UniProtKB - Q7M6Y3 (PICAL_MOUSE)
Phosphatidylinositol-binding clathrin assembly protein
Picalm
Functioni
Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells. Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly. Furthermore, regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature. In addition to binding to clathrin, mediates the endocytosis of small R-SNARES (Soluble NSF Attachment Protein REceptors) between plasma membranes and endosomes including VAMP2, VAMP3, VAMP4, VAMP7 or VAMP8. In turn, PICALM-dependent SNARE endocytosis is required for the formation and maturation of autophagic precursors. Modulates thereby autophagy and the turnover of autophagy substrates such as MAPT/TAU or amyloid precursor protein cleaved C-terminal fragment (APP-CTF).
By similarity2 PublicationsGO - Molecular functioni
- 1-phosphatidylinositol binding Source: UniProtKB
- clathrin binding Source: UniProtKB
- clathrin heavy chain binding Source: MGI
- identical protein binding Source: MGI
- low-density lipoprotein particle receptor binding Source: MGI
- phosphatidylinositol-4,5-bisphosphate binding Source: MGI
- SH3 domain binding Source: MGI
- small GTPase binding Source: MGI
- SNARE binding Source: MGI
- tau protein binding Source: MGI
GO - Biological processi
- amyloid-beta clearance by transcytosis Source: ARUK-UCL
- axonogenesis Source: BHF-UCL
- clathrin coat assembly Source: MGI
- clathrin-coated pit assembly Source: MGI
- clathrin-dependent endocytosis Source: Alzheimers_University_of_Toronto
- dendrite morphogenesis Source: BHF-UCL
- endocytosis Source: MGI
- endosomal transport Source: MGI
- hemopoiesis Source: UniProtKB
- iron ion homeostasis Source: Alzheimers_University_of_Toronto
- learning or memory Source: ARUK-UCL
- membrane bending Source: MGI
- modulation of age-related behavioral decline Source: ARUK-UCL
- negative regulation of gene expression Source: Alzheimers_University_of_Toronto
- negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process Source: Alzheimers_University_of_Toronto
- negative regulation of protein localization to cell surface Source: MGI
- negative regulation of protein localization to plasma membrane Source: MGI
- negative regulation of receptor-mediated endocytosis Source: MGI
- positive regulation of amyloid-beta formation Source: Alzheimers_University_of_Toronto
- positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Source: Alzheimers_University_of_Toronto
- positive regulation of axonogenesis Source: MGI
- positive regulation of dendrite extension Source: MGI
- positive regulation of GTPase activity Source: MGI
- positive regulation of neuron death Source: Alzheimers_University_of_Toronto
- positive regulation of synaptic vesicle clustering Source: MGI
- positive regulation of synaptic vesicle endocytosis Source: MGI
- positive regulation of transcription, DNA-templated Source: MGI
- receptor internalization Source: MGI
- receptor-mediated endocytosis Source: UniProtKB
- regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Source: Alzheimers_University_of_Toronto
- regulation of endocytosis Source: MGI
- regulation of protein localization Source: MGI
- regulation of protein transport Source: MGI
- regulation of synaptic vesicle endocytosis Source: MGI
- regulation of synaptic vesicle transport Source: MGI
- regulation of terminal button organization Source: MGI
- regulation of vesicle size Source: MGI
- synaptic vesicle budding from presynaptic endocytic zone membrane Source: GO_Central
- synaptic vesicle endocytosis Source: MGI
- synaptic vesicle maturation Source: Alzheimers_University_of_Toronto
- vesicle budding from membrane Source: MGI
- vesicle cargo loading Source: Alzheimers_University_of_Toronto
- vesicle-mediated transport Source: MGI
