Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein SSX8

Gene

SSX8

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Could act as a modulator of transcription.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SSX8
Gene namesi
Name:SSX8
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:19654 SSX8
MIMi300543 gene
neXtProtiNX_Q7RTT4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi158518620

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002278121 – 187Protein SSX8Add BLAST187

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei123PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PeptideAtlasiQ7RTT4
PRIDEiQ7RTT4
ProteomicsDBi68899

Expressioni

Tissue specificityi

Not detected in any normal or tumor tissues.1 Publication

Organism-specific databases

HPAiHPA045683

Structurei

3D structure databases

ProteinModelPortaliQ7RTT4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 83KRAB-relatedPROSITE-ProRule annotationAdd BLAST64

Sequence similaritiesi

Belongs to the SSX family.Curated

Phylogenomic databases

HOVERGENiHBG002056
InParanoidiQ7RTT4
PhylomeDBiQ7RTT4

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003655 Krueppel-associated_box-rel
IPR028804 SSX
IPR019041 SSXRD_motif
PANTHERiPTHR14112 PTHR14112, 1 hit
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF09514 SSXRD, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SUPFAMiSSF109640 SSF109640, 1 hit
PROSITEiView protein in PROSITE
PS50806 KRAB_RELATED, 1 hit

Sequencei

Sequence statusi: Complete.

Q7RTT4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNGDDAFAKR PRDDDKASEK RSKAFNDIAT YFSKKEWEKM KYSEKISYVY
60 70 80 90 100
MKRNYEAMTK LGFNVTLPPF MCNKQATDFQ GNYFDNDRNR RIQVERPQMT
110 120 130 140 150
FGRLQRIIPK IMPKKPAEEG NDSKGVSEAS GPQNDGKQLA PGKANTSEKI
160 170 180
NKRSGPKRGR HAWTHRLRER NQLVIYEEIR DPEEDDE
Length:187
Mass (Da):21,859
Last modified:September 11, 2007 - v2
Checksum:i710F1FEAEEFD4DD1
GO

Sequence cautioni

The sequence DAA00375 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL450023 Genomic DNA No translation available.
BK000688 Genomic DNA Translation: DAA00375.1 Sequence problems.
UniGeneiHs.694472

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL450023 Genomic DNA No translation available.
BK000688 Genomic DNA Translation: DAA00375.1 Sequence problems.
UniGeneiHs.694472

3D structure databases

ProteinModelPortaliQ7RTT4
ModBaseiSearch...
MobiDBiSearch...

Polymorphism and mutation databases

DMDMi158518620

Proteomic databases

PeptideAtlasiQ7RTT4
PRIDEiQ7RTT4
ProteomicsDBi68899

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiSSX8
H-InvDBiHIX0056282
HIX0056286
HGNCiHGNC:19654 SSX8
HPAiHPA045683
MIMi300543 gene
neXtProtiNX_Q7RTT4
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG002056
InParanoidiQ7RTT4
PhylomeDBiQ7RTT4

Miscellaneous databases

PROiPR:Q7RTT4
SOURCEiSearch...

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003655 Krueppel-associated_box-rel
IPR028804 SSX
IPR019041 SSXRD_motif
PANTHERiPTHR14112 PTHR14112, 1 hit
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF09514 SSXRD, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SUPFAMiSSF109640 SSF109640, 1 hit
PROSITEiView protein in PROSITE
PS50806 KRAB_RELATED, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSSX8_HUMAN
AccessioniPrimary (citable) accession number: Q7RTT4
Secondary accession number(s): A6NJM6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: September 11, 2007
Last modified: November 7, 2018
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again