UniProtKB - Q7K4Y8 (Q7K4Y8_DROME)
Protein
Submitted name:
GH22690p
Gene
Dmel\CG1909
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- acetylcholine receptor binding Source: FlyBase
- protein-membrane adaptor activity Source: InterPro
- zinc ion binding Source: FlyBase
GO - Biological processi
- synaptic transmission, cholinergic Source: FlyBase
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: GH22690pImportedSubmitted name: Uncharacterized protein, isoform AImportedSubmitted name: Uncharacterized protein, isoform BImported |
Gene namesi | Name:Dmel\CG1909Imported ORF Names:CG1909Imported, Dmel_CG1909Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0039911, CG1909 |
Subcellular locationi
Other locations
- synapse Source: GOC
Interactioni
GO - Molecular functioni
- acetylcholine receptor binding Source: FlyBase
Protein-protein interaction databases
IntActi | Q7K4Y8, 4 interactors |
STRINGi | 7227.FBpp0088148 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 94 – 366 | TPR_REGIONInterPro annotationAdd BLAST | 273 | |
Domaini | 455 – 502 | RING-typeInterPro annotationAdd BLAST | 48 |
Keywords - Domaini
TPR repeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG1941, Eukaryota |
GeneTreei | ENSGT00390000016785 |
HOGENOMi | CLU_030911_1_0_1 |
OMAi | QGAYKIA |
OrthoDBi | 1245397at2759 |
Family and domain databases
Gene3Di | 1.25.40.10, 2 hits 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR019568, Rapsyn_myristoylation/link_N IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF10579, Rapsyn_N, 1 hit |
SUPFAMi | SSF48452, SSF48452, 2 hits |
PROSITEi | View protein in PROSITE PS50293, TPR_REGION, 1 hit PS50089, ZF_RING_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7K4Y8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSWESINSKD LLSIPPSQNL SATRLLTSPD GSRYLLENSS DLCHLDESFS
60 70 80 90 100
RLAGYGSSPD VGSRSVWASQ ALLRSGSVIS CFLSCQQSLR QYIAKRKIER
110 120 130 140 150
GRRLYEQNNQ TEAVRTWRSA LKGTCQREDC FQLLGYLYQA HMDWGKFREA
160 170 180 190 200
IEFSHQQLGI SEELDSPNMR AETYLNLSRA HASLGGLERS LSYARHSLYN
210 220 230 240 250
ECGTKCRSGL VHLTVARVYL EMGGFSRALE GLQGAYKIAT AIGDPSLELQ
260 270 280 290 300
VYVALSELFG RLQDNDKSAT YASKAYDLSR SLQLGDLNSC HHRAALLRMA
310 320 330 340 350
VSLRKQGELG DAQDYCKEAT KLSLISGDQA TYTRSIRVMG DIYRNKMDMD
360 370 380 390 400
RAFRQYEQAM GTSASLGDRM AQMEAMDGAA RCLETLRLQN KICNCRPLEF
410 420 430 440 450
NTRLLEVASS IGAKFLVRKI RCRLALIYRA LGDEDQYNTH FRLANQTDAA
460 470 480 490 500
LGLNCGACGE LLGLRPENLE ALPCAHILHA RCAYEILRRR EKNAPRSCPA
510 520 530 540 550
CNKLISSRTH FCGSVPVESE STDRCVTAAS TFNTNSLSVD GLLGINSDIL
560 570 580 590 600
LPSAAFCYVK NPALDTENSA LLSPKVIYHS NLSLASLSMR ASSLTIDSGQ
NVTSSV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014135 Genomic DNA Translation: AAF59332.2 AE014135 Genomic DNA Translation: AAF59333.2 AY051576 mRNA Translation: AAK93000.1 |
RefSeqi | NP_651928.1, NM_143671.3 NP_726586.1, NM_166773.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0089079; FBpp0088148; FBgn0039911 FBtr0089080; FBpp0088149; FBgn0039911 |
GeneIDi | 43800 |
KEGGi | dme:Dmel_CG1909 |
UCSCi | CG1909-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014135 Genomic DNA Translation: AAF59332.2 AE014135 Genomic DNA Translation: AAF59333.2 AY051576 mRNA Translation: AAK93000.1 |
RefSeqi | NP_651928.1, NM_143671.3 NP_726586.1, NM_166773.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q7K4Y8, 4 interactors |
STRINGi | 7227.FBpp0088148 |
Genome annotation databases
EnsemblMetazoai | FBtr0089079; FBpp0088148; FBgn0039911 FBtr0089080; FBpp0088149; FBgn0039911 |
GeneIDi | 43800 |
KEGGi | dme:Dmel_CG1909 |
UCSCi | CG1909-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0039911, CG1909 |
Phylogenomic databases
eggNOGi | KOG1941, Eukaryota |
GeneTreei | ENSGT00390000016785 |
HOGENOMi | CLU_030911_1_0_1 |
OMAi | QGAYKIA |
OrthoDBi | 1245397at2759 |
Miscellaneous databases
BioGRID-ORCSi | 43800, 0 hits in 1 CRISPR screen |
GenomeRNAii | 43800 |
Gene expression databases
Bgeei | FBgn0039911, Expressed in head and 20 other tissues |
Family and domain databases
Gene3Di | 1.25.40.10, 2 hits 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR019568, Rapsyn_myristoylation/link_N IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF10579, Rapsyn_N, 1 hit |
SUPFAMi | SSF48452, SSF48452, 2 hits |
PROSITEi | View protein in PROSITE PS50293, TPR_REGION, 1 hit PS50089, ZF_RING_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q7K4Y8_DROME | |
Accessioni | Q7K4Y8Primary (citable) accession number: Q7K4Y8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 3, 2006 |
Last sequence update: | October 3, 2006 | |
Last modified: | February 10, 2021 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |