UniProtKB - Q7T918 (Q7T918_9FLAV)
Protein
Core protein
Gene
N/A
Organism
Yokose virus
Status
Functioni
Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.ARBA annotation
Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.PROSITE-ProRule annotation
Catalytic activityi
- EC:3.6.4.13ARBA annotation
- a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + H+ + phosphateARBA annotationEC:3.6.1.15ARBA annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 1550 | Charge relay system; for serine protease NS3 activityUniRule annotation | 1 | |
Active sitei | 1574 | Charge relay system; for serine protease NS3 activityUniRule annotation | 1 | |
Active sitei | 1635 | Charge relay system; for serine protease NS3 activityUniRule annotation | 1 | |
Binding sitei | 2575 | S-adenosyl-L-methionineCombined sources | 1 | |
Binding sitei | 2629 | S-adenosyl-L-methionineCombined sources | 1 | |
Binding sitei | 2665 | S-adenosyl-L-methionineCombined sources | 1 | |
Metal bindingi | 2959 | Zinc 1UniRule annotation | 1 | |
Metal bindingi | 2963 | Zinc 1; via tele nitrogenUniRule annotation | 1 | |
Metal bindingi | 2968 | Zinc 1UniRule annotation | 1 | |
Metal bindingi | 2971 | Zinc 1UniRule annotation | 1 | |
Metal bindingi | 3235 | Zinc 2; via tele nitrogenUniRule annotation | 1 | |
Metal bindingi | 3251 | Zinc 2UniRule annotation | 1 | |
Metal bindingi | 3370 | Zinc 2UniRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- double-stranded RNA binding Source: InterPro
- metal ion binding Source: UniProtKB-KW
- mRNA (guanine-N7-)-methyltransferase activity Source: InterPro
- mRNA (nucleoside-2'-O-)-methyltransferase activity Source: InterPro
- protein dimerization activity Source: InterPro
- RNA-directed 5'-3' RNA polymerase activity Source: UniProtKB-KW
- RNA helicase activity Source: UniProtKB-EC
- serine-type endopeptidase activity Source: InterPro
- structural molecule activity Source: InterPro
GO - Biological processi
- fusion of virus membrane with host endosome membrane Source: UniProtKB-KW
- induction by virus of host autophagy Source: UniProtKB-KW
- suppression by virus of host STAT2 activity Source: UniProtKB-KW
- suppression by virus of host type I interferon-mediated signaling pathway Source: UniProtKB-KW
- viral RNA genome replication Source: InterPro
- virion attachment to host cell Source: UniProtKB-KW
Keywordsi
Molecular function | HelicaseARBA annotation, Hydrolase, MethyltransferaseARBA annotation, Nucleotidyltransferase, Protease, RNA-bindingARBA annotation, RNA-directed RNA polymeraseARBA annotation, Serine proteaseARBA annotation, Transferase |
Biological process | Activation of host autophagy by virusARBA annotation, Fusion of virus membrane with host endosomal membraneARBA annotation, Fusion of virus membrane with host membrane, Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host interferon signaling pathway by virus, Inhibition of host STAT2 by virusARBA annotation, mRNA cappingARBA annotation, mRNA processing, Viral attachment to host cellARBA annotation, Viral immunoevasion, Viral penetration into host cytoplasm, Viral RNA replicationARBA annotation, Virus entry into host cell |
Ligand | ATP-binding, Metal-bindingUniRule annotationARBA annotation, Nucleotide-binding, S-adenosyl-L-methionineCombined sourcesARBA annotation, ZincUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Core proteinARBA annotation (EC:3.4.21.91ARBA annotation, EC:3.6.1.15ARBA annotation, EC:3.6.4.13ARBA annotation)Alternative name(s): Envelope protein EARBA annotation Flavivirin protease NS2B regulatory subunitARBA annotation Flavivirin protease NS3 catalytic subunitARBA annotation Genome polyproteinARBA annotation Matrix proteinARBA annotation Non-structural protein 1ARBA annotation Non-structural protein 2AARBA annotation Non-structural protein 2BARBA annotation Non-structural protein 3ARBA annotation Non-structural protein 4AARBA annotation Non-structural protein 4BARBA annotation Peptide 2kARBA annotation Peptide prARBA annotation Protein prMARBA annotation RNA-directed RNA polymerase NS5ARBA annotation Serine protease NS3ARBA annotation Serine protease subunit NS2BARBA annotation Small envelope protein MARBA annotation |
Organismi | Yokose virusImported |
Taxonomic identifieri | 64294 [NCBI] |
Taxonomic lineagei | Viruses › Riboviria › Orthornavirae › Kitrinoviricota › Flasuviricetes › Amarillovirales › Flaviviridae › Flavivirus |
Proteomesi |
|
Subcellular locationi
- Endoplasmic reticulum membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
- Endoplasmic reticulum membrane ARBA annotation; Peripheral membrane protein ARBA annotation; Cytoplasmic side ARBA annotation
- Endoplasmic reticulum membrane ARBA annotation; Peripheral membrane protein ARBA annotation; Lumenal side ARBA annotation
- Host endoplasmic reticulum membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
- Host endoplasmic reticulum membrane ARBA annotation; Peripheral membrane protein ARBA annotation; Cytoplasmic side ARBA annotation
- Host endoplasmic reticulum membrane ARBA annotation; Peripheral membrane protein ARBA annotation; Lumenal side ARBA annotation
- Host nucleus ARBA annotation
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
- Membrane ARBA annotation; Peripheral membrane protein ARBA annotation; Cytoplasmic side ARBA annotation
- Nucleus ARBA annotation
- Secreted ARBA annotation
- Virion membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 110 – 129 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 730 – 759 | HelicalSequence analysisAdd BLAST | 30 | |
Transmembranei | 766 – 786 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1147 – 1163 | HelicalSequence analysisAdd BLAST | 17 | |
Transmembranei | 1175 – 1194 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 1214 – 1235 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 1244 – 1261 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 1303 – 1323 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1335 – 1357 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 1394 – 1411 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 1463 – 1490 | HelicalSequence analysisAdd BLAST | 28 | |
Transmembranei | 2166 – 2189 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 2196 – 2214 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 2220 – 2236 | HelicalSequence analysisAdd BLAST | 17 | |
Transmembranei | 2248 – 2265 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 2369 – 2393 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 2440 – 2459 | HelicalSequence analysisAdd BLAST | 20 |
GO - Cellular componenti
- extracellular region Source: UniProtKB-SubCell
- host cell endoplasmic reticulum membrane Source: UniProtKB-SubCell
- host cell nucleus Source: UniProtKB-SubCell
- integral component of membrane Source: UniProtKB-UniRule
- viral capsid Source: UniProtKB-KW
- virion membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Capsid proteinARBA annotation, Host endoplasmic reticulumPROSITE-ProRule annotationARBA annotation, Host membranePROSITE-ProRule annotationARBA annotation, Host nucleusARBA annotation, Membrane, SecretedARBA annotation, VirionPTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 299 ↔ 326 | UniRule annotation | ||
Disulfide bondi | 356 ↔ 412 | UniRule annotation | ||
Disulfide bondi | 370 ↔ 401 | UniRule annotation | ||
Disulfide bondi | 388 ↔ 417 | UniRule annotation | ||
Disulfide bondi | 478 ↔ 576 | UniRule annotation | ||
Disulfide bondi | 593 ↔ 623 | UniRule annotation |
Keywords - PTMi
Disulfide bondUniRule annotationARBA annotation, GlycoproteinARBA annotation, PhosphoproteinARBA annotationStructurei
3D structure databases
SMRi | Q7T918 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q7T918 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1367 – 1496 | FLAVIVIRUS_NS2BInterPro annotationAdd BLAST | 130 | |
Domaini | 1497 – 1678 | Peptidase S7InterPro annotationAdd BLAST | 182 | |
Domaini | 1679 – 1835 | Helicase ATP-bindingInterPro annotationAdd BLAST | 157 | |
Domaini | 1830 – 2010 | Helicase C-terminalInterPro annotationAdd BLAST | 181 | |
Domaini | 2521 – 2785 | MRNA cap 0-1 NS5-type MTInterPro annotationAdd BLAST | 265 | |
Domaini | 3049 – 3200 | RdRp catalyticInterPro annotationAdd BLAST | 152 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 33 | DisorderedSequence analysisAdd BLAST | 33 | |
Regioni | 1419 – 1458 | Interacts with and activates NS3 proteasePROSITE-ProRule annotationAdd BLAST | 40 | |
