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Protein

Protein ARMCX6

Gene

ARMCX6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May regulate the dynamics and distribution of mitochondria in neural cells.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ARMCX6
Gene namesi
Name:ARMCX6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000198960.10
HGNCiHGNC:26094 ARMCX6
neXtProtiNX_Q7L4S7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 6Mitochondrial intermembraneBy similarity6
Transmembranei7 – 27Helical; Signal-anchorSequence analysisAdd BLAST21
Topological domaini28 – 300CytoplasmicBy similarityAdd BLAST273

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198960
PharmGKBiPA134869551

Polymorphism and mutation databases

BioMutaiARMCX6
DMDMi74749890

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001913741 – 300Protein ARMCX6Add BLAST300

Proteomic databases

PaxDbiQ7L4S7
PeptideAtlasiQ7L4S7
PRIDEiQ7L4S7
ProteomicsDBi68781

PTM databases

iPTMnetiQ7L4S7
PhosphoSitePlusiQ7L4S7

Expressioni

Gene expression databases

BgeeiENSG00000198960
CleanExiHS_ARMCX6
GenevisibleiQ7L4S7 HS

Organism-specific databases

HPAiHPA043030
HPA048125

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000354708

Structurei

3D structure databases

ProteinModelPortaliQ7L4S7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 6Mitochondrion outer membrane (MOM)-targeting sequenceCurated6
Regioni26 – 36Mitochondrion outer membrane (MOM)-targeting sequenceCuratedAdd BLAST11

Sequence similaritiesi

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410II02 Eukaryota
ENOG411142D LUCA
GeneTreeiENSGT00550000074488
HOGENOMiHOG000231611
HOVERGENiHBG097741
InParanoidiQ7L4S7
OMAiKANRAHP
OrthoDBiEOG091G0PCU
PhylomeDBiQ7L4S7
TreeFamiTF335652

Family and domain databases

InterProiView protein in InterPro
IPR006911 ARM-rpt_dom
PfamiView protein in Pfam
PF04826 Arm_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7L4S7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRAREVGWM AAGLMIGAGA CYCVYKLTIG RDDSEKLEEE GEEEWDDDQE
60 70 80 90 100
LDEEEPDIWF DFETMARPWT EDGDWTEPGA PGGTEDRPSG GGKANRAHPI
110 120 130 140 150
KQRPFPYEHK NTWSAQNCKN GSCVLDLSKC LFIQGKLLFA EPKDAGFPFS
160 170 180 190 200
QDINSHLASL SMARNTSPTP DPTVREALCA PDNLNASIES QGQIKMYINE
210 220 230 240 250
VCRETVSRCC NSFLQQAGLN LLISMTVINN MLAKSASDLK FPLISEGSGC
260 270 280 290 300
AKVQVLKPLM GLSEKPVLAG ELVGAQMLFS FMSLFIRNGN REILLETPAP
Length:300
Mass (Da):33,019
Last modified:July 5, 2004 - v1
Checksum:i44393DA4160D88A1
GO

Sequence cautioni

The sequence BAA91387 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121883 Genomic DNA Translation: CAI42938.1
BC007677 mRNA Translation: AAH07677.2
AK000818 mRNA Translation: BAA91387.1 Different initiation.
CCDSiCCDS14488.1
RefSeqiNP_001009584.1, NM_001009584.1
NP_001171697.1, NM_001184768.1
NP_061880.2, NM_019007.3
UniGeneiHs.83530

Genome annotation databases

EnsembliENST00000361910; ENSP00000354708; ENSG00000198960
ENST00000538627; ENSP00000440648; ENSG00000198960
ENST00000539247; ENSP00000444537; ENSG00000198960
GeneIDi54470
KEGGihsa:54470
UCSCiuc004ehx.4 human

Similar proteinsi

Entry informationi

Entry nameiARMX6_HUMAN
AccessioniPrimary (citable) accession number: Q7L4S7
Secondary accession number(s): Q9NWJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 5, 2004
Last modified: June 20, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

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