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Entry version 156 (07 Oct 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Transcriptional adapter 2A

Gene

Ada2a

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

GCN5-independent Rpb4 complexes are highly enriched in decondensed chromosome puffs so may play a role in RNA polymerase II-dependent transcription.1 Publication

Miscellaneous

This protein is produced by a bicistronic gene which also produces the Rpb4 protein by alternative splicing.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri90 – 136ZZ-typeSequence analysisAdd BLAST47

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-5689880, Ub-specific processing proteases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcriptional adapter 2A
Alternative name(s):
dADA2a
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ada2a1 PublicationImported
Synonyms:Rpb4Imported
ORF Names:CG43663Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0263738, Ada2a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002837331 – 562Transcriptional adapter 2AAdd BLAST562

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7KSD8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed both maternally and zygotically throughout development with lowest expression levels in L2 and L3 larvae, and highest expression levels during pupal development (PubMed:12482983, PubMed:12697829). Highly expressed in all developmental stages, though its abundance decreases in L2 larvae then returns to high levels in pupae (PubMed:19921261).3 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Under heat shock conditions, strongly down-regulated in L2 stage larvae with levels remaining low during the L3 and pupal stages. In second instar larvae, down-regulated 1 hr after starvation and then appears to return to normal expression levels 4 hr after nutritional starvation.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0263738, Expressed in embryo and 30 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7KSD8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7KSD8, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with Pcaf/GCN5 as part of a GCN5-containing ADA (GNAT) multiprotein complex (PubMed:12482983, PubMed:12697829).

Component of the Ada2a-containing (ATAC) complex composed of at least Ada2a, Atac1, Hcf, Ada3, Gcn5, Mocs2B, Charac-14, Atac3, Atac2, NC2beta and wds (PubMed:18327268).

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
77382, 19 interactors

Protein interaction database and analysis system

More...
IntActi
Q7KSD8, 17 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0302532

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7KSD8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini154 – 198SANTSequence analysisAdd BLAST45
Domaini471 – 562SWIRMPROSITE-ProRule annotationAdd BLAST92

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri90 – 136ZZ-typeSequence analysisAdd BLAST47

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0457, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156751

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_018273_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7KSD8

KEGG Orthology (KO)

More...
KOi
K03012

Identification of Orthologs from Complete Genome Data

More...
OMAi
CHEYDLC

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7KSD8

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00167, SANT, 1 hit
cd02335, ZZ_ADA2, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041983, ADA2-like_ZZ
IPR016827, Ada2/TADA2
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR007526, SWIRM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04433, SWIRM, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF025024, Transcriptional_adaptor_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50934, SWIRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform B1 Publication (identifier: Q7KSD8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSFMNPVDMV DEDAADLQFP KVALLHIFTT LNCLFAVEPL GPQVKRFIHA
60 70 80 90 100
HQNEHTRNSM VLYNPHTLHR YLEEMEEKTR DQNSSVPSAT KDANRCATCR
110 120 130 140 150
CSLTEPYIKC SECLDTLLCL QCFSRGKEAF SHRNNHAYII VRDNIQVFAD
160 170 180 190 200
EPHWTARDER ILLKTLRTHG YGNWEAVSQA LDQRHEPAEV RRHYHDCYFG
210 220 230 240 250
GIFERLLNLK HARDSYVPER MPYVFKMRSL DPPRHDDIAS MQFRLSAGYR
260 270 280 290 300
CARGDFDTPY DTSAESLLSI MVDHRGRDDD NEASESEFER EVTEELQLGL
310 320 330 340 350
VRAYNNRLRE RQRRYKIMRQ HGLIMPNRTV SWISKYVHAF GSDASCMRFL
360 370 380 390 400
GFMQICPDPI KFDMLLESLR YYRELHSQLH KLYDLREHGV RTLSGAKLYA
410 420 430 440 450
RLSKERQQAQ RDYSRLKQTD AFDWQQLVQH YESNRSGDPG PLAINSKLYV
460 470 480 490 500
MNTRRKASPI EIGGGKHFTH CLTPTEYNFS LIPDLPGYSK LDDGERKLCS
510 520 530 540 550
VARLVPQSYL DYKNQLVTEQ AKLGYLRLAD ARRLIKIDVN KTRQIYDFLL
560
EHGHISRPPS YG
Length:562
Mass (Da):65,625
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0AE29DCC8AE4251C
GO
Isoform A1 Publication (identifier: Q7KSD8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     23-37: Missing.

Show »
Length:547
Mass (Da):63,967
Checksum:i5C7AAC1536585346
GO
Isoform C1 Publication (identifier: Q7KSD8-3) [UniParc]FASTAAdd to basket
Also known as: ADA2A-SV21 Publication

The sequence of this isoform differs from the canonical sequence as follows:
     23-37: Missing.
     464-483: Missing.

Show »
Length:527
Mass (Da):61,723
Checksum:iB1BCC6E0B66C51C7
GO
Isoform E1 Publication (identifier: Q7KSD8-4) [UniParc]FASTAAdd to basket
Also known as: ADA2A-SV11 Publication

The sequence of this isoform differs from the canonical sequence as follows:
     464-483: Missing.

