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Protein
Submitted name:

Intrinsic factor-vitamin B12 receptor

Gene

CUBN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptorImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Intrinsic factor-vitamin B12 receptorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CUBNImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi29 ↔ 38PROSITE-ProRule annotation
Disulfide bondi72 ↔ 81PROSITE-ProRule annotation
Disulfide bondi270 ↔ 280PROSITE-ProRule annotation
Disulfide bondi291 ↔ 300PROSITE-ProRule annotation
Disulfide bondi329 ↔ 338PROSITE-ProRule annotation
Disulfide bondi1491 ↔ 1518PROSITE-ProRule annotation
Disulfide bondi2207 ↔ 2234PROSITE-ProRule annotation
Disulfide bondi2908 ↔ 2935PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q7LC53

PRoteomics IDEntifications database

More...
PRIDEi
Q7LC53

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q7LC53

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 39EGF-likeInterPro annotationAdd BLAST37
Domaini41 – 82EGF-likeInterPro annotationAdd BLAST42
Domaini134 – 175EGF-likeInterPro annotationAdd BLAST42
Domaini220 – 256EGF-likeInterPro annotationAdd BLAST37
Domaini266 – 301EGF-likeInterPro annotationAdd BLAST36
Domaini303 – 339EGF-likeInterPro annotationAdd BLAST37
Domaini345 – 457CUBInterPro annotationAdd BLAST113
Domaini461 – 573CUBInterPro annotationAdd BLAST113
Domaini579 – 687CUBInterPro annotationAdd BLAST109
Domaini687 – 799CUBInterPro annotationAdd BLAST113
Domaini803 – 913CUBInterPro annotationAdd BLAST111
Domaini919 – 1032CUBInterPro annotationAdd BLAST114
Domaini1036 – 1148CUBInterPro annotationAdd BLAST113
Domaini1149 – 1260CUBInterPro annotationAdd BLAST112
Domaini1262 – 1377CUBInterPro annotationAdd BLAST116
Domaini1381 – 1490CUBInterPro annotationAdd BLAST110
Domaini1491 – 1605CUBInterPro annotationAdd BLAST115
Domaini1609 – 1721CUBInterPro annotationAdd BLAST113
Domaini1723 – 1834CUBInterPro annotationAdd BLAST112
Domaini1849 – 1962CUBInterPro annotationAdd BLAST114
Domaini1963 – 2084CUBInterPro annotationAdd BLAST122
Domaini2088 – 2205CUBInterPro annotationAdd BLAST118
Domaini2207 – 2319CUBInterPro annotationAdd BLAST113
Domaini2323 – 2436CUBInterPro annotationAdd BLAST114
Domaini2441 – 2558CUBInterPro annotationAdd BLAST118
Domaini2560 – 2672CUBInterPro annotationAdd BLAST113
Domaini2676 – 2790CUBInterPro annotationAdd BLAST115
Domaini2791 – 2906CUBInterPro annotationAdd BLAST116
Domaini2908 – 3021CUBInterPro annotationAdd BLAST114
Domaini3028 – 3145CUBInterPro annotationAdd BLAST118
Domaini3149 – 3264CUBInterPro annotationAdd BLAST116
Domaini3266 – 3378CUBInterPro annotationAdd BLAST113
Domaini3382 – 3494CUBInterPro annotationAdd BLAST113

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3714 Eukaryota
ENOG410ZPX7 LUCA

