maturation.5 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000022303, Expressed in hindlimb long bone and 39 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7TNJ0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TNJ0, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CREB3 (By similarity). Monomer. Homodimer. Isoform 1 interacts (via the C-terminus cytoplasmic tail) with OS9 isoform 1 (via the C-terminus tail); the interaction induces DCSTAMP redistribution to the endoplasmic reticulum-Golgi intermediate compartment. Isoform 1 interacts (via the C-terminus cytoplasmic tail) with OS9 isoform 2 (via the C-terminus tail).

By similarity1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000022913

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7TNJ0, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Several domains are necessary for interacting with OS9. The region in the cytoplasmic tail that is necessary for interaction with OS9, is also required for its transport.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QWDQ, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153269

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_046145_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7TNJ0

Identification of Orthologs from Complete Genome Data

More...
OMAi
YFTKIHF

Database of Orthologous Groups

More...
OrthoDBi
821078at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7TNJ0

TreeFam database of animal gene trees

More...
TreeFami
TF318254

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012858, DC_STAMP-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07782, DC_STAMP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 11 Publication (identifier: Q7TNJ0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRLWTLGTSI FLRLWGTYVF PRSPSWLDFI QHLGVCCFVA FLSVSLFSAA
60 70 80 90 100
FYWILPPVAL LSSVWMITCV FLCCSKRARC FILLAVLSCG LREGRNALIA
110 120 130 140 150
AGTGVVIFGH VENIFYNFRG LLDSMTCNLR AKSFSVHFPL LKRYTEAIQW
160 170 180 190 200
IYGLATPLNL FDDLVSWNQT LVVSLFSPSH ALEAHMNDTR GEVLGVLHHM
210 220 230 240 250
VVTTELLTSV GQKLLALAGL LLILVSTGLF LKRFLGPCGW KYENVYITKQ
260 270 280 290 300
FVRFDEKERH QQRPCVLPLN KKERKKYVIV PSLQLTPKEK KTLGLFFLPV
310 320 330 340 350
LTYLYMWVLF AAVDYLLYRL ISSMNKQFQS LPGLEVHLKL RGEKQGTQGV
360 370 380 390 400
VHDSAFNISM FEPSCIPKPR LSVSETWVPL SIILLTLIIL GLLSSMLMQL
410 420 430 440 450
KILVSVSFYP KVERERIEYL HAKLLEKRSK QPLREADGKP SLYFKKIHFW
460 470
FPVLKMIRKK QTIPANEDDL
Length:470
Mass (Da):53,876
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9CCFBB82DFC2BE6E
GO
Isoform 21 Publication (identifier: Q7TNJ0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     95-177: Missing.

Show »
Length:387
Mass (Da):44,498
Checksum:i96EEF8ACF1440827
GO
Isoform 31 Publication (identifier: Q7TNJ0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     344-399: Missing.

Show »
Length:414
Mass (Da):47,753
Checksum:i9635B096554688F1
GO
Isoform 41 Publication (identifier: Q7TNJ0-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     344-446: Missing.

Show »
Length:367
Mass (Da):42,138
Checksum:i964ADCF855B82ED1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3BPX1A0A2I3BPX1_MOUSE
Dendritic cell-specific transmembra...
Dcstamp
392Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BRF5A0A2I3BRF5_MOUSE
Dendritic cell-specific transmembra...
Dcstamp
19Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti449F → L in AAR99408 (Ref. 2) Curated1
Sequence conflicti449F → L (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05176395 – 177Missing in isoform 2. 1 PublicationAdd BLAST83
Alternative sequenceiVSP_051764344 – 446Missing in isoform 4. 2 PublicationsAdd BLAST103
Alternative sequenceiVSP_051765344 – 399Missing in isoform 3. 1 PublicationAdd BLAST56

