UniProtKB - Q7TNE3 (SPAG7_MOUSE)
Protein
Sperm-associated antigen 7
Gene
Spag7
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Sperm-associated antigen 7 |
Gene namesi | Name:Spag7 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:107380, Spag7 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000072098 | 2 – 227 | Sperm-associated antigen 7Add BLAST | 226 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylalanineBy similarity | 1 | |
Modified residuei | 114 | PhosphoserineCombined sources | 1 | |
Modified residuei | 158 | PhosphoserineBy similarity | 1 | |
Modified residuei | 202 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | Q7TNE3 |
jPOSTi | Q7TNE3 |
MaxQBi | Q7TNE3 |
PaxDbi | Q7TNE3 |
PeptideAtlasi | Q7TNE3 |
PRIDEi | Q7TNE3 |
PTM databases
iPTMneti | Q7TNE3 |
PhosphoSitePlusi | Q7TNE3 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000018287, Expressed in adult mammalian kidney and 300 other tissues |
ExpressionAtlasi | Q7TNE3, baseline and differential |
Genevisiblei | Q7TNE3, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 229814, 1 interactor |
STRINGi | 10090.ENSMUSP00000018431 |
Miscellaneous databases
RNActi | Q7TNE3, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 46 – 109 | R3HPROSITE-ProRule annotationAdd BLAST | 64 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 35 – 51 | Nuclear localization signalSequence analysisAdd BLAST | 17 | |
Motifi | 122 – 139 | Nuclear localization signalSequence analysisAdd BLAST | 18 |
Phylogenomic databases
eggNOGi | ENOG502QW1E, Eukaryota |
GeneTreei | ENSGT00390000001520 |
HOGENOMi | CLU_091198_0_0_1 |
InParanoidi | Q7TNE3 |
OMAi | HRSVIHE |
OrthoDBi | 1416114at2759 |
PhylomeDBi | Q7TNE3 |
TreeFami | TF323631 |
Family and domain databases
CDDi | cd02636, R3H_sperm-antigen, 1 hit |
Gene3Di | 3.30.1370.50, 1 hit |
InterProi | View protein in InterPro IPR001374, R3H_dom IPR036867, R3H_dom_sf IPR034068, R3H_sperm-antigen IPR017330, SPAG7 |
PANTHERi | PTHR13498, PTHR13498, 1 hit |
Pfami | View protein in Pfam PF01424, R3H, 1 hit |
PIRSFi | PIRSF037943, Sperm-assoc_antigen_PAG7, 1 hit |
SMARTi | View protein in SMART SM00393, R3H, 1 hit |
SUPFAMi | SSF82708, SSF82708, 1 hit |
PROSITEi | View protein in PROSITE PS51061, R3H, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q7TNE3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADLLGSILS SMEKPPSLGD QESRRKAREQ AARLKKLQEQ DKQQKVEFRK
60 70 80 90 100
RMEKEVSDFI QDSGQVKKKF QPMNKIERSI LHDVVEVAGL TSFSFGEDDD
110 120 130 140 150
CRYVMIFKKE FAPSDEELDS YRHGEEWDPQ KAEEKRKLKE LAQKQEEEAA
160 170 180 190 200
QQGPAVVSPA SDYKDKYSHL IGKGAAKDAA HMLQANKTYG CVPVANKRDT
210 220
RSIEEAMNEI RAKKRLRQSG EELPTTS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ5SX56 | Q5SX56_MOUSE | Sperm-associated antigen 7 | Spag7 | 155 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 163 | Y → N in BAC36855 (PubMed:16141072).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK042294 mRNA Translation: BAE20629.1 AK077543 mRNA Translation: BAC36855.1 AK166184 mRNA Translation: BAE38615.1 AL596117 Genomic DNA No translation available. BC046751 mRNA Translation: AAH46751.1 BC055821 mRNA Translation: AAH55821.1 |
CCDSi | CCDS24962.1 |
RefSeqi | NP_001161141.1, NM_001167669.1 NP_766149.2, NM_172561.3 |
Genome annotation databases
Ensembli | ENSMUST00000018431; ENSMUSP00000018431; ENSMUSG00000018287 |
GeneIDi | 216873 |
KEGGi | mmu:216873 |
UCSCi | uc007jvz.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK042294 mRNA Translation: BAE20629.1 AK077543 mRNA Translation: BAC36855.1 AK166184 mRNA Translation: BAE38615.1 AL596117 Genomic DNA No translation available. BC046751 mRNA Translation: AAH46751.1 BC055821 mRNA Translation: AAH55821.1 |
CCDSi | CCDS24962.1 |
RefSeqi | NP_001161141.1, NM_001167669.1 NP_766149.2, NM_172561.3 |
3D structure databases
SMRi | Q7TNE3 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 229814, 1 interactor |
STRINGi | 10090.ENSMUSP00000018431 |
PTM databases
iPTMneti | Q7TNE3 |
PhosphoSitePlusi | Q7TNE3 |
Proteomic databases
EPDi | Q7TNE3 |
jPOSTi | Q7TNE3 |
MaxQBi | Q7TNE3 |
PaxDbi | Q7TNE3 |
PeptideAtlasi | Q7TNE3 |
PRIDEi | Q7TNE3 |
Protocols and materials databases
Antibodypediai | 5775, 76 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000018431; ENSMUSP00000018431; ENSMUSG00000018287 |
GeneIDi | 216873 |
KEGGi | mmu:216873 |
UCSCi | uc007jvz.2, mouse |
Organism-specific databases
CTDi | 9552 |
MGIi | MGI:107380, Spag7 |
Phylogenomic databases
eggNOGi | ENOG502QW1E, Eukaryota |
GeneTreei | ENSGT00390000001520 |
HOGENOMi | CLU_091198_0_0_1 |
InParanoidi | Q7TNE3 |
OMAi | HRSVIHE |
OrthoDBi | 1416114at2759 |
PhylomeDBi | Q7TNE3 |
TreeFami | TF323631 |
Miscellaneous databases
BioGRID-ORCSi | 216873, 1 hit in 17 CRISPR screens |
ChiTaRSi | Spag7, mouse |
PROi | PR:Q7TNE3 |
RNActi | Q7TNE3, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000018287, Expressed in adult mammalian kidney and 300 other tissues |
ExpressionAtlasi | Q7TNE3, baseline and differential |
Genevisiblei | Q7TNE3, MM |
Family and domain databases
CDDi | cd02636, R3H_sperm-antigen, 1 hit |
Gene3Di | 3.30.1370.50, 1 hit |
InterProi | View protein in InterPro IPR001374, R3H_dom IPR036867, R3H_dom_sf IPR034068, R3H_sperm-antigen IPR017330, SPAG7 |
PANTHERi | PTHR13498, PTHR13498, 1 hit |
Pfami | View protein in Pfam PF01424, R3H, 1 hit |
PIRSFi | PIRSF037943, Sperm-assoc_antigen_PAG7, 1 hit |
SMARTi | View protein in SMART SM00393, R3H, 1 hit |
SUPFAMi | SSF82708, SSF82708, 1 hit |
PROSITEi | View protein in PROSITE PS51061, R3H, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SPAG7_MOUSE | |
Accessioni | Q7TNE3Primary (citable) accession number: Q7TNE3 Secondary accession number(s): Q3TM27, Q80XJ8, Q8BK16 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 12, 2005 |
Last sequence update: | October 1, 2003 | |
Last modified: | February 10, 2021 | |
This is version 124 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot