Helicase swr-1

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. the chemical reaction it catalyzes. This information usually correlates with the presence of an EC (Enzyme Commission) number in the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• ATP binding Source: UniProtKB-KW
• DNA binding Source: UniProtKB-KW
• helicase activity Source: UniProtKB-KW

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• chromatin organization Source: UniProtKB-KW
• regulation of transcription, DNA-templated Source: UniProtKB-KW
• transcription, DNA-templated Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Motif

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MTTMMTDSGT ASDSGAGLVD STRNDTTTTT TTTTTPGDND ADDDNTNGTT 
        60         70         80         90        100
TGHHDNNETD NNSKSYSSTH HVPAIDNTST TNANDNEDAA GFLDRDQSPL 
       110        120        130        140        150
SSISSPLSEP DNFEFDTEPI PSILSPKSTT SDNHARDGET PELDEDGQPP 
       160        170        180        190        200
AKRRRVRETT PHNHSRKPKP ESPPWKKFEA EGPTTIITED GRRKSGRVNP 
       210        220        230        240        250
VLLGMKPSDK KVTRKAIQTS PVSNKSSAST SRKPAPASSS NSKHAPAKMP 
       260        270        280        290        300
PPPPPPKAPA RKSATTHETR PSASRSRRRS PSPRRPATPP KPAAVGTRRS 
       310        320        330        340        350
TRQALAHSRA SYDDGQLSPG ASRATPRIKL KVRPPLTVIP LVHPNQANVR 
       360        370        380        390        400
PKLGPTFEEY FARAHEIPVE EGGQHIPDEE PKYTDEMALQ DAKVILRVEK 
       410        420        430        440        450
EVEPGGLLAP DRCSAFEPEA EEEPPRQWAH LDHLTKAMTN FRKLMYREQQ 
       460        470        480        490        500
LHMQAAKRIA IACEAEWRRR NPQPKTAEEI ELEEMEASKA KWRQVIRAFA 
       510        520        530        540        550
GTWENVRVEV NRRRLVEWEA EEQRRVKAAL NQAVNLSEQK LQQRQAQVDG 
       560        570        580        590        600
DEITDEDEDE DDEDLASGMP SVMGDEKESD EHSDQGSDEM SDENDEDEDE 
       610        620        630        640        650
DNMSSSEDDD KKSTASDEGL TQEELRAKYA NLPTLGTTDE TEETTKDVEM 
       660        670        680        690        700
ADAPAAMDGS VANDDDTSDE SVDMDDDLGS SEESDDDEEE EEDDEEEEES 
       710        720        730        740        750
DDEPAGLLGL FFGKSELKKL KEEAVTEEPS VEPAGDVEMT DASAALRPEL 
       760        770        780        790        800
QVNGHAHEAP ITNGTHTNEQ LASSQTEGAD DEVSLLVIPN DEIAAENTQT 
       810        820        830        840        850
AAEPGSGVVE KDFLTNDSSL KYPNEIVQSE NQTLPAKESV EAGGDLPMVD 
       860        870        880        890        900
APSTDDLQRE TAAAPSLEAP PNTRHDSQET VAATDMQSQS QTQSPKTTDT 
       910        920        930        940        950
KPTDVDTPHS ELAVSVQKPD SRQSSPQPTT PTVKTEIPFL LRGTLREYQH 
       960        970        980        990       1000
HGLDWLAGLY ANNTNGILAD EMGLGKTIQT IALLAHLACH HEVWGPHLVI 
      1010       1020       1030       1040       1050
VPTSVMLNWE MEFKKWCPGF KILTYYGNQE ERKRKRQGWN NDDVWNVCIT 
      1060       1070       1080       1090       1100
SYQMVLQDQQ VFRRRRWHYM ILDEAHNIKN FKSQRWQTLL GFNTQARLLL 
      1110       1120       1130       1140       1150
TGTPLQNNLT ELWSLLYFLA PPENGEGGFV DLTEFHNWFA RPESQILESG 
      1160       1170       1180       1190       1200
REQLDDEARA IIAKLHKVLR PYLLRRLKAD VEKQMPAKYE HVEFCRLSKR 
      1210       1220       1230       1240       1250
QRELYDGFLS RADTRETLQS GNYMSIINCL MQLRKVCNHP DLFVDRPIMT 
      1260       1270       1280       1290       1300
SFRMSRSVPA DYEWKEKFIR NRLLATKPMT TVNLSFLNMI PTEYEDLSKT 
      1310       1320       1330       1340       1350
HTDRIAQLSS HRILLDLREA QKVRANNAYT ALDPSSVKSN LVYLESAARW 
      1360       1370       1380       1390       1400
GRFEELQHCV YINALRRQQR PIYGKRLTEF LTLDTHLRPY KPRPRVPAKI 
      1410       1420       1430       1440       1450
MSWFEEDSFL LHNAIPTLQQ RAESMEMTIT KFACVTPAVV TGPEMNRFLL 
      1460       1470       1480       1490       1500
GERGIQLFED LDLKLSAPVK YAPYMPPQPP PDPWHEARMR LTIQFPDKRL 
      1510       1520       1530       1540       1550
LQYDCGKLQA LDKLLRKLQA GGHRALIFTQ MTKVLDILEQ FLNIHGHKYL 
      1560       1570       1580       1590       1600
RLDGATKVEQ RQILTDRFNH DPRILCFILS TRSGGLGINL TGADTVIFYD 
      1610       1620       1630       1640       1650
QDWNPAMDKQ CQDRCHRIGQ TRDVHIYRLV SEHTIEANIL RKASQKQMLD 
      1660       1670       1680       1690       1700
DVVIQEGEFT TDYFNRLSVR DVLGSNGEVI ASNEDDVAAN LAMDRVLGGP 
      1710       1720       1730       1740       1750
STTGAGGYDG TADGGGGASQ PPVRNVGRVL EMAEDREDVD AAKAAEKEIM 
      1760       1770       1780       1790       1800
QDEADFGEAG STRPGTPGDG LADLDGQLLG GEENKEVEDE VIEYNAWGER 
      1810       1820       1830       1840 
MHTIDEYMLG FMAKALEGTP LELPRDRKKG RDRNRNRKGK DSRKR      

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

Documents

1. SIMILARITY comments
   Index of protein domains and families