Keywordsi
Molecular function | Developmental protein |
Biological process | Endocytosis |
Enzyme and pathway databases
Reactomei | R-MMU-432722, Golgi Associated Vesicle Biogenesis R-MMU-8856825, Cargo recognition for clathrin-mediated endocytosis R-MMU-8856828, Clathrin-mediated endocytosis R-MMU-9696264, RND3 GTPase cycle |
Names & Taxonomyi
Protein namesi | Recommended name: Phosphatidylinositol-binding clathrin assembly proteinAlternative name(s): Clathrin assembly lymphoid myeloid leukemia Short name: CALM |
Gene namesi | Name:Picalm Synonyms:Calm, Fit1 |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2385902, Picalm |
VEuPathDBi | HostDB:ENSMUSG00000039361 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus By similarity
Nucleus
- Nucleus By similarity
Plasma membrane
- Cell membrane By similarity
Other locations
- clathrin-coated pit By similarity
- clathrin-coated vesicle By similarity
Note: Colocalized with clathrin in the Golgi area. Interaction with PIMREG may target PICALM to the nucleus in some cells.By similarity
Endosome
- early endosome Source: MGI
- endosome Source: MGI
Golgi apparatus
- Golgi apparatus Source: UniProtKB-SubCell
Nucleus
- nucleus Source: MGI
Plasma Membrane
- clathrin coat of coated pit Source: MGI
- clathrin-coated pit Source: UniProtKB
- extrinsic component of presynaptic endocytic zone membrane Source: MGI
- plasma membrane Source: MGI
- postsynaptic membrane Source: MGI
- presynaptic membrane Source: MGI
Other locations
- cell surface Source: MGI
- clathrin-coated vesicle Source: MGI
- endosome to plasma membrane transport vesicle Source: MGI
- intracellular membrane-bounded organelle Source: MGI
- intrinsic component of membrane Source: MGI
- neurofibrillary tangle Source: Alzheimers_University_of_Toronto
- neuron projection Source: MGI
- neuronal cell body Source: Alzheimers_University_of_Toronto
- parallel fiber to Purkinje cell synapse Source: MGI
- postsynapse Source: MGI
- postsynaptic density Source: MGI
- Schaffer collateral - CA1 synapse Source: MGI
- synapse Source: MGI
- synaptic vesicle Source: MGI
- vesicle Source: Alzheimers_University_of_Toronto
Keywords - Cellular componenti
Cell membrane, Coated pit, Cytoplasmic vesicle, Golgi apparatus, Membrane, NucleusPathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000187063 | 2 – 660 | Phosphatidylinositol-binding clathrin assembly proteinAdd BLAST | 659 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserineBy similarity | 1 | |
Modified residuei | 16 | PhosphoserineBy similarity | 1 | |
Modified residuei | 20 | PhosphoserineBy similarity | 1 | |
Cross-linki | 238 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 303 | PhosphoserineBy similarity | 1 | |
Modified residuei | 315 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
jPOSTi | Q7M6Y3 |
MaxQBi | Q7M6Y3 |
PaxDbi | Q7M6Y3 |
PeptideAtlasi | Q7M6Y3 |
PRIDEi | Q7M6Y3 |
ProteomicsDBi | 288151 [Q7M6Y3-1] 288152 [Q7M6Y3-2] 288153 [Q7M6Y3-3] 288154 [Q7M6Y3-4] 288155 [Q7M6Y3-5] 288156 [Q7M6Y3-6] |
PTM databases
iPTMneti | Q7M6Y3 |
PhosphoSitePlusi | Q7M6Y3 |
SwissPalmi | Q7M6Y3 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSMUSG00000039361, Expressed in humerus cartilage element and 293 other tissues |
Genevisiblei | Q7M6Y3, MM |
Interactioni
Subunit structurei
Binds to clathrin; involves primarily the C-terminal sequences, but the full-length protein is required for full binding capacity. Binds phosphatidylinositol 4,5- bisphosphate.
Interacts with PIMREG; this interaction may change the subcellular location into the nucleus.
Interacts with AP2A1 (via its alpha-appendage domain).
Interacts (via N-terminus) with VAMP2; VAMP3; VAMP7 and VAMP8 (Via N-terminus).
Interacts with LC3/MAP1LC3A.