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB109560 mRNA Translation: BAC81438.1
AB109561 mRNA Translation: BAC81439.1
AY517483 mRNA Translation: AAR99406.1
AY517484 mRNA Translation: AAR99407.1
AY517485 mRNA Translation: AAR99408.1
AK014697 mRNA Translation: BAB29508.1
BC139146 mRNA Translation: AAI39147.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS27444.1 [Q7TNJ0-1]
CCDS88758.1 [Q7TNJ0-3]
CCDS88759.1 [Q7TNJ0-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001276437.1, NM_001289508.1 [Q7TNJ0-3]
NP_001276441.1, NM_001289512.1 [Q7TNJ0-4]
NP_083698.1, NM_029422.4 [Q7TNJ0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000022913; ENSMUSP00000022913; ENSMUSG00000022303 [Q7TNJ0-1]
ENSMUST00000227368; ENSMUSP00000154397; ENSMUSG00000022303 [Q7TNJ0-3]
ENSMUST00000228556; ENSMUSP00000154362; ENSMUSG00000022303 [Q7TNJ0-4]

Database of genes from NCBI RefSeq genomes

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GeneIDi
75766

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:75766

UCSC genome browser

More...
UCSCi
uc007voi.2, mouse [Q7TNJ0-1]
uc007voj.2, mouse [Q7TNJ0-4]
uc011zsn.2, mouse [Q7TNJ0-3]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB109560 mRNA Translation: BAC81438.1
AB109561 mRNA Translation: BAC81439.1
AY517483 mRNA Translation: AAR99406.1
AY517484 mRNA Translation: AAR99407.1
AY517485 mRNA Translation: AAR99408.1
AK014697 mRNA Translation: BAB29508.1
BC139146 mRNA Translation: AAI39147.1
CCDSiCCDS27444.1 [Q7TNJ0-1]
CCDS88758.1 [Q7TNJ0-3]
CCDS88759.1 [Q7TNJ0-4]
RefSeqiNP_001276437.1, NM_001289508.1 [Q7TNJ0-3]
NP_001276441.1, NM_001289512.1 [Q7TNJ0-4]
NP_083698.1, NM_029422.4 [Q7TNJ0-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022913

PTM databases

PhosphoSitePlusiQ7TNJ0

Proteomic databases

PaxDbiQ7TNJ0
PRIDEiQ7TNJ0
ProteomicsDBi279891 [Q7TNJ0-1]
279892 [Q7TNJ0-2]
279893 [Q7TNJ0-3]
279894 [Q7TNJ0-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
42882, 82 antibodies

Genome annotation databases

EnsembliENSMUST00000022913; ENSMUSP00000022913; ENSMUSG00000022303 [Q7TNJ0-1]
ENSMUST00000227368; ENSMUSP00000154397; ENSMUSG00000022303 [Q7TNJ0-3]
ENSMUST00000228556; ENSMUSP00000154362; ENSMUSG00000022303 [Q7TNJ0-4]
GeneIDi75766
KEGGimmu:75766
UCSCiuc007voi.2, mouse [Q7TNJ0-1]
uc007voj.2, mouse [Q7TNJ0-4]
uc011zsn.2, mouse [Q7TNJ0-3]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
81501
MGIiMGI:1923016, Dcstamp

Phylogenomic databases

eggNOGiENOG502QWDQ, Eukaryota
GeneTreeiENSGT00940000153269
HOGENOMiCLU_046145_0_0_1
InParanoidiQ7TNJ0
OMAiYFTKIHF
OrthoDBi821078at2759
PhylomeDBiQ7TNJ0
TreeFamiTF318254

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
75766, 0 hits in 52 CRISPR screens

Protein Ontology

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PROi
PR:Q7TNJ0
RNActiQ7TNJ0, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000022303, Expressed in hindlimb long bone and 39 other tissues
ExpressionAtlasiQ7TNJ0, baseline and differential
GenevisibleiQ7TNJ0, MM

Family and domain databases

InterProiView protein in InterPro
IPR012858, DC_STAMP-like
PfamiView protein in Pfam
PF07782, DC_STAMP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDCSTP_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TNJ0
Secondary accession number(s): B2RT61
, Q6R315, Q7TNI9, Q9D619
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: October 1, 2003
Last modified: April 7, 2021
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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