Show »
Length:542
Mass (Da):63,381
Checksum:iCA76D6E8E3D471EC
GO
Isoform D1 Publication (identifier: Q9VEA5-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry Q9VEA5.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:139
Mass (Da):16,212
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E1JIP2E1JIP2_DROME
Transcriptional adapter
Ada2a ADA2a, Ada2A, ada2a, CG31318, CG33520
527Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti229S → T in AAN88029 (PubMed:12482983).Curated1
Sequence conflicti229S → T in AAN88030 (PubMed:12482983).Curated1
Sequence conflicti284S → P in AAY51560 (Ref. 4) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05236823 – 37Missing in isoform A and isoform C. 3 PublicationsAdd BLAST15
Alternative sequenceiVSP_052369464 – 483Missing in isoform C and isoform E. 2 PublicationsAdd BLAST20

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF544017 mRNA Translation: AAN88029.1
AF544018 mRNA Translation: AAN88030.1
AE014297 Genomic DNA Translation: AAN13767.1
AE014297 Genomic DNA Translation: AAS65168.1
AE014297 Genomic DNA Translation: AAX52962.1
AE014297 Genomic DNA Translation: AAX52963.1
BT022166 mRNA Translation: AAY51560.1
BT025205 mRNA Translation: ABF17896.1
AY142216 mRNA Translation: AAN52144.1

NCBI Reference Sequences

More...
RefSeqi
NP_001014634.1, NM_001014634.3 [Q7KSD8-4]
NP_001014635.1, NM_001014635.3 [Q7KSD8-2]
NP_001014636.1, NM_001014636.3 [Q7KSD8-1]
NP_001014637.1, NM_001014637.3 [Q7KSD8-3]
NP_001163645.1, NM_001170174.2 [Q7KSD8-3]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0310380; FBpp0302531; FBgn0263738 [Q7KSD8-2]
FBtr0310381; FBpp0302532; FBgn0263738 [Q7KSD8-1]
FBtr0310382; FBpp0302533; FBgn0263738 [Q7KSD8-3]
FBtr0310383; FBpp0302534; FBgn0263738 [Q7KSD8-4]
FBtr0310384; FBpp0302535; FBgn0263738 [Q7KSD8-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
326128

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG43663

UCSC genome browser

More...
UCSCi
CG33520-RA, d. melanogaster [Q7KSD8-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF544017 mRNA Translation: AAN88029.1
AF544018 mRNA Translation: AAN88030.1
AE014297 Genomic DNA Translation: AAN13767.1
AE014297 Genomic DNA Translation: AAS65168.1
AE014297 Genomic DNA Translation: AAX52962.1
AE014297 Genomic DNA Translation: AAX52963.1
BT022166 mRNA Translation: AAY51560.1
BT025205 mRNA Translation: ABF17896.1
AY142216 mRNA Translation: AAN52144.1
RefSeqiNP_001014634.1, NM_001014634.3 [Q7KSD8-4]
NP_001014635.1, NM_001014635.3 [Q7KSD8-2]
NP_001014636.1, NM_001014636.3 [Q7KSD8-1]
NP_001014637.1, NM_001014637.3 [Q7KSD8-3]
NP_001163645.1, NM_001170174.2 [Q7KSD8-3]

3D structure databases

SMRiQ7KSD8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi77382, 19 interactors
IntActiQ7KSD8, 17 interactors
STRINGi7227.FBpp0302532

Proteomic databases

PaxDbiQ7KSD8

Genome annotation databases

EnsemblMetazoaiFBtr0310380; FBpp0302531; FBgn0263738 [Q7KSD8-2]
FBtr0310381; FBpp0302532; FBgn0263738 [Q7KSD8-1]
FBtr0310382; FBpp0302533; FBgn0263738 [Q7KSD8-3]
FBtr0310383; FBpp0302534; FBgn0263738 [Q7KSD8-4]
FBtr0310384; FBpp0302535; FBgn0263738 [Q7KSD8-3]
GeneIDi326128
KEGGidme:Dmel_CG43663
UCSCiCG33520-RA, d. melanogaster [Q7KSD8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
373884
FlyBaseiFBgn0263738, Ada2a

Phylogenomic databases

eggNOGiKOG0457, Eukaryota
GeneTreeiENSGT00940000156751
HOGENOMiCLU_018273_3_0_1
InParanoidiQ7KSD8
KOiK03012
OMAiCHEYDLC
PhylomeDBiQ7KSD8

Enzyme and pathway databases

ReactomeiR-DME-5689880, Ub-specific processing proteases

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
326128, 0 hits in 5 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
326128

Gene expression databases

BgeeiFBgn0263738, Expressed in embryo and 30 other tissues
ExpressionAtlasiQ7KSD8, baseline and differential
GenevisibleiQ7KSD8, DM

Family and domain databases

CDDicd00167, SANT, 1 hit
cd02335, ZZ_ADA2, 1 hit
InterProiView protein in InterPro
IPR041983, ADA2-like_ZZ
IPR016827, Ada2/TADA2
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR007526, SWIRM
PfamiView protein in Pfam
PF04433, SWIRM, 1 hit
PIRSFiPIRSF025024, Transcriptional_adaptor_2, 1 hit
SUPFAMiSSF46689, SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS50934, SWIRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTAD2A_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7KSD8
Secondary accession number(s): Q4V6Z0
, Q59DW3, Q59DW4, Q8I8U8, Q8I9F2, Q8I9F3, Q8IN85
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: July 5, 2004
Last modified: October 7, 2020
This is version 156 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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