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UniProtKB - Q7LYX6 (MALG_THELN)
Protein
Trehalose/maltose transport system permease protein MalG
Gene
malG
Organism
Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)
Status
Functioni
Part of the ABC transporter complex MalEFGK involved in trehalose/maltose import. Responsible for the translocation of the substrate across the membrane.
2 PublicationsGO - Biological processi
- carbohydrate transport Source: UniProtKB-KW
- transmembrane transport Source: InterPro
Keywordsi
Biological process | Sugar transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Trehalose/maltose transport system permease protein MalG |
Gene namesi | Name:malG ORF Names:OCC_03552 |
Organismi | Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) |
Taxonomic identifieri | 523849 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication; Multi-pass membrane protein PROSITE-ProRule annotation1 Publication
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 32 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 74 – 94 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 106 – 126 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 141 – 161 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 186 – 206 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 242 – 262 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000421287 | 1 – 278 | Trehalose/maltose transport system permease protein MalGAdd BLAST | 278 |
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).
2 PublicationsProtein-protein interaction databases
STRINGi | 523849.OCC_03552 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 70 – 262 | ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST | 193 |
Sequence similaritiesi
Belongs to the binding-protein-dependent transport system permease family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
HOGENOMi | CLU_016047_1_2_2 |
OMAi | DGYSFPK |
OrthoDBi | 57718at2157 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7LYX6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MREEVLKRIL LIIGAILMAI ICLFPFIWMI VVSFAEDPTF LGSPLVEYKS
60 70 80 90 100
TLENYVRVLS DPTLHFPAYL KNSIIIASLV TLTTVSISSL AAYAVSRIEF
110 120 130 140 150
KGRLLIPIFV LGLSMFPQIS LVGYLFKFIE KLGWVNTYQA LYFPYVAWTL
160 170 180 190 200
PLSLWILLSY FSQLPKDLDE AAMIDGASRI KTLTTIILPL SAPALFSTAL
210 220 230 240 250
LVFIAAFNEF MFALLFTTDH RARTVPVGIA LFQGVHGEIP WGSVMAASVI
260 270
STIPLVIMAL LFQKYIVSGL TAGALKGE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF012836 Genomic DNA Translation: AAC38138.1 AF307053 Genomic DNA Translation: AAG45390.1 CP006670 Genomic DNA Translation: EHR78232.1 |
RefSeqi | WP_004068721.1, NC_022084.1 |
Genome annotation databases
EnsemblBacteriai | EHR78232; EHR78232; OCC_03552 |
GeneIDi | 16548947 |
KEGGi | tlt:OCC_03552 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF012836 Genomic DNA Translation: AAC38138.1 AF307053 Genomic DNA Translation: AAG45390.1 CP006670 Genomic DNA Translation: EHR78232.1 |
RefSeqi | WP_004068721.1, NC_022084.1 |
3D structure databases
SMRi | Q7LYX6 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 523849.OCC_03552 |
Genome annotation databases
EnsemblBacteriai | EHR78232; EHR78232; OCC_03552 |
GeneIDi | 16548947 |
KEGGi | tlt:OCC_03552 |
Phylogenomic databases
HOGENOMi | CLU_016047_1_2_2 |
OMAi | DGYSFPK |
OrthoDBi | 57718at2157 |
Family and domain databases
CDDi | cd06261, TM_PBP2, 1 hit |
Gene3Di | 1.10.3720.10, 1 hit |
InterProi | View protein in InterPro IPR000515, MetI-like IPR035906, MetI-like_sf |
Pfami | View protein in Pfam PF00528, BPD_transp_1, 1 hit |
SUPFAMi | SSF161098, SSF161098, 1 hit |
PROSITEi | View protein in PROSITE PS50928, ABC_TM1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MALG_THELN | |
Accessioni | Q7LYX6Primary (citable) accession number: Q7LYX6 Secondary accession number(s): H3ZP65 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 6, 2013 |
Last sequence update: | July 5, 2004 | |
Last modified: | February 23, 2022 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |