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Protein

DNA ligase

Gene

PY01533

Organism
Plasmodium yoelii yoelii
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PY01533Imported
OrganismiPlasmodium yoelii yoeliiImported
Taxonomic identifieri73239 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Vinckeia)
Proteomesi
  • UP000008553 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiPlasmoDB:PY01533

Interactioni

Protein-protein interaction databases

STRINGi352914.XP_729309.1

Structurei

3D structure databases

ProteinModelPortaliQ7RPC6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini556 – 692DNA_LIGASE_A3InterPro annotationAdd BLAST137

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili802 – 822Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiQ7RPC6
OMAiWIKYKRD

Family and domain databases

Gene3Di1.10.3260.10, 2 hits
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

Q7RPC6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGDEQCDTK IEESHVKSEE KEASKRKNTN DDGAKTKKSK VKNENEIKKG
60 70 80 90 100
SLFNCKVYED EKISDLSSPK FNPANFDISN LCLSEKDKIK HKFKDSLLFT
110 120 130 140 150
FLTNTFNQIE ELKGSGAGSK KNVAIILSNV FRVLIYYSPN DLIPAVYITL
160 170 180 190 200
NKVAPDYQNV EAGVGEALIL KTMSEAYSRT EASIKKDLQQ IEDLGIIAES
210 220 230 240 250
CSCKMRTIFP LPRLTIQSVF NELKSIPNIS GSNSQQKKRE VIKKLLVSAK
260 270 280 290 300
TSEAKYIVRF LQQRLRIGVN SATVLQALAY AFVLTRPEIP ENIIKDGKMM
310 320 330 340 350
NEKLLNERIV VKGDKDNCDD DATEVKNENN IKLEKTNDTD NKTNVLDTDQ
360 370 380 390 400
FNNLVKSIKI RNERMSKPNL FFNIGKEGDT RLLPIFKELK NAYCDINNDS
410 420 430 440 450
DIFECMEKSV KSALCELPNI EMIIQNLLSG DDMNVLMKKC TVKTGVPVQP
460 470 480 490 500
MLAKPTKGIQ EVLDRFNNVT FTCEYKYDGE RAQIHYIDKD NIKIFSRNLE
510 520 530 540 550
TMTEKYPDVI QIVKDQIMPG VTESIIDSEV VAYDIENKKI LPFQILTTRK
560 570 580 590 600
RKDVDIENIK VKICLFPFDL ICCNGVPVIK EPLEIRRKLL YSLLRCKEGV
610 620 630 640 650
LEYATHSEMN NIDDIDIFLQ DAIENNCEGL MVKTLLDNAS YEPSRRSLNW
660 670 680 690 700
LKVKKDYIEG LSDSVDLVPI AGYYGKGKRS GVYGAFVLAA YNSETENFQT
710 720 730 740 750
VCKAGTGFSD EILNALHESL SDKIIPNKKS YYEVSDKLNP DVWFDAHYVW
760 770 780 790 800
EIKAADLSLS PVHTAAIGVY SDDKGIGLRF PRFLRLRDDK NPEQATTAQQ
810 820
IVEFYEAQFA SNKNKNNNYN DESGSE
Length:826
Mass (Da):93,736
Last modified:December 15, 2003 - v1
Checksum:i32E37316CE828FAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABL01000407 Genomic DNA Translation: EAA20874.1

Genome annotation databases

EnsemblProtistsiEAA20874; EAA20874; EAA20874

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABL01000407 Genomic DNA Translation: EAA20874.1

3D structure databases

ProteinModelPortaliQ7RPC6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi352914.XP_729309.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAA20874; EAA20874; EAA20874

Organism-specific databases

EuPathDBiPlasmoDB:PY01533

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiQ7RPC6
OMAiWIKYKRD

Family and domain databases

Gene3Di1.10.3260.10, 2 hits
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ7RPC6_PLAYO
AccessioniPrimary (citable) accession number: Q7RPC6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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