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG080357

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00041 CUB, 27 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.290, 27 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000859 CUB_dom
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR024731 EGF_dom
IPR035914 Sperma_CUB_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00431 CUB, 27 hits
PF00008 EGF, 3 hits
PF12947 EGF_3, 1 hit
PF07645 EGF_CA, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00042 CUB, 27 hits
SM00181 EGF, 8 hits
SM00179 EGF_CA, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49854 SSF49854, 27 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010 ASX_HYDROXYL, 4 hits
PS01180 CUB, 27 hits
PS00022 EGF_1, 4 hits
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 6 hits
PS01187 EGF_CA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q7LC53-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
TVDKKVCSSN PCQNGGNCLN LHDSFFCICP PQWKGPLCSA DVNECEIYSG
60 70 80 90 100
TPLSCQNGGT CVNTMGSYSC HCPPETYGPQ CASKYDDCEG GSVARCVHGI
110 120 130 140 150
CEDLMREQAG EPKYSCVCDA GWMSSPNSPA CTLDRDECSF QPGPCSTLVQ
160 170 180 190 200
CFNTQGSFYC GACPTGWQGN GYICEDINEC EINNGGCSVA PPVECVNTPG
210 220 230 240 250
SSHCQACPPG YQGDGRVCTL TDICSVSNGG CHPDASCSST LGSLPLCTCL
260 270 280 290 300
PGYTGNGYGP NGCVQLSNIC LSHPCLNGQC IDTVSGYFCK CDSGWTGVNC
310 320 330 340 350
TENINECLSN PCLNGGTCVD GVDSFSCECT RLWTGALCQV PQQVCGESLS
360 370 380 390 400
GINGSFSYRS PDVGYVHDVN CFWVIKTEMG KVLRITFTFF RLESMDNCPH
410 420 430 440 450
EFLQVYDGDS SSAFQLGRFC GSSLPHELLS SDNALYFHLY SEHLRNGRGF
460 470 480 490 500
TVRWETQQPE CGGILTGPYG SIKSPGYPGN YPPGRDCVWI VVTSPDLLVT
510 520 530 540 550
FTFGTLSLEH HDDCNKDYLE IRDGPLYQDP LLGKFCTTFS VPPLQTTGPF
560 570 580 590 600
ARIHFHSDSQ ISDQGFHITY LTSPSDLRCG GNYTDPEGEL FLPELSGPFT
610 620 630 640 650
HTRQCVYMMK QPQGEQIQIN FTHVELQCQS DSSQNYIEVR DGETLLGKVC
660 670 680 690 700
GNGTISHIKS ITNSVWIRFK IDASVEKASF RAVYQVACGD ELTGEGVIRS
710 720 730 740 750
PFFPNVYPGE RTCRWTIHQP QSQVILLNFT VFEIGSSAHC ETDYVEIGSS
760 770 780 790 800
SILGSPENKK YCGTDIPSFI TSVYNFLYVT FVKSSSTENH GFMAKFSAED
810 820 830 840 850
LACGEILTES TGTIQSPGHP NVYPHGINCT WHILVQPNHL IHLMFETFHL
860 870 880 890 900
EFHYNCTNDY LEVYDTDSET SLGRYCGKSI PPSLTSSGNS LMLVFVTDSD
910 920 930 940 950
LAYEGFLINY EAISAATACL QDYTDDLGTF TSPNFPNNYP NNWECIYRIT
960 970 980 990 1000
VRTGQLIAVH FTNFSLEEAI GNYYTDFLEI RDGGYEKSPL LGIFYGSNLP
1010 1020 1030 1040 1050
PTIISHSNKL WLKFKSDQID TRSGFSAYWD GSSTGCGGNL TTSSGTFISP
1060 1070 1080 1090 1100
NYPMPYYHSS ECYWWLKSSH GSAFELEFKD FHLEHHPNCT LDYLAVYDGP
1110 1120 1130 1140 1150
SSNSHLLTQL CGDEKPPLIR SSGDSMFIKL RTDEGQQGRG FKAEYRQTCE
1160 1170 1180 1190 1200
NVVIVNQTYG ILESIGYPNP YSENQHCNWT IRATTGNTVN YTFLAFDLEH
1210 1220 1230 1240 1250
HINCSTDYLE LYDGPRQMGR YCGVDLPPPG STTSSKLQVL LLTDGVGRRE
1260 1270 1280 1290 1300
KGFQMQWFVY GCGGELSGAT GSFSSPGFPN RYPPNKECIW YIRTDPGSSI
1310 1320 1330 1340 1350
QLTIHDFDVE YHSRCNFDVL EIYGGPDFHS PRIAQLCTQR SPENPMQVSS
1360 1370 1380 1390 1400
TGNELAIRFK TDLSINGRGF NASWQAVTGG CGGIFQAPSG EIHSPNYPSP
1410 1420 1430 1440 1450
YRSNTDCSWV IRVDRYHRVL LNFTDFDLEP QDSCIMAYDG LSSTMSRLAR
1460 1470 1480 1490 1500
TCGREQLANP IVSSGNSLFL RFQSGPSRQN RGFRAQFRQA CGGHILTSSF
1510 1520 1530 1540 1550
DTVSSPRFPA NYPNNQNCSW IIQAQPPLNH ITLSFTHFEL ERSTTCARDF
1560 1570 1580 1590 1600
VEILDGGHED APLRGRYCGT DMPHPITSFS SALTLRFVSD SSISAGGFHT
1610 1620 1630 1640 1650
TVTASVSACG GTFYMAEGIF NSPGYPDIYP PNVECVWNII SSPGNRLQLS
1660 1670 1680 1690 1700
FISFQLEDSQ DCSRDFVEIR EGNATGHLVG RYCGNSFPLN YSSIVGHTLW
1710 1720 1730 1740 1750
VRFISDGSGS GTGFQATFMK IFGNDNIVGT HGKVASPFWP ENYPHNSNYQ
1760 1770 1780 1790 1800
WTVNVNASHV VHGRILEMDI EEIQNCYYDK LRIYDGPSIH ARLIGAYCGT
1810 1820 1830 1840 1850
QTESFSSTGN SLTFHFYSDS SISGKGFLLE WFAVDAPDGV LPTIAPGACG
1860 1870 1880 1890 1900
GFLRTGDAPV FLFSPGWPDS YSNRVDCTWL IQAPDSTVEL NILSLDIESH
1910 1920 1930 1940 1950
RTCAYDSLVI RDGDNNLAQQ LAVLCGREIP GPIRSTGEYM FIRFTSDSSV
1960 1970 1980 1990 2000
TRAGFNASFH KSCGGYLHAD RGIITSPKYP ETYPSNLNCS WHVLVQSGLT
2010 2020 2030 2040 2050
IAVHFEQPFQ IPNGDSSCNQ GDYLVLRNGP DIYSPPLGPP GGNGHFCGSH
2060 2070 2080 2090 2100
ASSTLFTSDN QMFVQFISDH SNEGQGFKIK YEAKSLACGG NVYIHDADSA
2110 2120 2130 2140 2150
GYVTSPNHPH NYPPHADCIW ILAAPPETRI QLQFEDRFDI EVTPNCTSNY
2160 2170 2180 2190 2200
LELRDGVDSD APILSKFCGT SLPSSQWSSG EVMYLRFRSD NSPTHVGFKA
2210 2220 2230 2240 2250
KYSIAQCGGR VPGQSGVVES IGHPTLPYRD NLFCEWHLQG LSGHYLTISF
2260 2270 2280 2290 2300
EDFNLQNSSG CEKDFVEIWD NHTSGNILGR YCGNTIPDSI DTSSNTAVVR
2310 2320 2330 2340 2350
FVTDGSVTAS GFRLRFESSM EECGGDLQGS IGTFTSPNYP NPNPHGRICE
2360 2370 2380 2390 2400
WRITAPEGRR ITLMFNNLRL ATHPSCNNEH VIVFNGIRSN SPQLEKLCSS
2410 2420 2430 2440 2450
VNVSNEIKSS GNTMKVIFFT DGSRPYGGFT ASYTSSEDAV CGGSLPNTPE
2460 2470 2480 2490 2500
GNFTSPGYDG VRNYSRNLNC EWTLSNPNQG NSSISIHFED FYLESHQDCQ
2510 2520 2530 2540 2550
FDVLEFRVGD ADGPLMWRLC GPSKPTLPLV IPYSQVWIHF VTNERVEHIG
2560 2570 2580 2590 2600
FHAKYSFTDC GGIQIGDSGV ITSPNYPNAY DSLTHCSWLL EAPQGHTITL
2610 2620 2630 2640 2650
TFSDFDIEPH TTCAWDSVTV RNGGSPESPI IGQYCGNSNP RTIQSGSNQL
2660 2670 2680 2690 2700
VVTFNSDHSL QGGGFYATWN TQTLGCGGIF HSDNGTIRSP HWPQNFPENS
2710 2720 2730 2740 2750
RCSWTAITHK SKHLEISFDN NFLIPSGDGQ CQNSFVKVWA GTEEVDKALL
2760 2770 2780 2790 2800
ATGCGNVAPG PVITPSNTFT AVFQSQEAPA QGFSASFVSR CGSNFTGPSG
2810 2820 2830 2840 2850
YIISPNYPKQ YDNNMNCTYV IEANPLSVVL LTFVSFHLEA RSAVTGSCVN
2860 2870 2880 2890 2900
DGVHIIRGYS VMSTPFATVC GDEMPAPLTI AGPVLLNFYS NEQITDFGFK
2910 2920 2930 2940 2950
FSYRIISCGG VFNFSSGIIT SPAYSYADYP NDMHCLYTIT VSDDKVIELK
2960 2970 2980 2990 3000
FSDFDVVPST SCSHDYLAIY DGANTSDPLL GKFCGSKRPP NVKSSNNSML
3010 3020 3030 3040 3050
LVFKTDSFQT AKGWKMSFRQ TLGPQQGCGG YLTGSNNTFA SPDSDSNGMY
3060 3070 3080 3090 3100
DKNLNCVWII IAPVNKVIHL TFNTFALEAA STRQRCLYDY VKLYDGDSEN
3110 3120 3130 3140 3150
ANLAGTFCGS TVPAPFISSG NFLTVQFISD LTLEREGFNA TYTIMDMPCG
3160 3170 3180 3190 3200
GTYNATWTPQ NISSPNSSDP DVPFSICTWV IDSPPHQQVK ITVWALQLTS
3210 3220 3230 3240 3250
QDCTQNYLQL QDSPQGHGNS RFQFCGRNAS AVPVFYSSMS TAMVIFKSGV
3260 3270 3280 3290 3300
VNRNSRMSFT YQIADCNRDY HKAFGNLRSP GWPDNYDNDK DCTVTLTAPQ
3310 3320 3330 3340 3350
NHTISLFFHS LGIENSVECR NDFLEVRNGS NSNSPLLGKY CGTLLPNPVF
3360 3370 3380 3390 3400
SQNNELYLRF KSDSVTSDRG YEIIWTSSPS GCGGTLYGDR GSFTSPGYPG
3410 3420 3430 3440 3450
TYPNNTYCEW VLVAPAGRLV TINFYFISID DPGDCVQNYL TLYDGPNASS
3460 3470 3480 3490
PSSGPYCGGD TSIAPFVASS NQVFIKFHAD YARRPSAFRL TWDS
Length:3,494
Mass (Da):384,285
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i04A811043985DB39
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AH010855
, AF243083, AF243084, AF243085, AF243086, AF243087, AF243088, AF243089, AF243090, AF243091, AF243092, AF243093, AF243094, AF243095, AF243096, AF243097, AF243098, AF243099, AF243100, AF243101, AF243102, AF243103, AF243104, AF243105, AF243106, AF243107, AF243108, AF243109, AF243110, AF243111, AF243112, AF243113, AF243114, AF243115, AF243116, AF243118, AF243119, AF243120, AF243121, AF243122, AF243123, AF243124, AF243125, AF243126, AF243127, AF243128 Genomic DNA Translation: AAK61830.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AH010855
, AF243083, AF243084, AF243085, AF243086, AF243087, AF243088, AF243089, AF243090, AF243091, AF243092, AF243093, AF243094, AF243095, AF243096, AF243097, AF243098, AF243099, AF243100, AF243101, AF243102, AF243103, AF243104, AF243105, AF243106, AF243107, AF243108, AF243109, AF243110, AF243111, AF243112, AF243113, AF243114, AF243115, AF243116, AF243118, AF243119, AF243120, AF243121, AF243122, AF243123, AF243124, AF243125, AF243126, AF243127, AF243128 Genomic DNA Translation: AAK61830.1

3D structure databases

ProteinModelPortaliQ7LC53
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ7LC53
PRIDEiQ7LC53

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3714 Eukaryota
ENOG410ZPX7 LUCA
HOVERGENiHBG080357

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CUBN human

Family and domain databases

CDDicd00041 CUB, 27 hits
Gene3Di2.60.120.290, 27 hits
InterProiView protein in InterPro
IPR000859 CUB_dom
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR024731 EGF_dom
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00431 CUB, 27 hits
PF00008 EGF, 3 hits
PF12947 EGF_3, 1 hit
PF07645 EGF_CA, 3 hits
SMARTiView protein in SMART
SM00042 CUB, 27 hits
SM00181 EGF, 8 hits
SM00179 EGF_CA, 7 hits
SUPFAMiSSF49854 SSF49854, 27 hits
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 4 hits
PS01180 CUB, 27 hits
PS00022 EGF_1, 4 hits
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 6 hits
PS01187 EGF_CA, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ7LC53_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7LC53
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 18, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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