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Entry version 105 (29 Sep 2021)
Sequence version 1 (01 Oct 2003)
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Protein
Submitted name:

Nil per os

Gene

rbm19

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • RNA binding Source: ZFIN

GO - Biological processi

  • digestive tract morphogenesis Source: ZFIN
  • mRNA splicing, via spliceosome Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nil per osImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rbm19Imported
Synonyms:npoImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-031125-3, rbm19

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2 – 79RRMInterPro annotationAdd BLAST78
Domaini289 – 364RRMInterPro annotationAdd BLAST76
Domaini398 – 476RRMInterPro annotationAdd BLAST79
Domaini584 – 656RRMInterPro annotationAdd BLAST73
Domaini701 – 782RRMInterPro annotationAdd BLAST82
Domaini804 – 883RRMInterPro annotationAdd BLAST80

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni83 – 119DisorderedSequence analysisAdd BLAST37
Regioni160 – 288DisorderedSequence analysisAdd BLAST129
Regioni476 – 507DisorderedSequence analysisAdd BLAST32
Regioni663 – 698DisorderedSequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi85 – 119Basic and acidic residuesSequence analysisAdd BLAST35
Compositional biasi160 – 179Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi180 – 203Acidic residuesSequence analysisAdd BLAST24
Compositional biasi204 – 238Basic and acidic residuesSequence analysisAdd BLAST35
Compositional biasi239 – 258Acidic residuesSequence analysisAdd BLAST20
Compositional biasi263 – 285Polar residuesSequence analysisAdd BLAST23
Compositional biasi683 – 697Acidic residuesSequence analysisAdd BLAST15

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
TALIEYC

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12564, RRM1_RBM19, 1 hit
cd12502, RRM2_RMB19, 1 hit
cd12567, RRM3_RBM19, 1 hit
cd12569, RRM4_RBM19, 1 hit
cd12318, RRM5_RBM19_like, 1 hit
cd12571, RRM6_RBM19, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR034419, RBM19_RRM3
IPR034420, RBM19_RRM4
IPR034423, RBM19_RRM5
IPR034421, RBM19_RRM6
IPR034418, RMB19_RRM1
IPR034417, RMB19_RRM2
IPR000504, RRM_dom
IPR003954, RRM_dom_euk

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076, RRM_1, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360, RRM, 6 hits
SM00361, RRM_1, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928, SSF54928, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102, RRM, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7T1C5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRLIVKNLP NGMKEERFRK MFADFGTLTD CALKFTKDGK FRKFGFVGFK
60 70 80 90 100
TEEDAQKALK HFNKSFVDTS RVTVELCTDF GDPNKARPWS KHTRQPSQKD
110 120 130 140 150
TEEKKTHEQG EKEKKKPKKI LNVLGDLEKD ESFQEFLAVH QKRGQVPTWA
160 170 180 190 200
NDTVEATAVR PEMEKKKEKK QKAAVEDDYL NFDSDESEES SDDGEDAADE
210 220 230 240 250
EDKQDNEKEA LKTGLSDMDY LRSKMVEKSD MLDEKDDESS ASAADENEED
260 270 280 290 300
EGEEEEESTV QHTDSAYESG EKTSSQKSTR PAIEPTTEFT VKLRGAPFNV
310 320 330 340 350
KEQQVKEFMM PLKPVAIRFA KNSDGRNSGY VYVDLRSEAE VERALRLDKD
360 370 380 390 400
YMGGRYIEVF RANNFKNDRR SSKRSEMEKN FVRELKDDEE EEDVAESGRL
410 420 430 440 450
FIRNMPYTCT EEDLKEVFSK HGPLSEVLFP IDSLTKKPKG FAFVTYMIPE
460 470 480 490 500
NAVSALAQLD GQTFQGRVLH VMASRLKKEK ADQGPDAPGS SSYKRKKDAK
510 520 530 540 550
DKAASGSSHN WNTLFLGTSA VADAIAEKYN TTKSQVLDHE SDGSLAVRMA
560 570 580 590 600
LGETQIVQET RQFLLDNGVS LDSFSQASGE RSKCVILVKN LPSGVQVADL
610 620 630 640 650
EALFSPHGSL GRVLLPPSGL TAIVEFLEPT EAKRAFMKLA YTKFQHVPLY
660 670 680 690 700
LEWAPVAVFT TPSAPRPEPQ TKEKSAVKND SVQNEEEEEE EEEDDQILPG
710 720 730 740 750
STLFIKNLNF ITSEETLQKT FSKCGVVKSC TISKKRDKAG KLLSMGYGFV
760 770 780 790 800
QYKTPEAAQK AMRQLQHCTV DEHQLEVKIS EREVKLGVAQ AKRKKQTARK
810 820 830 840 850
QTTSKILVRN IPFQATVKEL RELFCTFGEL KTVRLPKKGI GGSHRGFGFI
860 870 880 890 900
DFLTKQDAKK AFSALCHSTH LYGRRLVLEW ADAEETVDDL RRKTAQHFHD
910 920
APKKKRKAEV LEGILEQMEV GDGDGE
Length:926
Mass (Da):104,559
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC30BAAF5FE4FB64D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY299514 mRNA Translation: AAP82506.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY299514 mRNA Translation: AAP82506.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Organism-specific databases

ZFINiZDB-GENE-031125-3, rbm19

Phylogenomic databases

OMAiTALIEYC

Family and domain databases

CDDicd12564, RRM1_RBM19, 1 hit
cd12502, RRM2_RMB19, 1 hit
cd12567, RRM3_RBM19, 1 hit
cd12569, RRM4_RBM19, 1 hit
cd12318, RRM5_RBM19_like, 1 hit
cd12571, RRM6_RBM19, 1 hit
Gene3Di3.30.70.330, 6 hits
InterProiView protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR034419, RBM19_RRM3
IPR034420, RBM19_RRM4
IPR034423, RBM19_RRM5
IPR034421, RBM19_RRM6
IPR034418, RMB19_RRM1
IPR034417, RMB19_RRM2
IPR000504, RRM_dom
IPR003954, RRM_dom_euk
PfamiView protein in Pfam
PF00076, RRM_1, 6 hits
SMARTiView protein in SMART
SM00360, RRM, 6 hits
SM00361, RRM_1, 2 hits
SUPFAMiSSF54928, SSF54928, 5 hits
PROSITEiView protein in PROSITE
PS50102, RRM, 6 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ7T1C5_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7T1C5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: September 29, 2021
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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