By similarityGO - Molecular functioni
- clathrin binding Source: UniProtKB
- clathrin heavy chain binding Source: MGI
- identical protein binding Source: MGI
- low-density lipoprotein particle receptor binding Source: MGI
- SH3 domain binding Source: MGI
- small GTPase binding Source: MGI
- SNARE binding Source: MGI
- tau protein binding Source: MGI
Protein-protein interaction databases
BioGRIDi | 231417, 9 interactors |
ELMi | Q7M6Y3 |
IntActi | Q7M6Y3, 2 interactors |
STRINGi | 10090.ENSMUSP00000051092 |
Miscellaneous databases
RNActi | Q7M6Y3, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 14 – 145 | ENTHPROSITE-ProRule annotationCuratedAdd BLAST | 132 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 221 – 294 | Interaction with PIMREGBy similarityAdd BLAST | 74 | |
Regioni | 556 – 580 | DisorderedSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0251, Eukaryota |
GeneTreei | ENSGT00950000183068 |
HOGENOMi | CLU_014080_0_0_1 |
InParanoidi | Q7M6Y3 |
OMAi | XPFSATV |
OrthoDBi | 1592722at2759 |
PhylomeDBi | Q7M6Y3 |
TreeFami | TF314861 |
Family and domain databases
Gene3Di | 1.20.58.150, 1 hit 1.25.40.90, 1 hit |
InterProi | View protein in InterPro IPR011417, ANTH_dom IPR014712, ANTH_dom_sf IPR045192, AP180-like IPR013809, ENTH IPR008942, ENTH_VHS IPR030412, PICALM |
PANTHERi | PTHR22951, PTHR22951, 1 hit PTHR22951:SF16, PTHR22951:SF16, 1 hit |
Pfami | View protein in Pfam PF07651, ANTH, 1 hit |
SMARTi | View protein in SMART SM00273, ENTH, 1 hit |
SUPFAMi | SSF48464, SSF48464, 1 hit |
PROSITEi | View protein in PROSITE PS50942, ENTH, 1 hit |
s (6+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 6 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 6 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN
60 70 80 90 100
EMNVNIPQLA DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR
110 120 130 140 150
NTLFNLSNFL DKSGLQGYDM STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR
160 170 180 190 200
GADGVMRTMN TEKLLKTVPI IQNQMDALLD FNVNSNELTN GVINAAFMLL
210 220 230 240 250
FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF LTRMTRISEF
260 270 280 290 300
LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT
310 320 330 340 350
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP
360 370 380 390 400
HTSLTTAASP VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT
410 420 430 440 450
FHPSVHAMSA APQGASTWGD PFSATLDAVE DAIPSLNPFL TKSSGDVHLP
460 470 480 490 500
IASDVSTFTT RTPTHEMFVG FSPSPVAQPH SSAGLNVDFE SVFGNKSTNV
510 520 530 540 550
AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL DSSLANLVGN
560 570 580 590 600
LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ
610 620 630 640 650
YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG
660
PVSGAQIQFM
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A140LHQ8 | A0A140LHQ8_MOUSE | Phosphatidylinositol-binding clathr... | Picalm | 531 | Annotation score: | ||
A0A1L1SUR7 | A0A1L1SUR7_MOUSE | Phosphatidylinositol-binding clathr... | Picalm | 404 | Annotation score: | ||
A0A140LHG9 | A0A140LHG9_MOUSE | Phosphatidylinositol-binding clathr... | Picalm | 85 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 522 | N → S in AAH21491 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 522 | N → S in AAH23843 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 522 | N → S in AAH25566 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 522 | N → S in AAH57683 (PubMed:15489334).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_050684 | 420 – 469 | Missing in isoform 2, isoform 3 and isoform 4. 2 PublicationsAdd BLAST | 50 | |
Alternative sequenceiVSP_050685 | 506 – 510 | Missing in isoform 2, isoform 3 and isoform 5. 2 Publications | 5 | |
Alternative sequenceiVSP_050686 | 594 – 601 | Missing in isoform 2 and isoform 6. 2 Publications | 8 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY206701 mRNA Translation: AAO17153.1 BK001028 mRNA Translation: DAA01470.1 BC011470 mRNA Translation: AAH11470.1 BC021491 mRNA Translation: AAH21491.1 BC023843 mRNA Translation: AAH23843.1 BC025566 mRNA Translation: AAH25566.1 BC027116 mRNA Translation: AAH27116.1 BC057683 mRNA Translation: AAH57683.1 AK085472 mRNA Translation: BAC39454.2 Different initiation. AK162360 mRNA Translation: BAE36872.1 |
CCDSi | CCDS52307.1 [Q7M6Y3-1] CCDS85334.1 [Q7M6Y3-6] CCDS85335.1 [Q7M6Y3-5] CCDS85336.1 [Q7M6Y3-4] CCDS85337.1 [Q7M6Y3-3] CCDS85338.1 [Q7M6Y3-2] |
RefSeqi | NP_001239449.1, NM_001252520.1 [Q7M6Y3-5] NP_001239450.1, NM_001252521.1 [Q7M6Y3-6] NP_001239451.1, NM_001252522.1 [Q7M6Y3-4] NP_001239452.1, NM_001252523.1 [Q7M6Y3-3] NP_001239453.1, NM_001252524.1 [Q7M6Y3-2] NP_666306.2, NM_146194.4 [Q7M6Y3-1] |
Genome annotation databases
Ensembli | ENSMUST00000049537; ENSMUSP00000051092; ENSMUSG00000039361 [Q7M6Y3-5] ENSMUST00000207225; ENSMUSP00000146659; ENSMUSG00000039361 [Q7M6Y3-2] ENSMUST00000207484; ENSMUSP00000146501; ENSMUSG00000039361 [Q7M6Y3-1] ENSMUST00000208730; ENSMUSP00000146541; ENSMUSG00000039361 [Q7M6Y3-3] ENSMUST00000208742; ENSMUSP00000147016; ENSMUSG00000039361 [Q7M6Y3-6] ENSMUST00000209068; ENSMUSP00000146386; ENSMUSG00000039361 [Q7M6Y3-4] |
GeneIDi | 233489 |
KEGGi | mmu:233489 |
UCSCi | uc009igq.2, mouse [Q7M6Y3-1] uc009igr.2, mouse [Q7M6Y3-5] uc009igs.2, mouse [Q7M6Y3-6] uc009igt.2, mouse [Q7M6Y3-4] uc009igu.2, mouse [Q7M6Y3-3] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY206701 mRNA Translation: AAO17153.1 BK001028 mRNA Translation: DAA01470.1 BC011470 mRNA Translation: AAH11470.1 BC021491 mRNA Translation: AAH21491.1 BC023843 mRNA Translation: AAH23843.1 BC025566 mRNA Translation: AAH25566.1 BC027116 mRNA Translation: AAH27116.1 BC057683 mRNA Translation: AAH57683.1 AK085472 mRNA Translation: BAC39454.2 Different initiation. AK162360 mRNA Translation: BAE36872.1 |
CCDSi | CCDS52307.1 [Q7M6Y3-1] CCDS85334.1 [Q7M6Y3-6] CCDS85335.1 [Q7M6Y3-5] CCDS85336.1 [Q7M6Y3-4] CCDS85337.1 [Q7M6Y3-3] CCDS85338.1 [Q7M6Y3-2] |
RefSeqi | NP_001239449.1, NM_001252520.1 [Q7M6Y3-5] NP_001239450.1, NM_001252521.1 [Q7M6Y3-6] NP_001239451.1, NM_001252522.1 [Q7M6Y3-4] NP_001239452.1, NM_001252523.1 [Q7M6Y3-3] NP_001239453.1, NM_001252524.1 [Q7M6Y3-2] NP_666306.2, NM_146194.4 [Q7M6Y3-1] |
