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Entry version 85 (31 Jul 2019)
Sequence version 4 (23 Oct 2007)
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Protein
Submitted name:

AGAP000328-PA

Gene

1271931

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AGAP000328-PAImported
Submitted name:
AMME syndrome candidate gene 1 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:1271931Imported
ORF Names:AgaP_AGAP000328Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnopheles gambiae (African malaria mosquito)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7165 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007062 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7165.AGAP000328-PA

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini108 – 302AMMECR1InterPro annotationAdd BLAST195

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 109DisorderedSequence analysisAdd BLAST109

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3274 Eukaryota
COG2078 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000223418

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q7QF70

Identification of Orthologs from Complete Genome Data

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OMAi
CIGCLTP

Database of Orthologous Groups

More...
OrthoDBi
1274811at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7QF70

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.30.700.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023473 AMMECR1
IPR036071 AMMECR1_dom_sf
IPR002733 AMMECR1_domain
IPR027485 AMMECR1_N

The PANTHER Classification System

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PANTHERi
PTHR13016 PTHR13016, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF01871 AMMECR1, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF143447 SSF143447, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00296 TIGR00296, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS51112 AMMECR1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7QF70-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSSCCGTKK QKLNGNYSSA NGYSTTGTNN AGPQRNGIAD AGGAAQNNHN
60 70 80 90 100
SYHGRGGGAA GQQSQQQQHQ HQQHQQQLSS SSSSSSSSSS GYNGYMVNGH
110 120 130 140 150
GNHHLSQQQS SMIGSMPDMC FYCFEVLYRE LHNLEEPRTP CFTNDPFPLF
160 170 180 190 200
VTWKIGKDKR LRGCIGTFSA MRLHSGLREY AITSALRDSR FSPITRDEIQ
210 220 230 240 250
RLTVSVSILQ GFEEARGYLD WTLGIHGIRI EFYNERGSKR TATYLPQVAT
260 270 280 290 300
EQGWDQTQTI DSLLRKGGYR AQITPETRRS IKLTRYTSQE CQMSYSEYRE
310
LLEKQSHYHG QLCKMQC
Length:317
Mass (Da):35,585
Last modified:October 23, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBA16CA4DD776E93A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAAB01008846 Genomic DNA Translation: EAA06185.4

NCBI Reference Sequences

More...
RefSeqi
XP_310788.4, XM_310788.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
AGAP000328-RA; AGAP000328-PA; AGAP000328

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1271931

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
aga:AgaP_AGAP000328

Bioinformatics Resource for Invertebrate Vectors of Human Pathogens

More...
VectorBasei
AGAP000328-RA; AGAP000328-PA; AGAP000328

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008846 Genomic DNA Translation: EAA06185.4
RefSeqiXP_310788.4, XM_310788.5

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7165.AGAP000328-PA

Genome annotation databases

EnsemblMetazoaiAGAP000328-RA; AGAP000328-PA; AGAP000328
GeneIDi1271931
KEGGiaga:AgaP_AGAP000328
VectorBaseiAGAP000328-RA; AGAP000328-PA; AGAP000328

Phylogenomic databases

eggNOGiKOG3274 Eukaryota
COG2078 LUCA
HOGENOMiHOG000223418
InParanoidiQ7QF70
OMAiCIGCLTP
OrthoDBi1274811at2759
PhylomeDBiQ7QF70

Family and domain databases

Gene3Di3.30.700.20, 1 hit
InterProiView protein in InterPro
IPR023473 AMMECR1
IPR036071 AMMECR1_dom_sf
IPR002733 AMMECR1_domain
IPR027485 AMMECR1_N
PANTHERiPTHR13016 PTHR13016, 1 hit
PfamiView protein in Pfam
PF01871 AMMECR1, 1 hit
SUPFAMiSSF143447 SSF143447, 1 hit
TIGRFAMsiTIGR00296 TIGR00296, 1 hit
PROSITEiView protein in PROSITE
PS51112 AMMECR1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ7QF70_ANOGA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7QF70
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: July 31, 2019
This is version 85 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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