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Entry version 117 (13 Feb 2019)
Sequence version 2 (28 Nov 2006)
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Protein

Ovochymase-1

Gene

OVCH1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei87Charge relay systemBy similarity1
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi116CalciumBy similarity1
Active sitei139Charge relay systemBy similarity1
Active sitei237Charge relay systemBy similarity1
Active sitei615Charge relay systemBy similarity1
Active sitei664Charge relay systemBy similarity1
Active sitei763Charge relay systemBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Serine protease
LigandCalcium, Metal-binding

Protein family/group databases

MEROPS protease database

More...
MEROPSi
S01.322

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ovochymase-1 (EC:3.4.21.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OVCH1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000187950.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23080 OVCH1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7RTY7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134910581

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
OVCH1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
118573093

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_000026117923 – 46Activation peptideBy similarityAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000026118047 – 1134Ovochymase-1Add BLAST1088

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi52N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi72 ↔ 88By similarity
Glycosylationi99N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi173 ↔ 243By similarity
Disulfide bondi204 ↔ 222By similarity
Disulfide bondi233 ↔ 262By similarity
Glycosylationi324N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi341 ↔ 373By similarity
Disulfide bondi419 ↔ 446By similarity
Glycosylationi431N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi473 ↔ 494By similarity
Glycosylationi507N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi600 ↔ 616By similarity
Disulfide bondi698 ↔ 769By similarity
Disulfide bondi729 ↔ 747By similarity
Disulfide bondi759 ↔ 788By similarity
Disulfide bondi846 ↔ 873By similarity
Glycosylationi1106N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7RTY7

PeptideAtlas

More...
PeptideAtlasi
Q7RTY7

PRoteomics IDEntifications database

More...
PRIDEi
Q7RTY7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
68936

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7RTY7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7RTY7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000187950 Expressed in 77 organ(s), highest expression level in right lung

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7RTY7 baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA040253

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q7RTY7, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000326708

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q7RTY7

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7RTY7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini38 – 296Peptidase S1 1PROSITE-ProRule annotationAdd BLAST259
Domaini284 – 410CUB 1PROSITE-ProRule annotationAdd BLAST127
Domaini419 – 531CUB 2PROSITE-ProRule annotationAdd BLAST113
Domaini575 – 812Peptidase S1 2PROSITE-ProRule annotationAdd BLAST238
Domaini846 – 957CUB 3PROSITE-ProRule annotationAdd BLAST112

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase S1 family.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3627 Eukaryota
COG5640 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000172098

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7RTY7

Database of Orthologous Groups

More...
OrthoDBi
1314811at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7RTY7

TreeFam database of animal gene trees

More...
TreeFami
TF318987

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00041 CUB, 3 hits
cd00190 Tryp_SPc, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.290, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000859 CUB_dom
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR035914 Sperma_CUB_dom_sf
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00431 CUB, 2 hits
PF00089 Trypsin, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00722 CHYMOTRYPSIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00042 CUB, 2 hits
SM00020 Tryp_SPc, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49854 SSF49854, 4 hits
SSF50494 SSF50494, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01180 CUB, 3 hits
PS50240 TRYPSIN_DOM, 2 hits
PS00134 TRYPSIN_HIS, 2 hits
PS00135 TRYPSIN_SER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q7RTY7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLLASAGLL LLLVIGHPRS LGLKCGIRMV NMKSKEPAVG SRFFSRISSW
60 70 80 90 100
RNSTVTGHPW QVSLKSDEHH FCGGSLIQED RVVTAAHCLD SLSEKQLKNI
110 120 130 140 150
TVTSGEYSLF QKDKQEQNIP VSKIITHPEY NSREYMSPDI ALLYLKHKVK
160 170 180 190 200
FGNAVQPICL PDSDDKVEPG ILCLSSGWGK ISKTSEYSNV LQEMELPIMD
210 220 230 240 250
DRACNTVLKS MNLPPLGRTM LCAGFPDWGM DACQGDSGGP LVCRRGGGIW
260 270 280 290 300
ILAGITSWVA GCAGGSVPVR NNHVKASLGI FSKVSELMDF ITQNLFTGLD
310 320 330 340 350
RGQPLSKVGS RYITKALSSV QEVNGSQRGK GILDMEKQVG CDHDYVSLRS
360 370 380 390 400
SSGVLFNQRS LMEDDGKQNK RVCGKILPSP LLAETSEAMV PFVSDTEDSG
410 420 430 440 450
SGFELTVTAV QKSEAGSGCG SLAILVEEGT NHSAKYPDLY PSNIRCHWFI
460 470 480 490 500
CAPEKHIIKL TFEDFAVKFS PNCIYDAVVI YGDSEEKHKL AKLCGMLTIT
510 520 530 540 550
SIFSSSNMTV IYFKSDGKNR LQGFKARFTI LPSESLNKFE PKLPPQNNPV
560 570 580 590 600
STVKAILHDV CGIPPFSPQW LSRRIAGGEE ACPHCWPWQV GLRFLGDYQC
610 620 630 640 650
GGAIINPVWI LTAAHCVQLK NNPLSWTIIA GDHDRNLKES TEQVRRAKHI
660 670 680 690 700
IVHEDFNTLS YDSDIALIQL SSPLEYNSVV RPVCLPHSAE PLFSSEICAV
710 720 730 740 750
TGWGSISADG GLASRLQQIQ VHVLEREVCE HTYYSAHPGG ITEKMICAGF
760 770 780 790 800
AASGEKDFCQ GDSGGPLVCR HENGPFVLYG IVSWGAGCVQ PWKPGVFARV
810 820 830 840 850
MIFLDWIQSK INGPASLQTN NKCKTLKQQL PPPTPSPDSA SWPGCCSEAE
860 870 880 890 900
LEKPRGFFPT PRYLLDYRGR LECSWVLRVS PSSMAKFTIE YLSLLGSPVC
910 920 930 940 950
QDSVLIIYEE RHSKRKTAGG LHGRRLYSMT FMSPGPLVRV TFHALVRGAF
960 970 980 990 1000
GISYIDLKVL GPKDSKITRL SQSSNREHLV PCEDVLLTKP EGIMQIPRNS
1010 1020 1030 1040 1050
HRTTMGCQWR LVAPLNHIIQ LNIINFPMKP TTFVCHGHLR VYEGFGPGKK
1060 1070 1080 1090 1100
LIASFAGTLA MILTKDILKR EKLNFINTYI MHIWENSVYD NVRSVGKRKQ
1110 1120 1130
KKFASNLSYS MEAEKSRIQV PADLVPAKGS LSGS
Length:1,134
Mass (Da):125,066
Last modified:November 28, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i87F935BCCB773B16
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YGY6H0YGY6_HUMAN
Ovochymase-1
OVCH1
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YH00H0YH00_HUMAN
Ovochymase-1
OVCH1
80Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_029089133R → C. Corresponds to variant dbSNP:rs10843438Ensembl.1
Natural variantiVAR_029090228W → G. Corresponds to variant dbSNP:rs967181Ensembl.1
Natural variantiVAR_029091330K → E. Corresponds to variant dbSNP:rs3847680Ensembl.1
Natural variantiVAR_029092444I → T. Corresponds to variant dbSNP:rs7975356Ensembl.1
Natural variantiVAR_057159557L → V. Corresponds to variant dbSNP:rs35183403Ensembl.1
Natural variantiVAR_029093672S → F. Corresponds to variant dbSNP:rs11050243Ensembl.1
Natural variantiVAR_029094754G → R. Corresponds to variant dbSNP:rs12305672Ensembl.1
Natural variantiVAR_029095881P → A. Corresponds to variant dbSNP:rs1347570Ensembl.1
Natural variantiVAR_029096934P → S. Corresponds to variant dbSNP:rs7967676Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC012151 Genomic DNA No translation available.
BN000128 mRNA Translation: CAD67579.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.674588

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000318184; ENSP00000326708; ENSG00000187950

UCSC genome browser

More...
UCSCi
uc001rix.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012151 Genomic DNA No translation available.
BN000128 mRNA Translation: CAD67579.1
UniGeneiHs.674588

3D structure databases

ProteinModelPortaliQ7RTY7
SMRiQ7RTY7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ7RTY7, 3 interactors
STRINGi9606.ENSP00000326708

Protein family/group databases

MEROPSiS01.322

PTM databases

iPTMnetiQ7RTY7
PhosphoSitePlusiQ7RTY7

Polymorphism and mutation databases

BioMutaiOVCH1
DMDMi118573093

Proteomic databases

PaxDbiQ7RTY7
PeptideAtlasiQ7RTY7
PRIDEiQ7RTY7
ProteomicsDBi68936

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
341350
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000318184; ENSP00000326708; ENSG00000187950
UCSCiuc001rix.2 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000187950.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
OVCH1
HGNCiHGNC:23080 OVCH1
HPAiHPA040253
neXtProtiNX_Q7RTY7
PharmGKBiPA134910581

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
HOGENOMiHOG000172098
InParanoidiQ7RTY7
OrthoDBi1314811at2759
PhylomeDBiQ7RTY7
TreeFamiTF318987

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
341350

Protein Ontology

More...
PROi
PR:Q7RTY7

Gene expression databases

BgeeiENSG00000187950 Expressed in 77 organ(s), highest expression level in right lung
ExpressionAtlasiQ7RTY7 baseline and differential

Family and domain databases

CDDicd00041 CUB, 3 hits
cd00190 Tryp_SPc, 2 hits
Gene3Di2.60.120.290, 3 hits
InterProiView protein in InterPro
IPR000859 CUB_dom
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR035914 Sperma_CUB_dom_sf
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00431 CUB, 2 hits
PF00089 Trypsin, 2 hits
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00042 CUB, 2 hits
SM00020 Tryp_SPc, 2 hits
SUPFAMiSSF49854 SSF49854, 4 hits
SSF50494 SSF50494, 2 hits
PROSITEiView protein in PROSITE
PS01180 CUB, 3 hits
PS50240 TRYPSIN_DOM, 2 hits
PS00134 TRYPSIN_HIS, 2 hits
PS00135 TRYPSIN_SER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOVCH1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7RTY7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 28, 2006
Last modified: February 13, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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