3D structure databases
SMRi | Q7M6Y3 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 231417, 9 interactors |
ELMi | Q7M6Y3 |
IntActi | Q7M6Y3, 2 interactors |
STRINGi | 10090.ENSMUSP00000051092 |
PTM databases
iPTMneti | Q7M6Y3 |
PhosphoSitePlusi | Q7M6Y3 |
SwissPalmi | Q7M6Y3 |
Proteomic databases
jPOSTi | Q7M6Y3 |
MaxQBi | Q7M6Y3 |
PaxDbi | Q7M6Y3 |
PeptideAtlasi | Q7M6Y3 |
PRIDEi | Q7M6Y3 |
ProteomicsDBi | 288151 [Q7M6Y3-1] 288152 [Q7M6Y3-2] 288153 [Q7M6Y3-3] 288154 [Q7M6Y3-4] 288155 [Q7M6Y3-5] 288156 [Q7M6Y3-6] |
Protocols and materials databases
Antibodypediai | 17636, 206 antibodies from 34 providers |
DNASUi | 233489 |
Genome annotation databases
Ensembli | ENSMUST00000049537; ENSMUSP00000051092; ENSMUSG00000039361 [Q7M6Y3-5] ENSMUST00000207225; ENSMUSP00000146659; ENSMUSG00000039361 [Q7M6Y3-2] ENSMUST00000207484; ENSMUSP00000146501; ENSMUSG00000039361 [Q7M6Y3-1] ENSMUST00000208730; ENSMUSP00000146541; ENSMUSG00000039361 [Q7M6Y3-3] ENSMUST00000208742; ENSMUSP00000147016; ENSMUSG00000039361 [Q7M6Y3-6] ENSMUST00000209068; ENSMUSP00000146386; ENSMUSG00000039361 [Q7M6Y3-4] |
GeneIDi | 233489 |
KEGGi | mmu:233489 |
UCSCi | uc009igq.2, mouse [Q7M6Y3-1] uc009igr.2, mouse [Q7M6Y3-5] uc009igs.2, mouse [Q7M6Y3-6] uc009igt.2, mouse [Q7M6Y3-4] uc009igu.2, mouse [Q7M6Y3-3] |
Organism-specific databases
CTDi | 8301 |
MGIi | MGI:2385902, Picalm |
VEuPathDBi | HostDB:ENSMUSG00000039361 |
Phylogenomic databases
eggNOGi | KOG0251, Eukaryota |
GeneTreei | ENSGT00950000183068 |
HOGENOMi | CLU_014080_0_0_1 |
InParanoidi | Q7M6Y3 |
OMAi | XPFSATV |
OrthoDBi | 1592722at2759 |
PhylomeDBi | Q7M6Y3 |
TreeFami | TF314861 |
Enzyme and pathway databases
Reactomei | R-MMU-432722, Golgi Associated Vesicle Biogenesis R-MMU-8856825, Cargo recognition for clathrin-mediated endocytosis R-MMU-8856828, Clathrin-mediated endocytosis R-MMU-9696264, RND3 GTPase cycle |
Miscellaneous databases
BioGRID-ORCSi | 233489, 7 hits in 67 CRISPR screens |
ChiTaRSi | Picalm, mouse |
PROi | PR:Q7M6Y3 |
RNActi | Q7M6Y3, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000039361, Expressed in humerus cartilage element and 293 other tissues |
Genevisiblei | Q7M6Y3, MM |
Family and domain databases
Gene3Di | 1.20.58.150, 1 hit 1.25.40.90, 1 hit |
InterProi | View protein in InterPro IPR011417, ANTH_dom IPR014712, ANTH_dom_sf IPR045192, AP180-like IPR013809, ENTH IPR008942, ENTH_VHS IPR030412, PICALM |
PANTHERi | PTHR22951, PTHR22951, 1 hit PTHR22951:SF16, PTHR22951:SF16, 1 hit |
Pfami | View protein in Pfam PF07651, ANTH, 1 hit |
SMARTi | View protein in SMART SM00273, ENTH, 1 hit |
SUPFAMi | SSF48464, SSF48464, 1 hit |
PROSITEi | View protein in PROSITE PS50942, ENTH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PICAL_MOUSE | |
Accessioni | Q7M6Y3Primary (citable) accession number: Q7M6Y3 Secondary accession number(s): Q3TS04 Q921L0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 1, 2004 |
Last sequence update: | December 15, 2003 | |
Last modified: | February 23, 2022 | |
This is version 153 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families