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UniProtKB - Q7SEW1 (Q7SEW1_NEUCR)

Entry version 78 (07 Oct 2020)
Sequence version 1 (15 Dec 2003)
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Protein
Submitted name:

Small oligopeptide transporter

Gene

NCU03171

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPeptide transportARBA annotation, Protein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Small oligopeptide transporterImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:NCU03171Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri367110 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Sordariomycetidae › Sordariales › Sordariaceae › Neurospora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001805 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1, Linkage Group I

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		FungiDB:NCU03171

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei104 – 124HelicalSequence analysisAdd BLAST21
Transmembranei131 – 152HelicalSequence analysisAdd BLAST22
Transmembranei178 – 200HelicalSequence analysisAdd BLAST23
Transmembranei212 – 230HelicalSequence analysisAdd BLAST19
Transmembranei327 – 344HelicalSequence analysisAdd BLAST18
Transmembranei351 – 374HelicalSequence analysisAdd BLAST24
Transmembranei428 – 448HelicalSequence analysisAdd BLAST21
Transmembranei481 – 501HelicalSequence analysisAdd BLAST21
Transmembranei507 – 533HelicalSequence analysisAdd BLAST27
Transmembranei594 – 613HelicalSequence analysisAdd BLAST20
Transmembranei633 – 651HelicalSequence analysisAdd BLAST19
Transmembranei663 – 679HelicalSequence analysisAdd BLAST17
Transmembranei686 – 702HelicalSequence analysisAdd BLAST17
Transmembranei708 – 724HelicalSequence analysisAdd BLAST17
Transmembranei736 – 758HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the oligopeptide OPT transporter family.ARBA annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004965_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q7SEW1

Identification of Orthologs from Complete Genome Data

More...OMAi		AMIWPAD

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004648, Oligpept_transpt
IPR004813, OPT

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03169, OPT, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00727, ISP4_OPT, 1 hit
TIGR00728, OPT_sfam, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7SEW1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRNFFRRRH GDEDVMPDMV DDGSLEGDST GIEALTALKR FEKMHRLDPN 
        60         70         80         90        100
LPLDELDEVE TALNSANIEK GTEIDQILAE DNSPYPEVRA SVRNYDVEMP 
       110        120        130        140        150
VNTIRAWTIG MLLCTIGSAV NMLLSLRNPS ISLSTLAIQL IAYPIGLGWD 
       160        170        180        190        200
LIFPDRVFTV FGIKFNLKPG PFNFKEHVII VVMSNAAYGG GALYATDVIL 
       210        220        230        240        250
AQEIWYKQSF GWAWQILFGI STLCTGYGLA GLARRFLVWP AAMIWPADLI 
       260        270        280        290        300
NCTLFYTLHD HSPSDPARTN GWSISRYRWF LIVMAGSFAW YWFPGYLFQG 
       310        320        330        340        350
LSWMCWITWI WPDNVIVNQL FGGQSGYGLF PITLDWSIIS GYLLSPLASP 
       360        370        380        390        400
FHAIANVVGG VTFFFVIVSL GIQYSNIWYS AYLPVQESHS YDNTGKRYVV 
       410        420        430        440        450
LRILNENLHF DEAKYHAYSP LYLPTQFALA YGLSFAAVAA VIVHVGLYHG 
       460        470        480        490        500
KDIWNQWKLA RHQEDDVHMR LMKKYRDAED WWYIILFAVM LGMSFAVVCA 
       510        520        530        540        550
WDTGFPWWAF IICILIPVVW TIPIGIIQAI TNIQLGLNVL TEYVIGYMLP 
       560        570        580        590        600
GRPLVMMMFK NYGYLVMSQA LYFIQDLKLG HYMKVPPRVM FWSQLIASVW 
       610        620        630        640        650
SAIVQIAVMN WALGAIPDIC TDGQANQFDC PSAKVFFTAS VIWGAIGPAR 
       660        670        680        690        700
MFSGKALYSS LQWFWLVGAV APVISWFFVR RYPRSLWRYV NFPLVFGGSG 
       710        720        730        740        750
WIPPATVYIY YCWGIVGTVF NFFIRRRKTG WWLQYNYLTS AALDVGLLLS 
       760        770        780        790        800
TLVIFFSLTL SHTKAPEWFG NTVAKSTMDT TATAVQKLVP PGEIFGPREW 

P
Length:801
Mass (Da):91,089
Last modified:December 15, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBB57F5FEE8B8FBF1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CM002236 Genomic DNA Translation: EAA35341.1

NCBI Reference Sequences

More...RefSeqi		XP_964577.1, XM_959484.3

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		EAA35341; EAA35341; NCU03171

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3880717

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ncr:NCU03171

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002236 Genomic DNA Translation: EAA35341.1
RefSeqiXP_964577.1, XM_959484.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblFungiiEAA35341; EAA35341; NCU03171
GeneIDi3880717
KEGGincr:NCU03171

Organism-specific databases

EuPathDBiFungiDB:NCU03171

Phylogenomic databases

HOGENOMiCLU_004965_1_1_1
InParanoidiQ7SEW1
OMAiAMIWPAD

Family and domain databases

InterProiView protein in InterPro
IPR004648, Oligpept_transpt
IPR004813, OPT
PfamiView protein in Pfam
PF03169, OPT, 1 hit
TIGRFAMsiTIGR00727, ISP4_OPT, 1 hit
TIGR00728, OPT_sfam, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ7SEW1_NEUCR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7SEW1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: October 7, 2020
This is version 78 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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