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Entry version 123 (11 Dec 2019)
Sequence version 1 (15 Dec 2003)
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Protein

Kinesin-like protein KIF27

Gene

Kif27

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays an essential role in motile ciliogenesis.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi84 – 91ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor protein
Biological processCilium biogenesis/degradation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-MMU-983189 Kinesins

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Kinesin-like protein KIF27
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kif27
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1922300 Kif27

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Microtubule

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003071441 – 1394Kinesin-like protein KIF27Add BLAST1394

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei643PhosphoserineCombined sources1
Modified residuei646PhosphoserineCombined sources1
Modified residuei672PhosphoserineBy similarity1
Modified residuei675PhosphoserineBy similarity1
Modified residuei704PhosphoserineBy similarity1
Modified residuei999PhosphoserineBy similarity1
Modified residuei1365PhosphoserineBy similarity1
Modified residuei1387PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7M6Z4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7M6Z4

PeptideAtlas

More...
PeptideAtlasi
Q7M6Z4

PRoteomics IDEntifications database

More...
PRIDEi
Q7M6Z4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7M6Z4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7M6Z4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000060176 Expressed in 50 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7M6Z4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7M6Z4 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with STK36.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q69ZM62EBI-15765182,EBI-15765145

GO - Molecular functioni

Protein-protein interaction databases

Database of interacting proteins

More...
DIPi
DIP-59753N

Protein interaction database and analysis system

More...
IntActi
Q7M6Z4, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000043304

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7M6Z4 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q7M6Z4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5 – 341Kinesin motorPROSITE-ProRule annotationAdd BLAST337

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili352 – 418Sequence analysisAdd BLAST67
Coiled coili498 – 554Sequence analysisAdd BLAST57
Coiled coili709 – 891Sequence analysisAdd BLAST183
Coiled coili921 – 1078Sequence analysisAdd BLAST158
Coiled coili1118 – 1152Sequence analysisAdd BLAST35
Coiled coili1186 – 1226Sequence analysisAdd BLAST41

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1282 – 1285Poly-Ser4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF27 subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0244 Eukaryota
COG5059 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157487

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000068072

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7M6Z4

KEGG Orthology (KO)

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KOi
K10395

Identification of Orthologs from Complete Genome Data

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OMAi
SVKETCG

Database of Orthologous Groups

More...
OrthoDBi
369179at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7M6Z4

TreeFam database of animal gene trees

More...
TreeFami
TF325946

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR24115 PTHR24115, 2 hits

Pfam protein domain database

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Pfami
View protein in Pfam
PF00225 Kinesin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00380 KINESINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00129 KISc, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7M6Z4-1) [UniParc]FASTAAdd to basket
Also known as: KIF27A