Regioni | 1952 – 1975 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 2605 – 2606 | S-adenosyl-L-methionine bindingCombined sources | 2 | |
Regioni | 2650 – 2651 | S-adenosyl-L-methionine bindingCombined sources | 2 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 19 | PolarSequence analysisAdd BLAST | 19 |
Keywords - Domaini
Transmembrane, Transmembrane helixPROSITE-ProRule annotationARBA annotationFamily and domain databases
CDDi | cd12149, Flavi_E_C, 1 hit |
Gene3Di | 1.10.8.970, 1 hit 1.20.1280.260, 1 hit 2.40.10.10, 1 hit 2.60.260.50, 1 hit 2.60.40.350, 1 hit 2.60.98.10, 1 hit 3.30.387.10, 1 hit 3.30.67.10, 1 hit |
InterProi | View protein in InterPro IPR011492, DEAD_Flavivir IPR043502, DNA/RNA_pol_sf IPR000069, Env_glycoprot_M_flavivir IPR038302, Env_glycoprot_M_sf_flavivir IPR013755, Flav_gly_cen_dom_subdom1 IPR001122, Flavi_capsidC IPR027287, Flavi_E_Ig-like IPR026470, Flavi_E_Stem/Anchor_dom IPR038345, Flavi_E_Stem/Anchor_dom_sf IPR001157, Flavi_NS1 IPR000752, Flavi_NS2A IPR000487, Flavi_NS2B IPR000404, Flavi_NS4A IPR001528, Flavi_NS4B IPR002535, Flavi_propep IPR038688, Flavi_propep_sf IPR000336, Flavivir/Alphavir_Ig-like_sf IPR001850, Flavivirus_NS3_S7 IPR014412, Gen_Poly_FLV IPR011998, Glycoprot_cen/dimer IPR036253, Glycoprot_cen/dimer_sf IPR038055, Glycoprot_E_dimer_dom IPR013756, GlyE_cen_dom_subdom2 IPR014001, Helicase_ATP-bd IPR001650, Helicase_C IPR014756, Ig_E-set IPR026490, mRNA_cap_0/1_MeTrfase IPR027417, P-loop_NTPase IPR009003, Peptidase_S1_PA IPR043504, Peptidase_S1_PA_chymotrypsin IPR000208, RNA-dir_pol_flavivirus IPR007094, RNA-dir_pol_PSvirus IPR002877, rRNA_MeTrfase_FtsJ_dom IPR029063, SAM-dependent_MTases |
Pfami | View protein in Pfam PF01003, Flavi_capsid, 1 hit PF07652, Flavi_DEAD, 1 hit PF02832, Flavi_glycop_C, 1 hit PF00869, Flavi_glycoprot, 1 hit PF01004, Flavi_M, 1 hit PF00948, Flavi_NS1, 1 hit PF01005, Flavi_NS2A, 1 hit PF01002, Flavi_NS2B, 1 hit PF01350, Flavi_NS4A, 1 hit PF01349, Flavi_NS4B, 1 hit PF00972, Flavi_NS5, 1 hit PF01570, Flavi_propep, 1 hit PF01728, FtsJ, 1 hit PF00949, Peptidase_S7, 1 hit |
PIRSFi | PIRSF003817, Gen_Poly_FLV, 1 hit |
SMARTi | View protein in SMART SM00487, DEXDc, 1 hit SM00490, HELICc, 1 hit |
SUPFAMi | SSF50494, SSF50494, 1 hit SSF52540, SSF52540, 2 hits SSF53335, SSF53335, 1 hit SSF56672, SSF56672, 1 hit SSF56983, SSF56983, 1 hit SSF81296, SSF81296, 1 hit |
TIGRFAMsi | TIGR04240, flavi_E_stem, 1 hit |
PROSITEi | View protein in PROSITE PS51527, FLAVIVIRUS_NS2B, 1 hit PS51528, FLAVIVIRUS_NS3PRO, 1 hit PS51192, HELICASE_ATP_BIND_1, 1 hit PS51194, HELICASE_CTER, 1 hit PS50507, RDRP_SSRNA_POS, 1 hit PS51591, RNA_CAP01_NS5_MT, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7T918-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKNRRQNTRI SGVNIKKQNP KNKKQTKIKT SVVKRGKRSV QPFGFLNPIM
60 70 80 90 100
