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Protein

Transaldolase

Gene

tal

Organism
Gloeobacter violaceus (strain PCC 7421)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.By similarity

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal), Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei136Schiff-base intermediate with substrateBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi343 – 3541Sequence analysisAdd BLAST12
Calcium bindingi366 – 3772Sequence analysisAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandCalcium, Metal-binding, Schiff base

Enzyme and pathway databases

BioCyciGVIO251221:G1G3K-1618-MONOMER
UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
Transaldolase (EC:2.2.1.2)
Gene namesi
Name:tal
Ordered Locus Names:gll1597
OrganismiGloeobacter violaceus (strain PCC 7421)
Taxonomic identifieri251221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaGloeobacteriaGloeobacteralesGloeobacteraceaeGloeobacter
Proteomesi
  • UP000000557 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001735971 – 389TransaldolaseAdd BLAST389

Proteomic databases

PRIDEiQ7NK81

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi251221.gll1597

Structurei

3D structure databases

ProteinModelPortaliQ7NK81
SMRiQ7NK81
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini330 – 365EF-hand 1Add BLAST36
Domaini365 – 388EF-hand 2Add BLAST24

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CW3 Bacteria
COG0176 LUCA
HOGENOMiHOG000281234
InParanoidiQ7NK81
KOiK00616
OMAiMAFDKLH
OrthoDBiPOG091H05RO
PhylomeDBiQ7NK81

Family and domain databases

CDDicd00051 EFh, 1 hit
cd00957 Transaldolase_TalAB, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00492 Transaldolase_1, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR001585 TAL/FSA
IPR004730 Transaldolase_1
IPR018225 Transaldolase_AS
PANTHERiPTHR10683 PTHR10683, 1 hit
PTHR10683:SF20 PTHR10683:SF20, 1 hit
PfamiView protein in Pfam
PF00036 EF-hand_1, 1 hit
PF13202 EF-hand_5, 1 hit
PF00923 TAL_FSA, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 2 hits
SUPFAMiSSF47473 SSF47473, 1 hit
TIGRFAMsiTIGR00874 talAB, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 2 hits
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7NK81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGSLLDQLR QMTIVVADTG DIQAIEQFTP RDATTNPSLI TAAAQMPQYQ
60 70 80 90 100
QIVDDTLKQA RAELGPEAKA AAVATLAFDR LAVAFGLKIL AIVPGRVSTE
110 120 130 140 150
VDARLSYDTE ATIEKGRSLI AQYEAAGISR ERVLIKIAST WEGIRAAEIL
160 170 180 190 200
EDEGIHCNLT LLFGVHQAIA CAEAGVTLIS PFVGRILDWY KKETGRDYEP
210 220 230 240 250
HEDPGVVSVT TIYNYYKKFG YQTQVMGASF RNIGEIVELA GCDLLTISPK
260 270 280 290 300
LLEQLQATDA ELVRKLDPDQ AAGLEIEKID MDQATFEKRH AEDRMASEKL
310 320 330 340 350
DEGIKGFTNA LVALEKLLAD RLARLEGEVA LNQAFESIFR TFDLDGDGFI
360 370 380
TREEWMGTDA VFDAIDLNHD GKITAEELGA GIGAVSKLA
Length:389
Mass (Da):42,513
Last modified:December 15, 2003 - v1
Checksum:i0EE6F75AEC61BBBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000045 Genomic DNA Translation: BAC89538.1
RefSeqiNP_924543.1, NC_005125.1
WP_011141596.1, NC_005125.1

Genome annotation databases

EnsemblBacteriaiBAC89538; BAC89538; BAC89538
GeneIDi2598563
KEGGigvi:gll1597
PATRICifig|251221.4.peg.1634

Similar proteinsi

Entry informationi

Entry nameiTAL_GLOVI
AccessioniPrimary (citable) accession number: Q7NK81
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 15, 2003
Last modified: February 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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