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEEIPIKVAV RIRPLLCKEV LHNHQVCVRD IPNTQQIIIG RDRVFTFDFV
60 70 80 90 100
FGKNSTQDEV YNTCIKPLVL SLIEGYNATV FAYGQTGSGK TYTIGGGHVA
110 120 130 140 150
SVVEGQKGII PRAIQEIFQS ISENPSIDFK IKVSYIEVYK EDLRDLLELE
160 170 180 190 200
TSMKDLHIRE DEKGNTVIVG AKECQVESVE DVMSLLQVGN AARHTGTTQM
210 220 230 240 250
NEHSSRSHAI FTISVCQVEK NAEAAENGEW YSHRHIVSKF HFVDLAGSER
260 270 280 290 300
VTKTGNTGER FKESIQINSG LLALGNVISA LGDPRRKSSH IPYRDAKITR
310 320 330 340 350
LLKDSLGGSA KTVMITCVSP SSSDFDESLN SLKYANRARN IRNKPALNIS
360 370 380 390 400
PQADRMDEME FEIKLLREAL QSHQASISQA SQASSENVPD QNRIHSLEEQ
410 420 430 440 450
VAQLQEECLG YQDCIEQAFA FLVDLKDAVK LNQKQQHKLQ EWFSRTQEVR
460 470 480 490 500
KAVLTPLPGN QGIGNLEEGP QHLTVLQLKR ELKKYQCALA ADQVVFTQKD
510 520 530 540 550
LELEELRTQV QLMMQESKGH AVSLKEAQKV NRLQNEKIIE QQLLVDQLSA
560 570 580 590 600
ELAKRSLSVP TSAKESCGDG PDARASEKRP HTAPFESHWG HYVYIPSRQD
610 620 630 640 650
FKKVCSSTPV YSLDQVFAGF RTRSQMLMGH LEDQDEVLHC QFSDNSDDED
660 670 680 690 700
SEGQEKPRVR SRSHSWAKKP GSVCSLVELS DTQAESQRSY LGNGDLKMES
710 720 730 740 750
LQESQEINLQ KLRTSELILN KAKQKMRELT INIRMKEDLI KELIKTGNNA
760 770 780 790 800
KSVSRQYSLK VTKLEHEAEQ AKVELTETRK QLQELESKDL SDVALKVKLQ
810 820 830 840 850
KEFRKKMDAA KMRVQVLQKK QQDSKKLASL SIQNEKRASE LEHNVDHLKY
860 870 880 890 900
QKVQLQRRLR EEGEKKKQLD AEIKRDQQKI KELQLKAGQG EGLNPKAEDQ
910 920 930 940 950
DGFNLNRRKS PFRSGDQFQK LDEQRKWLDE EVEKVLSQRQ ELEMLEEDLK
960 970 980 990 1000
KREAIVSKKE ALLQEKSLLE NKKLRSSQAL STDGLKISAR LNLLDQELSE
1010 1020 1030 1040 1050
KSLQLESSPT EEKMKISEQV QALQRERDQL QRQRNSVDER LKHGRVLSPK
1060 1070 1080 1090 1100
EEHLLFQLEE GIEALEAAIE FKNESIQSRQ NSLKASFQNL SQSEANVLEK
1110 1120 1130 1140 1150
LVCLNITEIR AILFKYFNKV INLRETERKQ QLQNKEMKMK VLERDNVVHE
1160 1170 1180 1190 1200
LESALEHLRL QCDRRLTLQQ KEHEQKMQLL LQHFKDQDGD SIIETLKNYE
1210 1220 1230 1240 1250
DKIQQLEKDL YFYKKTSRDL KKRLKDPAQG AAQWQRTLTE HHDAGDGVLN
1260 1270 1280 1290 1300
PEETTVLSEE LKWASRTENT KLNGSEREVD NSSSSLKTQP LTQQIPEDGP
1310 1320 1330 1340 1350
DSLPARSSIA PSSGQLQSIA DKTEARPFTH SQSPVPHQFQ PVRSIGPLQG
1360 1370 1380 1390
VKPVKLCRRE LRQISAMELS LRRCSLGAGG RSMTADSLED PEEN
Length:1,394
Mass (Da):158,956
Last modified:December 15, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAC5F7CCD2CA61D6B
GO
Isoform 2 (identifier: Q7M6Z4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-484: Missing.
     485-486: YQ → ML

Show »
Length:910
Mass (Da):104,716
Checksum:i375B4C11BBFAB80D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A286YDI7A0A286YDI7_MOUSE
Kinesin-like protein KIF27
Kif27
144Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1377G → E in BAC28083 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0286071 – 484Missing in isoform 2. 1 PublicationAdd BLAST484
Alternative sequenceiVSP_028608485 – 486YQ → ML in isoform 2. 1 Publication2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC116646 mRNA Translation: AAI16647.1
AK032912 mRNA Translation: BAC28083.1
BK001056 mRNA Translation: DAA01314.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS26570.1 [Q7M6Z4-1]