RVRALIVYLI TMILTGRQWT KGMKLFWKRV NPQMAIATLK RVRNITTNLL
110 120 130 140 150
TGLMKRKRRS SVSCELLLTL LLMVTVGALQ IGRMRFAGKI VLSINATKYD
160 170 180 190 200
IGKTFDIMNG TCTVMAVDVG NWCDDYVIYQ CPTLTENENP EDIDCWCYGV
210 220 230 240 250
PNVYVTYGRC KHDGQPRRNR RSVALTNHVE ETLNTRGERW AVDKIGKQQF
260 270 280 290 300
EKIERWIIRN PLYALAVVGI SYMLGSNVGQ RIIICILLLL VAPAYSTHCT
310 320 330 340 350
NVEKRDFLQS TSGSSWTTVV LEHGGCVTLS AKDKPSVDVW LSSVTINNPP
360 370 380 390 400
LTRKVCYKAT LSEHKTANHC PTAGEAFLDE ESDDQHICKR GFSDRGWGNG
410 420 430 440 450
CGLFGKGSIV ACSKFTCNHD MHLMEIDQNK IHFKVTAQVH TSERDATSKE
460 470 480 490 500
WKRETEFTMA SGPQVIGFAG YGTATVSCNL KTSMDLNNYY VSKMADEYFL
510 520 530 540 550
LNKQWVMDLP LPWTPATATS WREKHYLTHF DEPHATTVTV TSMGNQEGSL
560 570 580 590 600
KASMVGATKI SYSENKYHIK GGHAVCQIQL QGLTMKGSTY TMCKGGYSFS
610 620 630 640 650
KTPVDSGHQT VIMKVKVSKA TPCRIPVAVI DSMQSNINRG VVVTTNPVAF
660 670 680 690 700
EAATEVMIEV VPPFGESVIT IGNGEDRLTY QWHQEGSTIG KAFSETLKGL
710 720 730 740 750
ERLTIIGDDA WDFGSTGGIF NTIGKAIHTV FGGAFSAVFG GVSWIVKLLL
760 770 780 790 800
GVAFLWLGVN ARNGTLTLIL MTLGGILIFL GTGVGAEQAC AVSWERREFK
810 820 830 840 850
CGDGMFIFRD TNDFLGKYKM YPTSPREIAA VIAQTFSNGA CGLNSVDELE
860 870 880 890 900
HQMWKGIEDE INHVLSENGL DLSVVVQDPH NIYRRGGKSF SPAQRTLEYG
910 920 930 940 950
WKTWGKSFYS AVERKNNSFI IDALDQNECK NAERVWNSLE LEEFGFGVFK
960 970 980 990 1000
TKLFLKPRFD YSKKCPTYLL GTAVKHARAV HGDQNMWMES EHVNGTWQIT
1010 1020 1030 1040 1050
RLELQSYREC LWPPMHTAGI TSVMESDLFM PRELGGPVTL HNHIPGYATQ
1060 1070 1080 1090 1100
VYGAWHLPNM ELKREECPGT TVQVKDNCGK RGPSVRSTTA SNKVIPHWCC
1110 1120 1130 1140 1150
RSCTMPPVTY RTANECWYAM EIRPENMQEE HLVKSWVSAG EGRMCDHFSG
1160 1170 1180 1190 1200
GLFALIILMD LIIHHRLSPR KHLLLILLLA LLTVFGGVSM RDLARCLLLL
1210 1220 1230 1240 1250
GHTFNTMNSG TEVAHLAMVA LTKLRAGFIT GYFLARPLGP RGKFLLVVAL
1260 1270 1280 1290 1300
SLLQTTLPMN MEFMEWADSL GLVLALADAL YTMHADSWTM LGLIALNPLG
1310 1320 1330 1340 1350
NHMLVKTVTT ILFSVCAFVL VTRKSTSIRK TYPQLITAGL VELGMLRGWI
1360 1370 1380 1390 1400
LGLLVGLHRK NNGKVRSIDW TDGVTVLGVV AGLLGMLCGE REELLAPFVI
1410 1420 1430 1440 1450
GSILLLCYVF SMKSDGLELE RVADVTWDEE AEYSGEAERF DVTVNHNGEF
1460 1470 1480 1490 1500
NLIDQKPVPW SHVLMGTGLL IVSTVHPAGL VLAAFAFWYY QYTKQRSNIL
1510 1520 1530 1540 1550
WELPEVAERT PMLTEGVPDG VYRIMQKGVF GPQQKGVGVG KSGTFHTMWH
1560 1570 1580 1590 1600
VTHGSLLRLN GKLVTPSWAN VKKDLIAYGG PWRLTDQWVE NEDVQVIVCS
1610 1620 1630 1640 1650
PRAVIRNVQT TPGMFTTIEG KKIGAVSLDY PPGTSGSPII NKRGEVIGLY
1660 1670 1680 1690 1700
GNGILTEEKR FVSSIAQASV EETASPTPDI SLSKGNLHVL DLHPGSGKTR
1710 1720 1730 1740 1750
QVLPALLRKC VEKRLRTLVL APTKVVLSEM HEAVKDLPVR FHTSAALETK
1760 1770 1780 1790 1800
KTGALIDLMC HATLANRLLE PTRYVNWEVV VMDEAHFLDP HSIAVRGWMQ
1810 1820 1830 1840 1850
QLVTLKLAAV VLMTATPPGT SDPFPESNGT IEDTQVTIPD EPWKRGNEWI
1860 1870 1880 1890 1900
LDDPRPTAWF LPSIKASNIM AAFLKKNGKK VVVLNRKTFD KEYGTLKAEK
