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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Vibrio vulnificus (strain YJ016)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei12NucleophileUniRule annotation1
Metal bindingi12MagnesiumUniRule annotation1
Metal bindingi14Magnesium; via carbonyl oxygenUniRule annotation1
Active sitei54Schiff-base intermediate with substrateUniRule annotation1
Metal bindingi188MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium, Metal-binding, Schiff base

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
Ordered Locus Names:VVA0474
OrganismiVibrio vulnificus (strain YJ016)
Taxonomic identifieri196600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002675 Componenti: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002846061 – 271Phosphonoacetaldehyde hydrolaseAdd BLAST271

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ7MF46
SMRiQ7MF46
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000217971
KOiK05306
OMAiKAVIFDW
OrthoDBiPOG091H05HY

Family and domain databases

CDDicd02586 HAD_PHN, 1 hit
Gene3Di1.10.150.240, 1 hit
3.40.50.1000, 2 hits
HAMAPiMF_01375 PhnX, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR023214 HAD_sf
IPR023198 PGP-like_dom2
IPR006323 Phosphonoacetald_hydro
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01509 HAD-SF-IA-v3, 1 hit
TIGR01422 phosphonatase, 1 hit

Sequencei

Sequence statusi: Complete.

Q7MF46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKSPIQAVI FDWAGTIVDF GSFAPTSIFV EAFKQGFDFE IDLEEAREPM
60 70 80 90 100
GLGKWDHIQA VGRIPAVDKR WNEKFGRSMI SEDIDAIYAA FMPLQKAKVA
110 120 130 140 150
DHAEPILNAI EVVNGLKDKG IKIGSCSGYP REVMDVLIPV AADYGYQPDY
160 170 180 190 200
VVATDDLPQG GRPAPFMALK NVIELGVSDV KACVKVDDSA PGIFEGHNAG
210 220 230 240 250
MWTVGLLLSG NEAGLTFEEY QAADEATLEK AREKARAKLL KSSPHYLIDT
260 270
IADFPEVVAD IERRLAAGER P
Length:271
Mass (Da):29,617
Last modified:April 17, 2007 - v2
Checksum:i820603F976FD7878
GO

Sequence cautioni

The sequence BAC96500 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000038 Genomic DNA Translation: BAC96500.1 Different initiation.
RefSeqiWP_011082503.1, NC_005140.1

Genome annotation databases

EnsemblBacteriaiBAC96500; BAC96500; BAC96500
GeneIDi2621241
KEGGivvy:VVA0474
PATRICifig|196600.6.peg.3677

Similar proteinsi

Entry informationi

Entry nameiPHNX_VIBVY
AccessioniPrimary (citable) accession number: Q7MF46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: March 28, 2018
This is version 93 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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