NCBI Reference Sequences

More...
RefSeqi
NP_780423.2, NM_175214.3 [Q7M6Z4-1]
XP_006517489.1, XM_006517426.3 [Q7M6Z4-1]
XP_006517490.1, XM_006517427.2 [Q7M6Z4-1]
XP_006517492.1, XM_006517429.3 [Q7M6Z4-1]
XP_006517494.1, XM_006517431.2 [Q7M6Z4-1]
XP_006517495.1, XM_006517432.2 [Q7M6Z4-1]
XP_006517496.1, XM_006517433.3 [Q7M6Z4-1]
XP_006517497.1, XM_006517434.2 [Q7M6Z4-1]
XP_006517498.1, XM_006517435.3 [Q7M6Z4-1]
XP_006517499.1, XM_006517436.3 [Q7M6Z4-1]
XP_011242881.1, XM_011244579.2 [Q7M6Z4-1]
XP_011242882.1, XM_011244580.2 [Q7M6Z4-1]
XP_017171108.1, XM_017315619.1 [Q7M6Z4-1]
XP_017171109.1, XM_017315620.1 [Q7M6Z4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000043605; ENSMUSP00000043304; ENSMUSG00000060176 [Q7M6Z4-1]
ENSMUST00000225388; ENSMUSP00000153598; ENSMUSG00000060176 [Q7M6Z4-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
75050

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:75050

UCSC genome browser

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UCSCi
uc007qtq.1 mouse [Q7M6Z4-1]
uc011zao.1 mouse [Q7M6Z4-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116646 mRNA Translation: AAI16647.1
AK032912 mRNA Translation: BAC28083.1
BK001056 mRNA Translation: DAA01314.1
CCDSiCCDS26570.1 [Q7M6Z4-1]
RefSeqiNP_780423.2, NM_175214.3 [Q7M6Z4-1]
XP_006517489.1, XM_006517426.3 [Q7M6Z4-1]
XP_006517490.1, XM_006517427.2 [Q7M6Z4-1]
XP_006517492.1, XM_006517429.3 [Q7M6Z4-1]
XP_006517494.1, XM_006517431.2 [Q7M6Z4-1]
XP_006517495.1, XM_006517432.2 [Q7M6Z4-1]
XP_006517496.1, XM_006517433.3 [Q7M6Z4-1]
XP_006517497.1, XM_006517434.2 [Q7M6Z4-1]
XP_006517498.1, XM_006517435.3 [Q7M6Z4-1]
XP_006517499.1, XM_006517436.3 [Q7M6Z4-1]
XP_011242881.1, XM_011244579.2 [Q7M6Z4-1]
XP_011242882.1, XM_011244580.2 [Q7M6Z4-1]
XP_017171108.1, XM_017315619.1 [Q7M6Z4-1]
XP_017171109.1, XM_017315620.1 [Q7M6Z4-1]

3D structure databases

SMRiQ7M6Z4
ModBaseiSearch...

Protein-protein interaction databases

DIPiDIP-59753N
IntActiQ7M6Z4, 1 interactor
STRINGi10090.ENSMUSP00000043304

PTM databases

iPTMnetiQ7M6Z4
PhosphoSitePlusiQ7M6Z4

Proteomic databases

EPDiQ7M6Z4
PaxDbiQ7M6Z4
PeptideAtlasiQ7M6Z4
PRIDEiQ7M6Z4

Genome annotation databases

EnsembliENSMUST00000043605; ENSMUSP00000043304; ENSMUSG00000060176 [Q7M6Z4-1]
ENSMUST00000225388; ENSMUSP00000153598; ENSMUSG00000060176 [Q7M6Z4-1]
GeneIDi75050
KEGGimmu:75050
UCSCiuc007qtq.1 mouse [Q7M6Z4-1]
uc011zao.1 mouse [Q7M6Z4-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55582
MGIiMGI:1922300 Kif27

Phylogenomic databases

eggNOGiKOG0244 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00940000157487
HOGENOMiHOG000068072
InParanoidiQ7M6Z4
KOiK10395
OMAiSVKETCG
OrthoDBi369179at2759
PhylomeDBiQ7M6Z4
TreeFamiTF325946

Enzyme and pathway databases

ReactomeiR-MMU-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-MMU-983189 Kinesins

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Kif27 mouse

Protein Ontology

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PROi
PR:Q7M6Z4
RNActiQ7M6Z4 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000060176 Expressed in 50 organ(s), highest expression level in testis
ExpressionAtlasiQ7M6Z4 baseline and differential
GenevisibleiQ7M6Z4 MM

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 2 hits
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKIF27_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7M6Z4
Secondary accession number(s): Q14AX5, Q8BMB9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: December 15, 2003
Last modified: December 11, 2019
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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