1910 1920 1930 1940 1950
PDFILTTDIA EMGANLPVER VIDPRTCMRP VLVDEKNRVE LQGPLPITAS
1960 1970 1980 1990 2000
SAAQRRGRIG RNPDRNTDSY MYEGETSEEN GDLVCWKEAL MILDNMEIPG
2010 2020 2030 2040 2050
GFTMSLFGSE ARKVEHVPGE YRLKPEARKR FRQLMRKYEF TPWLAWKVAK
2060 2070 2080 2090 2100
NTKEMEMSWI VQGPKENRVL NEFGENLTFK SRYGSIEKIQ PIWSDARMFA
2110 2120 2130 2140 2150
DGQTQKAFIE YATTTRSITA VIEKVAMVPE ALKDKVQDAF DTYYTLYKAE
2160 2170 2180 2190 2200
EKSRSYQIAL EQIPDALITT LCLGALAAAT GGILLYLLLP KGMSRMTLAF
2210 2220 2230 2240 2250
FTMLVTGAGL WMGGLSTVKV ASAMLVFFIL CVVLIPDTGM QRSIQDNYLA
2260 2270 2280 2290 2300
YFIISLISCV ALIVANENGY LEKTKEDLFG RRALNSSNVY ANLPVEKWLS
2310 2320 2330 2340 2350
LDLQPATSWT LYAVIVGVLS PLYHHIEHVN YGAISLQGIS QGAAALFQMD
2360 2370 2380 2390 2400
KGYPFMRLRI PLVLLLAGAI NNLTAITAGL GFLCAMIHWA LVLPGLKAKL
2410 2420 2430 2440 2450
AKQALRRTYH GVTKNAVVDG MCTNDLDAGD DMPEKFEKQL GTFVLITLVF
2460 2470 2480 2490 2500
LNVILNHNVK AFLEGMVLVS ASLQPLLTGV PNPYWNQQIA VGVAGLMRGN
2510 2520 2530 2540 2550
YMAAVGMAHA LWNAQANRRG GTGSGMTPGE AWKKQLNKLG KTQFEQYKRS
2560 2570 2580 2590 2600
CILEVDRTHA RDSLKNGIQN GIAVSRGSAK LRWMEERGYV KPTGIVVDLG
2610 2620 2630 2640 2650
CGRGGWSYYA ASLKNVKKVM AFTLGVQGHE KPIMRTTLGW NLIRFKDKTD
2660 2670 2680 2690 2700
VFNMEVIPGD TLLCDIGESS PSIAVEEQRT LKVLNCAKQW LQEGNYTEFC
2710 2720 2730 2740 2750
IKVLCPYTPL IMEELSRLQL KHGGGLVRVP LSRNSTHEMY WVSGTRTDVV
2760 2770 2780 2790 2800
GTVSNVSRLL TRRMLNKPQP PTLEDDVILD MGTRSMECDT GPIDEDKIRR
2810 2820 2830 2840 2850
RVDLLREEYK KTWFHDLNHP YRTWHYIGSY LTRGGGTAAS MTNGIVKLMS
2860 2870 2880 2890 2900
QPWDAVAGVA CMAMTDTTPF GQQRVFKEKV DTKPPEPNKT VRHVMAMTNS
2910 2920 2930 2940 2950
WIMKYLARNK QPRLCTKEEF IAKVRSHAAL GAFVPELEGW SSAHEAVHDQ
2960 2970 2980 2990 3000
RFWKLVDEER ELHKKGECRT CVYNMMGKRE KKPSEFGKAK GSRAIWYMWL
3010 3020 3030 3040 3050
GARFLEFEAL GFLNEDHWVS RKNSLSGVEG VGLQYLGHVL KTLERKSGTS
3060 3070 3080 3090 3100
YYADDTAGWD TRITIADLED EQDILTYMRL EHRILAEAVM NLAYKHKVVR
3110 3120 3130 3140 3150
VERPIQGGKT AMDIIYRQEH RGSGQVVTYA FNTITNMKVQ LIRMAESEEV
3160 3170 3180 3190 3200
LPDPSQEWTP EHGNTLWQWL NENGEDRLGR MAVSGDDCVV KPIDDRFATS
3210 3220 3230 3240 3250
LTYLNHMAKI RKDISEWKPS KPFMDIEEVP FCSHHFHKLI LRDGREIMAP
3260 3270 3280 3290 3300
CREQDELIGR ARISPGNGWL VRETAPLSKA YANMWKLFYF HRRDLRLMAN
3310 3320 3330 3340 3350
AINSAVPIDW VPTGRTTWSV HGKGEWMTSE DMLDVWNRVW ITDNPFMNRK
3360 3370 3380 3390 3400
TLIGKWQDIP YISKSQDVRC GSMIGTSKRS SWAEALPHTV QKVRGIVGTQ
3410 3420
ERYRDYLETQ NRFRTIVQHL VGDIL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB114858 Genomic RNA Translation: BAC79364.1 |
RefSeqi | NP_872627.1, NC_005039.1 |
Genome annotation databases
GeneIDi | 1727359 |
KEGGi | vg:1727359 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB114858 Genomic RNA Translation: BAC79364.1 |
RefSeqi | NP_872627.1, NC_005039.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3GCZ | X-ray | 1.70 | A | 2520-2784 | [»] | |
SMRi | Q7T918 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Genome annotation databases
GeneIDi | 1727359 |
KEGGi | vg:1727359 |
Miscellaneous databases
EvolutionaryTracei | Q7T918 |
Family and domain databases
CDDi | cd12149, Flavi_E_C, 1 hit |
Gene3Di | 1.10.8.970, 1 hit 1.20.1280.260, 1 hit 2.40.10.10, 1 hit 2.60.260.50, 1 hit 2.60.40.350, 1 hit 2.60.98.10, 1 hit 3.30.387.10, 1 hit 3.30.67.10, 1 hit |
InterProi | View protein in InterPro IPR011492, DEAD_Flavivir IPR043502, DNA/RNA_pol_sf IPR000069, Env_glycoprot_M_flavivir IPR038302, Env_glycoprot_M_sf_flavivir IPR013755, Flav_gly_cen_dom_subdom1 IPR001122, Flavi_capsidC IPR027287, Flavi_E_Ig-like IPR026470, Flavi_E_Stem/Anchor_dom IPR038345, Flavi_E_Stem/Anchor_dom_sf IPR001157, Flavi_NS1 IPR000752, Flavi_NS2A IPR000487, Flavi_NS2B IPR000404, Flavi_NS4A IPR001528, Flavi_NS4B IPR002535, Flavi_propep IPR038688, Flavi_propep_sf IPR000336, Flavivir/Alphavir_Ig-like_sf IPR001850, Flavivirus_NS3_S7 IPR014412, Gen_Poly_FLV IPR011998, Glycoprot_cen/dimer IPR036253, Glycoprot_cen/dimer_sf IPR038055, Glycoprot_E_dimer_dom IPR013756, GlyE_cen_dom_subdom2 IPR014001, Helicase_ATP-bd IPR001650, Helicase_C IPR014756, Ig_E-set IPR026490, mRNA_cap_0/1_MeTrfase IPR027417, P-loop_NTPase IPR009003, Peptidase_S1_PA IPR043504, Peptidase_S1_PA_chymotrypsin IPR000208, RNA-dir_pol_flavivirus IPR007094, RNA-dir_pol_PSvirus IPR002877, rRNA_MeTrfase_FtsJ_dom IPR029063, SAM-dependent_MTases |
Pfami | View protein in Pfam PF01003, Flavi_capsid, 1 hit PF07652, Flavi_DEAD, 1 hit PF02832, Flavi_glycop_C, 1 hit PF00869, Flavi_glycoprot, 1 hit PF01004, Flavi_M, 1 hit PF00948, Flavi_NS1, 1 hit PF01005, Flavi_NS2A, 1 hit PF01002, Flavi_NS2B, 1 hit PF01350, Flavi_NS4A, 1 hit PF01349, Flavi_NS4B, 1 hit PF00972, Flavi_NS5, 1 hit PF01570, Flavi_propep, 1 hit PF01728, FtsJ, 1 hit PF00949, Peptidase_S7, 1 hit |
PIRSFi | PIRSF003817, Gen_Poly_FLV, 1 hit |
SMARTi | View protein in SMART SM00487, DEXDc, 1 hit SM00490, HELICc, 1 hit |
SUPFAMi | SSF50494, SSF50494, 1 hit SSF52540, SSF52540, 2 hits SSF53335, SSF53335, 1 hit SSF56672, SSF56672, 1 hit SSF56983, SSF56983, 1 hit SSF81296, SSF81296, 1 hit |
TIGRFAMsi | TIGR04240, flavi_E_stem, 1 hit |
PROSITEi | View protein in PROSITE PS51527, FLAVIVIRUS_NS2B, 1 hit PS51528, FLAVIVIRUS_NS3PRO, 1 hit PS51192, HELICASE_ATP_BIND_1, 1 hit PS51194, HELICASE_CTER, 1 hit PS50507, RDRP_SSRNA_POS, 1 hit PS51591, RNA_CAP01_NS5_MT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q7T918_9FLAV | |
Accessioni | Q7T918Primary (citable) accession number: Q7T918 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2003 |
Last sequence update: | October 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 152 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |