UniProtKB - Q7KT11 (Q7KT11_DROME)
Protein
Submitted name:
Uncharacterized protein, isoform B
Gene
Dmel\CG9331
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- glyoxylate reductase (NADP) activity Source: GO_Central
- hydroxypyruvate reductase activity Source: GO_Central
- NAD binding Source: InterPro
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: GO_Central
- protein homodimerization activity Source: GO_Central
Keywordsi
Molecular function | OxidoreductaseUniRule annotationImported |
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized protein, isoform BImportedSubmitted name: Uncharacterized protein, isoform DImportedSubmitted name: Uncharacterized protein, isoform FImportedSubmitted name: Uncharacterized protein, isoform GImported (EC:1.1.1.79Imported, EC:1.1.1.81Imported)Submitted name: Uncharacterized protein, isoform JImportedSubmitted name: Uncharacterized protein, isoform KImported |
Gene namesi | Name:Dmel\CG9331Imported ORF Names:CG9331Imported, Dmel_CG9331Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0032889 CG9331 |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Extracellular region or secreted
- extracellular region Source: FlyBase
Expressioni
Gene expression databases
Bgeei | FBgn0032889 Expressed in 39 organ(s), highest expression level in arthropod fat body |
ExpressionAtlasi | Q7KT11 baseline and differential |
Interactioni
GO - Molecular functioni
- protein homodimerization activity Source: GO_Central
Protein-protein interaction databases
IntActi | Q7KT11, 1 interactor |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 9 – 323 | 2-Hacid_dhInterPro annotationAdd BLAST | 315 | |
Domaini | 114 – 294 | 2-Hacid_dh_CInterPro annotationAdd BLAST | 181 |
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0069 Eukaryota COG1052 LUCA |
GeneTreei | ENSGT00940000170865 |
OMAi | VISCHSA |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q7KT11-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAGKAFKVL VTHPEVPQEG IDLLKENCEI VQVQSVPINR AELLEKIRGV
60 70 80 90 100
DGVLWGGHEP LNAEALDAAG PQLKSISTMS AGIDYVDVPE VKRRKIPLGH
110 120 130 140 150
TPTVLNTAVA DLAVGLLIAA SRRFHEGRKT IDNDKWENYH LNWLLGQDIR
160 170 180 190 200
DSTVGFYGFG GIGQAIAKRL SGFDIDKVLY TTRRRVHKEI EEEFNAKKVD
210 220 230 240 250
FDTLLAESDF VVIASPLTKD TQGVFNATAF NKMKQTAVLV NIARGKIVNQ
260 270 280 290 300
DDLYEALKAN RIFSAGLDVT DPEPLSPKDK LLTLDNVVVL PHIGSATKRT
310 320
RADMSTIAAH NVLRGLAGEP MLSPAY
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9VIJ0 | Q9VIJ0_DROME | Uncharacterized protein, isoform A | Dmel\CG9331 CG9331, Dmel_CG9331 | 364 | Annotation score: | ||
Q8SZU0 | Q8SZU0_DROME | GH13879p | Dmel\CG9331 CG9331, Dmel_CG9331 | 364 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014134 Genomic DNA Translation: AAN11092.1 AE014134 Genomic DNA Translation: AAO41215.1 AE014134 Genomic DNA Translation: AAS64729.2 AE014134 Genomic DNA Translation: ADV37106.1 AE014134 Genomic DNA Translation: ADV37107.1 AE014134 Genomic DNA Translation: AHN54622.1 |
RefSeqi | NP_001188857.1, NM_001201928.2 NP_001188858.1, NM_001201929.2 NP_001286108.1, NM_001299179.1 NP_610062.2, NM_136218.4 NP_788081.1, NM_176067.3 NP_995737.2, NM_206015.3 |
UniGenei | Dm.7737 |
Genome annotation databases
EnsemblMetazoai | FBtr0081417; FBpp0080946; FBgn0032889 FBtr0081419; FBpp0080948; FBgn0032889 FBtr0302942; FBpp0292068; FBgn0032889 FBtr0302943; FBpp0292069; FBgn0032889 FBtr0339559; FBpp0308639; FBgn0032889 FBtr0339560; FBpp0308640; FBgn0032889 |
GeneIDi | 35347 |
KEGGi | dme:Dmel_CG9331 |
UCSCi | CG9331-RB d. melanogaster CG9331-RE d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014134 Genomic DNA Translation: AAN11092.1 AE014134 Genomic DNA Translation: AAO41215.1 AE014134 Genomic DNA Translation: AAS64729.2 AE014134 Genomic DNA Translation: ADV37106.1 AE014134 Genomic DNA Translation: ADV37107.1 AE014134 Genomic DNA Translation: AHN54622.1 |
RefSeqi | NP_001188857.1, NM_001201928.2 NP_001188858.1, NM_001201929.2 NP_001286108.1, NM_001299179.1 NP_610062.2, NM_136218.4 NP_788081.1, NM_176067.3 NP_995737.2, NM_206015.3 |
UniGenei | Dm.7737 |
3D structure databases
SMRi | Q7KT11 |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
IntActi | Q7KT11, 1 interactor |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
EnsemblMetazoai | FBtr0081417; FBpp0080946; FBgn0032889 FBtr0081419; FBpp0080948; FBgn0032889 FBtr0302942; FBpp0292068; FBgn0032889 FBtr0302943; FBpp0292069; FBgn0032889 FBtr0339559; FBpp0308639; FBgn0032889 FBtr0339560; FBpp0308640; FBgn0032889 |
GeneIDi | 35347 |
KEGGi | dme:Dmel_CG9331 |
UCSCi | CG9331-RB d. melanogaster CG9331-RE d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0032889 CG9331 |
Phylogenomic databases
eggNOGi | KOG0069 Eukaryota COG1052 LUCA |
GeneTreei | ENSGT00940000170865 |
OMAi | VISCHSA |
Miscellaneous databases
GenomeRNAii | 35347 |
Gene expression databases
Bgeei | FBgn0032889 Expressed in 39 organ(s), highest expression level in arthropod fat body |
ExpressionAtlasi | Q7KT11 baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | Q7KT11_DROME | |
Accessioni | Q7KT11Primary (citable) accession number: Q7KT11 Secondary accession number(s): Q7KT12 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | February 13, 2019 | |
This is version 143 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |