Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - Q7MVY0 (HCP_PORGI)

Entry version 114 (25 May 2022)
Sequence version 1 (15 Dec 2003)
Previous versions | rss
Add a publicationFeedback
Protein

Hydroxylamine reductase

Gene

hcp

Organism
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the reduction of hydroxylamine to form NH3 and H2O.

UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi7Iron-sulfur (4Fe-4S)UniRule annotation1
Metal bindingi10Iron-sulfur (4Fe-4S)UniRule annotation1
Metal bindingi19Iron-sulfur (4Fe-4S)UniRule annotation1
Metal bindingi25Iron-sulfur (4Fe-4S)UniRule annotation1
Metal bindingi244Iron-oxo-sulfur (4Fe-2O-2S); via tele nitrogenUniRule annotation1
Metal bindingi268Iron-oxo-sulfur (4Fe-2O-2S)UniRule annotation1
Metal bindingi312Iron-oxo-sulfur (4Fe-2O-2S)UniRule annotation1
Metal bindingi405Iron-oxo-sulfur (4Fe-2O-2S); via persulfide groupUniRule annotation1
Metal bindingi433Iron-oxo-sulfur (4Fe-2O-2S)UniRule annotation1
Metal bindingi458Iron-oxo-sulfur (4Fe-2O-2S)UniRule annotation1
Metal bindingi493Iron-oxo-sulfur (4Fe-2O-2S)UniRule annotation1
Metal bindingi495Iron-oxo-sulfur (4Fe-2O-2S)UniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		1.7.1.10, 756

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Hydroxylamine reductaseUniRule annotation (EC:1.7.99.1UniRule annotation)
Alternative name(s):
Hybrid-cluster proteinUniRule annotation
Short name:
HCPUniRule annotation
Prismane proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:hcpUniRule annotation
Ordered Locus Names:PG_0893
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPorphyromonas gingivalis (strain ATCC BAA-308 / W83)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri242619 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000588 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001516791 – 550Hydroxylamine reductaseAdd BLAST550

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei405Cysteine persulfideUniRule annotation1

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		242619.PG_0893

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q7MVY0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q7MVY0

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the HCP family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG1151, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_038344_2_0_10

Identification of Orthologs from Complete Genome Data

More...OMAi		CAYAQGM

Database of Orthologous Groups

More...OrthoDBi		337713at2

Family and domain databases

Conserved Domains Database

More...CDDi		cd01914, HCP, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.1270.20, 2 hits
3.40.50.2030, 2 hits

HAMAP database of protein families

More...HAMAPi		MF_00069, Hydroxylam_reduct, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004137, HCP/CODH
IPR010048, Hydroxylam_reduct
IPR016099, Prismane-like_a/b-sand
IPR011254, Prismane-like_sf
IPR016100, Prismane_a-bundle

The PANTHER Classification System

More...PANTHERi		PTHR30109, PTHR30109, 1 hit
PTHR30109:SF0, PTHR30109:SF0, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03063, Prismane, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF000076, HCP, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF56821, SSF56821, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01703, hybrid_clust, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7MVY0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKKMFCYQC QETAGNKGCI LKGVCGKDFS TANLMDLLVF NLKGIAIIMT 
        60         70         80         90        100
SMRRAGVKAD YRKADKAIME SLFATITNAN FDYSSIAKRV EKTFALKAEL 
       110        120        130        140        150
YSLAFTQGIE LPENEAVTMQ GKPEEYDRLA LSVGILRETD EDVRSLKELT 
       160        170        180        190        200
IYGLKGLAAY AEHADRLGYV DEEINAFTER ALHDVTMGLL SAEELTALVL 
       210        220        230        240        250
ETGSFGVKVM ALLDKANTET YGNPEITEVN IGVGSRPGIL ISGHDLKDME 
       260        270        280        290        300
MLLEQTEGTG IDVYTHGEML PANYYPKFKK YNHFFGNYGN AWWKQREEFE 
       310        320        330        340        350
TFNGPILFTT NCIVPPKANA SYKDRVFTTN ATGYPGFKYI ESDQHGRKDF 
       360        370        380        390        400
SEIIALAKTC QPPTEIESGT IIGGFAHHQV LSIADKVVEA VSSGAIRKFV 
       410        420        430        440        450
VMSGCDGRQS GRNYYTEFAE ALPSDTVILT SGCAKFRYNK LQLGDIGGIP 
       460        470        480        490        500
RVLDAGQCND SYSLAVIALK LKEVMGLDDI NKLPIVYNIA WYEQKAVIVL 
       510        520        530        540        550
LALLSLGVKN IHVGPTLPAF LSPNVAKVLI ENFGIAGIGT VEEDIRTLIA
Length:550
Mass (Da):60,529
Last modified:December 15, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6695227AC38ED89D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE015924 Genomic DNA Translation: AAQ66036.1

NCBI Reference Sequences

More...RefSeqi		WP_005875197.1, NC_002950.2

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAQ66036; AAQ66036; PG_0893

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		pgi:PG_0893

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|242619.8.peg.826

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015924 Genomic DNA Translation: AAQ66036.1
RefSeqiWP_005875197.1, NC_002950.2

3D structure databases

AlphaFoldDBiQ7MVY0
SMRiQ7MVY0
ModBaseiSearch...

Protein-protein interaction databases

STRINGi242619.PG_0893

Genome annotation databases

EnsemblBacteriaiAAQ66036; AAQ66036; PG_0893
KEGGipgi:PG_0893
PATRICifig|242619.8.peg.826

Phylogenomic databases

eggNOGiCOG1151, Bacteria
HOGENOMiCLU_038344_2_0_10
OMAiCAYAQGM
OrthoDBi337713at2

Enzyme and pathway databases

BRENDAi1.7.1.10, 756

Family and domain databases

CDDicd01914, HCP, 1 hit
Gene3Di1.20.1270.20, 2 hits
3.40.50.2030, 2 hits
HAMAPiMF_00069, Hydroxylam_reduct, 1 hit
InterProiView protein in InterPro
IPR004137, HCP/CODH
IPR010048, Hydroxylam_reduct
IPR016099, Prismane-like_a/b-sand
IPR011254, Prismane-like_sf
IPR016100, Prismane_a-bundle
PANTHERiPTHR30109, PTHR30109, 1 hit
PTHR30109:SF0, PTHR30109:SF0, 1 hit
PfamiView protein in Pfam
PF03063, Prismane, 1 hit
PIRSFiPIRSF000076, HCP, 1 hit
SUPFAMiSSF56821, SSF56821, 1 hit
TIGRFAMsiTIGR01703, hybrid_clust, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHCP_PORGI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7MVY0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: December 15, 2003
Last modified: May 25, 2022
This is version 114 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again