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Entry version 128 (10 Feb 2021)
Sequence version 1 (05 Jul 2004)
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Protein
Submitted name:

Moira

Gene

mor

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • histone binding Source: GO_Central
  • identical protein binding Source: IntAct

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
MoiraImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:morImported
ORF Names:CG18740Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0002783, mor

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q7KPY3

PRoteomics IDEntifications database

More...
PRIDEi
Q7KPY3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0002783, Expressed in embryo and 64 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q7KPY3, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q7KPY3, 5 interactors

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini430 – 527SWIRMInterPro annotationAdd BLAST98
Domaini630 – 681SANTInterPro annotationAdd BLAST52

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni265 – 424DisorderedSequence analysisAdd BLAST160
Regioni773 – 919DisorderedSequence analysisAdd BLAST147
Regioni1040 – 1189DisorderedSequence analysisAdd BLAST150

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili964 – 994Sequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi284 – 302PolarSequence analysisAdd BLAST19
Compositional biasi342 – 356PolarSequence analysisAdd BLAST15
Compositional biasi384 – 413PolarSequence analysisAdd BLAST30
Compositional biasi799 – 821PolyampholyteSequence analysisAdd BLAST23
Compositional biasi822 – 876PolarSequence analysisAdd BLAST55
Compositional biasi886 – 902PolyampholyteSequence analysisAdd BLAST17
Compositional biasi1040 – 1062PolarSequence analysisAdd BLAST23
Compositional biasi1124 – 1161PolarSequence analysisAdd BLAST38

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036420, BRCT_dom_sf
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR038044, SMARCC2
IPR032451, SMARCC_C
IPR032450, SMARCC_N
IPR007526, SWIRM
IPR032448, SWIRM-assoc
IPR036388, WH-like_DNA-bd_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12802:SF105, PTHR12802:SF105, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00249, Myb_DNA-binding, 1 hit
PF04433, SWIRM, 1 hit
PF16495, SWIRM-assoc_1, 1 hit
PF16496, SWIRM-assoc_2, 1 hit
PF16498, SWIRM-assoc_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00717, SANT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 2 hits
SSF52113, SSF52113, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51293, SANT, 1 hit
PS50934, SWIRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7KPY3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALSGGEKKT IYSQPYLLQY LAHSSEPITK ESLAQLFIHF LQYVEAKLGK
60 70 80 90 100
NSADPPATRI PMRCFLDFKS GGGLCIIFST MFRFRAEQRG KKFDFSIGKN
110 120 130 140 150
PTRKDPNIQL LIEIEQALVE ADLYRIPYIY IRPEIEKGFE GKLREILDNR
160 170 180 190 200
RVEIVSDEED ATHIVYPVVD PHPDEYARPI FKRGGHVMLH WYYFPESYDS
210 220 230 240 250
WAVNNFDLPD HIPENPESPA ERWRVSASWI VDLEQYNEWM AEEDYEVDEQ
260 270 280 290 300
GKKKTHKQRM SIDDIMSFGD EKKKPAASSG GGKQKRRRSP SPASSASTSK
310 320 330 340 350
PGKRKRSPAV VHKKSRNDDD DEDLTRDLDD PPAEPNVQEV HKANAALQST
360 370 380 390 400
ASPAPGGKSR GDNDMMPIKG GTMTDLDDEM TGGSAAQAMS TGDGENSQTG
410 420 430 440 450
KTSDNSNTQE FSSSAKEDME DNVTEQTHHI IVPSYSAWFD YNSIHVIEKR
460 470 480 490 500
AMPEFFNSKN KSKTPEIYMA YRNFMIDTYR LNPTEYLTTT ACRRNLAGDV
510 520 530 540 550
CAIMRVHAFL EQWGLINYQI DADVRPTPMG PPPTSHFHIL SDTPSGLQSI
560 570 580 590 600
NPQKTQQPSA AKTLLDLDKK PLGKDGGLEL GDKSGLTGIK TEALENGAAG
610 620 630 640 650
GLSSGVSQFG LKLDQYAKKP AAMRNRTAAS MAREWTDQET LLLLEGLEMH
660 670 680 690 700
KDDWNKVCEH VGSRTQDECI LHFLRLPIED PYLEDDGGFL GPLACQPIPF
710 720 730 740 750
SKSGNPIMST VAFLASVVDP RVAAAAAKAA MEEFAAIKDE VPATIMDNHL
760 770 780 790 800
KNVEKASAGG KFNPNFGLAN SGIAGTGNDK DDEEGKEGGA SASAGGSDEE
810 820 830 840 850
MKDLSKKDDD AKSKDNTKSD KTNTNTDSSS TSSSATGNTN NTDKKPKESS
860 870 880 890 900
GSSPSGDKSA IKSDKSNKSS PTETAAAASG GEVDIKTEDS SGDGETKDGT
910 920 930 940 950
EAKEGTGTGT GPLAVPKEGT FSENNMQTAA AAALASAAVK AKHLAALEER
960 970 980 990 1000
KIKSLVALLV ETQMKKLEIK LRHFEELEAT MEREREGLEY QRQQLITERQ
1010 1020 1030 1040 1050
QFHLEQLKAA EFRARQQAHH RLQQELQGQA AAGSMILPQQ QQLPQAQQPQ
1060 1070 1080 1090 1100
QQQQTLPPHP HLAQQQQLPP HPHQLPPQSQ PLAGPTAQHQ PLPPHVVSSP
1110 1120 1130 1140 1150
NGAPFAAPPI SLTGGLPPGA PTAIVTNPSD QTGPVAAGAA QSQAPTPMDT
1160 1170 1180
TPPSSGPVSD ANAPPGSAMP PGGIPPANTA PIAGVAPSS
Length:1,189
Mass (Da):129,025
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E59C06E00B7C50A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF033823 mRNA Translation: AAD12718.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033823 mRNA Translation: AAD12718.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ7KPY3, 5 interactors

Proteomic databases

PeptideAtlasiQ7KPY3
PRIDEiQ7KPY3

Organism-specific databases

FlyBaseiFBgn0002783, mor

Gene expression databases

BgeeiFBgn0002783, Expressed in embryo and 64 other tissues
ExpressionAtlasiQ7KPY3, baseline and differential

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR036420, BRCT_dom_sf
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR038044, SMARCC2
IPR032451, SMARCC_C
IPR032450, SMARCC_N
IPR007526, SWIRM
IPR032448, SWIRM-assoc
IPR036388, WH-like_DNA-bd_sf
PANTHERiPTHR12802:SF105, PTHR12802:SF105, 1 hit
PfamiView protein in Pfam
PF00249, Myb_DNA-binding, 1 hit
PF04433, SWIRM, 1 hit
PF16495, SWIRM-assoc_1, 1 hit
PF16496, SWIRM-assoc_2, 1 hit
PF16498, SWIRM-assoc_3, 1 hit
SMARTiView protein in SMART
SM00717, SANT, 1 hit
SUPFAMiSSF46689, SSF46689, 2 hits
SSF52113, SSF52113, 1 hit
PROSITEiView protein in PROSITE
PS51293, SANT, 1 hit
PS50934, SWIRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ7KPY3_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7KPY3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 10, 2021
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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