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Protein

Taste receptor type 2

Gene

Tas2r131

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • detection of chemical stimulus involved in sensory perception of bitter taste Source: GO_Central

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processSensory transduction, TasteUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-418594 G alpha (i) signalling events
R-MMU-420499 Class C/3 (Metabotropic glutamate/pheromone receptors)

Names & Taxonomyi

Protein namesi
Recommended name:
Taste receptor type 2UniRule annotation
Gene namesi
Name:Tas2r131Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:2681280 Tas2r131

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 24HelicalSequence analysisAdd BLAST19
Transmembranei36 – 60HelicalSequence analysisAdd BLAST25
Transmembranei80 – 102HelicalSequence analysisAdd BLAST23
Transmembranei122 – 140HelicalSequence analysisAdd BLAST19
Transmembranei178 – 199HelicalSequence analysisAdd BLAST22
Transmembranei226 – 251HelicalSequence analysisAdd BLAST26
Transmembranei257 – 277HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000057699 Expressed in 1 organ(s), highest expression level in lung

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000080736

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 236G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST221

Sequence similaritiesi

Belongs to the G-protein coupled receptor T2R family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410JAUJ Eukaryota
ENOG41117W6 LUCA
GeneTreeiENSGT00760000119096
HOVERGENiHBG060698
KOiK08474
OMAiTTWLATC
OrthoDBiEOG091G0G0Q
TreeFamiTF335891

Family and domain databases

InterProiView protein in InterPro
IPR017452 GPCR_Rhodpsn_7TM
IPR007960 T2R
PfamiView protein in Pfam
PF05296 TAS2R, 1 hit
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7M708-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYMILVRAVF ITGMLGNMFI GLANCSDWVK NQKITFINFI MVCLAASRIS
60 70 80 90 100
SVLMLFIDAT IQELAPHFYY SYRLVKCSDI FWVITDQLST WLATCLSIFY
110 120 130 140 150
LFKVAHISHP LFLWFKWRLR GVLVVFLVFS LFLLISYFLL LETLPIWGDI
160 170 180 190 200
YVTLKNNLTL FSGTIKTTAF QKIIVFDIIY LVPFLVSLAS LLLLFLSLVK
210 220 230 240 250
HSRSLDLIST TSEDSRTKIH KKAMKMLVSF LILFIIHIFF MQLARWLLFL
260 270 280 290 300
FPMSRPINFI LTLNIFALTH SFILILGNSN LRQRAMRILQ HLKSQLQELI
310
LSLHRFSSLY
Length:310
Mass (Da):36,181
Last modified:December 15, 2003 - v1
Checksum:i0A5A4EADEB5767ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151055 Genomic DNA No translation available.
BK001089 Genomic DNA Translation: DAA01228.1
RefSeqiNP_996913.1, NM_207030.1
UniGeneiMm.377917

Genome annotation databases

EnsembliENSMUST00000082085; ENSMUSP00000080736; ENSMUSG00000057699
GeneIDi387356
KEGGimmu:387356
UCSCiuc009ejw.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151055 Genomic DNA No translation available.
BK001089 Genomic DNA Translation: DAA01228.1
RefSeqiNP_996913.1, NM_207030.1
UniGeneiMm.377917

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000080736

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000082085; ENSMUSP00000080736; ENSMUSG00000057699
GeneIDi387356
KEGGimmu:387356
UCSCiuc009ejw.1 mouse

Organism-specific databases

CTDi387356
MGIiMGI:2681280 Tas2r131

Phylogenomic databases

eggNOGiENOG410JAUJ Eukaryota
ENOG41117W6 LUCA
GeneTreeiENSGT00760000119096
HOVERGENiHBG060698
KOiK08474
OMAiTTWLATC
OrthoDBiEOG091G0G0Q
TreeFamiTF335891

Enzyme and pathway databases

ReactomeiR-MMU-418594 G alpha (i) signalling events
R-MMU-420499 Class C/3 (Metabotropic glutamate/pheromone receptors)

Miscellaneous databases

PROiPR:Q7M708
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000057699 Expressed in 1 organ(s), highest expression level in lung

Family and domain databases

InterProiView protein in InterPro
IPR017452 GPCR_Rhodpsn_7TM
IPR007960 T2R
PfamiView protein in Pfam
PF05296 TAS2R, 1 hit
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ7M708_MOUSE
AccessioniPrimary (citable) accession number: Q7M708
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: November 7, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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