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Protein

Importin subunit alpha

Gene

1276102

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Importin subunit alphaUniRule annotation
Gene namesi
Name:1276102Imported
ORF Names:AgaP_AGAP005401Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 2L

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP005401-PA

Structurei

3D structure databases

ProteinModelPortaliQ7Q7B4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 53IBBInterPro annotationAdd BLAST53
Repeati113 – 156ARMPROSITE-ProRule annotationAdd BLAST44
Repeati156 – 184ARMPROSITE-ProRule annotationAdd BLAST29
Repeati325 – 359ARMPROSITE-ProRule annotationAdd BLAST35

Sequence similaritiesi

Belongs to the importin alpha family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0166 Eukaryota
COG5064 LUCA
HOGENOMiHOG000167616
InParanoidiQ7Q7B4
OMAiPYAITIE
OrthoDBiEOG091G095Z
PhylomeDBiQ7Q7B4

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 3 hits
PS51214 IBB, 1 hit

Sequencei

Sequence statusi: Complete.

Q7Q7B4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNATHRHRY KNVGLDSTEM RRRREEEGIQ LRKQKREQQL IKRRNVNVAD
60 70 80 90 100
ELEQDAILSD ETTSTDNRSL IQPAVIQALY SENIEEQLVA TQKFRRLLSK
110 120 130 140 150
EPNPPIDMVI KHNIVPRLVQ FLGNSENSTL QFEAAWALTN IASGTSEQTS
160 170 180 190 200
VVIAAGAVPI FVDLMKSPHE DVQEQAIWAL GNIAGDSPEC RDCVLDHDVL
210 220 230 240 250
EPLLHVLSTS RRLTLTRNAV WALSNMCRGK NPPPDFSKVE KCLPILSQLM
260 270 280 290 300
FHNDVEVLGD AVWAVSYLSD GSNDNIQAVI DAGCCRRLIE LLSHSHNNVV
310 320 330 340 350
SAALRAVGNI VTGNDTQTQL ILNCNALPSI LQLLSSTKEA VRKEACWTIS
360 370 380 390 400
NIAAGNRNQI QAAIDANIFP SIIDLLQKAD FKTRKEAAWA ITNATSGGTV
410 420 430 440 450
QQIKYLVDAG CIPPMCELLT VMDPKIVTVA LNGLENILKV GDEQRTKPNP
460 470 480 490 500
YAVMIEECYG LDKLEFLQSH QNNDIYEKAF SIIQKYFSND DEDLAVAPST
510 520
DNNQFQFNAD QSVPMDGFQF
Length:520
Mass (Da):57,893
Last modified:October 23, 2007 - v4
Checksum:iC901A417981515CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008960 Genomic DNA Translation: EAA11775.4
RefSeqiXP_315411.4, XM_315411.4

Genome annotation databases

EnsemblMetazoaiAGAP005401-RA; AGAP005401-PA; AGAP005401
GeneIDi1276102
KEGGiaga:AgaP_AGAP005401
VectorBaseiAGAP005401-RA; AGAP005401-PA; AGAP005401

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008960 Genomic DNA Translation: EAA11775.4
RefSeqiXP_315411.4, XM_315411.4

3D structure databases

ProteinModelPortaliQ7Q7B4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7165.AGAP005401-PA

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAGAP005401-RA; AGAP005401-PA; AGAP005401
GeneIDi1276102
KEGGiaga:AgaP_AGAP005401
VectorBaseiAGAP005401-RA; AGAP005401-PA; AGAP005401

Phylogenomic databases

eggNOGiKOG0166 Eukaryota
COG5064 LUCA
HOGENOMiHOG000167616
InParanoidiQ7Q7B4
OMAiPYAITIE
OrthoDBiEOG091G095Z
PhylomeDBiQ7Q7B4

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 3 hits
PS51214 IBB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ7Q7B4_ANOGA
AccessioniPrimary (citable) accession number: Q7Q7B4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 102 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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