UniProtKB - Q7TMI6 (Q7TMI6_MOUSE)
Protein
Submitted name:
Zinc finger protein 263
Gene
Zfp263
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: MGI
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: MGI
- sequence-specific double-stranded DNA binding Source: MGI
GO - Biological processi
- negative regulation of transcription by RNA polymerase II Source: MGI
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein 263Imported |
Gene namesi | Name:Zfp263Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1921370, Zfp263 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationPTM / Processingi
Proteomic databases
PRIDEi | Q7TMI6 |
PTM databases
iPTMneti | Q7TMI6 |
PhosphoSitePlusi | Q7TMI6 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 125 | SCAN boxInterPro annotationAdd BLAST | 83 | |
Domaini | 378 – 405 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 434 – 461 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 462 – 489 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 490 – 517 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 518 – 545 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 572 – 599 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 600 – 627 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 628 – 655 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 656 – 680 | C2H2-typeInterPro annotationAdd BLAST | 25 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 147 – 191 | DisorderedSequence analysisAdd BLAST | 45 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.ARBA annotation
Keywords - Domaini
RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationFamily and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit cd07936, SCAN, 1 hit |
Gene3Di | 1.10.4020.10, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR003309, SCAN_dom IPR038269, SCAN_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF02023, SCAN, 1 hit PF00096, zf-C2H2, 9 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00431, SCAN, 1 hit SM00355, ZnF_C2H2, 9 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 6 hits |
PROSITEi | View protein in PROSITE PS50804, SCAN_BOX, 1 hit PS00028, ZINC_FINGER_C2H2_1, 9 hits PS50157, ZINC_FINGER_C2H2_2, 9 hits |
i Sequence
Sequence statusi: Complete.
Q7TMI6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTMAAGPSSQ EPEGLLIVKL EEDCAWSHEV PPPEPEPSPE ASHLRFRRFR
60 70 80 90 100
FQDAPGPREA LSRLQELCRG WLRPEMRTKE QILELLVLEQ FLTILPQEIQ
110 120 130 140 150
SRVQELRPES GEEAVTLVER MQKELGKLRQ QVTNQGRGAE VLLEEPLPLE
160 170 180 190 200
TAGESPSFKL EPMETERSPG PRLQELLDPS PQRDSQAVKE RALSAPWLSL
210 220 230 240 250
FPPEGNVEDK DMTGTQLPES LEDMAMYISQ EWDHQDPSKR ALSRYMVQDS
260 270 280 290 300
YENSGTLESS IPSQEVSSTH VEQGEKLWDS SVQTCKEGMN PRNPVPGVEK
310 320 330 340 350
FENQERNVES VSPESTHPPV LLPGQARREV PWSPEQGRLD DREGHWECPP
360 370 380 390 400
EDKIEESLVG TPSCKGLVQA KEQPKKLHLC ALCGKNFSNN SNLIRHQRIH
410 420 430 440 450
AAEKLCMDVE CGEVFGGHPH FLSLHRTHIG EEAHKCLECG KCFSQNTHLT
460 470 480 490 500
RHQRTHTGEK PSQCNACGKS FSCNSNLNRH QRTHTGEKPY KCPECGEIFA
510 520 530 540 550
HSSNLLRHQR IHTGERPYRC SECGKSFSRS SHLVIHERTH EKERLDPFPE
560 570 580 590 600
CGQGMNDSAP FLTNHRVEKK LFECSTCGKS FRQGMHLTRH QRTHTGEKPY
610 620 630 640 650
KCILCGENFS HRSNLIRHQR IHTGEKPYTC HECGDSFSHS SNRIRHLRTH
660 670 680
TGERPYKCSE CGESFSRSSR LTSHQRTHTG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC056222 mRNA Translation: AAH56222.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC056222 mRNA Translation: AAH56222.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
PTM databases
iPTMneti | Q7TMI6 |
PhosphoSitePlusi | Q7TMI6 |
Proteomic databases
PRIDEi | Q7TMI6 |
Organism-specific databases
MGIi | MGI:1921370, Zfp263 |
Miscellaneous databases
ChiTaRSi | Zfp263, mouse |
SOURCEi | Search... |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit cd07936, SCAN, 1 hit |
Gene3Di | 1.10.4020.10, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR003309, SCAN_dom IPR038269, SCAN_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF02023, SCAN, 1 hit PF00096, zf-C2H2, 9 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00431, SCAN, 1 hit SM00355, ZnF_C2H2, 9 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 6 hits |
PROSITEi | View protein in PROSITE PS50804, SCAN_BOX, 1 hit PS00028, ZINC_FINGER_C2H2_1, 9 hits PS50157, ZINC_FINGER_C2H2_2, 9 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q7TMI6_MOUSE | |
Accessioni | Q7TMI6Primary (citable) accession number: Q7TMI6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2003 |
Last sequence update: | October 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 120 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |