The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - Q7K2W3 (Q7K2W3_DROME)
Protein
Submitted name:
GH04538p
Gene
Dmel\CG8785
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- amino acid transmembrane transporter activity Source: FlyBase
GO - Biological processi
- amino acid transmembrane transport Source: FlyBase
Enzyme and pathway databases
Reactomei | R-DME-352230, Amino acid transport across the plasma membrane R-DME-428559, Proton-coupled neutral amino acid transporters R-DME-71240, Tryptophan catabolism |
Names & Taxonomyi
Protein namesi | Submitted name: GH04538pImportedSubmitted name: Uncharacterized protein, isoform AImportedSubmitted name: Uncharacterized protein, isoform BImported |
Gene namesi | Name:Dmel\CG8785Imported ORF Names:CG8785Imported, Dmel_CG8785Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0033760, CG8785 |
VEuPathDBi | VectorBase:FBgn0033760 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 93 – 115 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 157 – 181 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 193 – 210 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 217 – 239 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 259 – 277 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 289 – 315 | HelicalSequence analysisAdd BLAST | 27 | |
Transmembranei | 342 – 360 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 381 – 398 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 404 – 424 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 445 – 467 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 63 – 463 | Aa_transInterPro annotationAdd BLAST | 401 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 33 | DisorderedSequence analysisAdd BLAST | 33 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 10 – 33 | Polar residuesSequence analysisAdd BLAST | 24 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG1304, Eukaryota |
HOGENOMi | CLU_009646_0_1_1 |
OMAi | ETVYLWP |
OrthoDBi | 464614at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR013057, AA_transpt_TM |
Pfami | View protein in Pfam PF01490, Aa_trans, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7K2W3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADNKGFTPD GQESLPSAPT VENPPPYTNA INDFNSKANL TEKELSLTDD
60 70 80 90 100
PYHPFEHRDP NGASAGGALA HLLKSSLGTG ILAMPMAFHN AGLAFGMAMT
110 120 130 140 150
LIVGFLCTHC VHILVKTSHD ICRDAKVSAL GFAETAEKVF EYGPKGMRPY
160 170 180 190 200
SNFAKQFVDI GLMATYYAAA CVYIVFIATS FHDVINYDLK INWDVRIYIA
210 220 230 240 250
LTVIPCLLIG QIRDLKWLVP FSMMANIFIV VTFAITLYYM FDEPLVYSDK
260 270 280 290 300
PLIAKAAHIP LFFATVIFAM EGIGVVMPVE NSMRKPQHFL GCPGVLNIAM
310 320 330 340 350
VTVVSLYAII GFFGYVRFGD QVRGSITLNL PEGAWLGDTA KLLMAVAILF
360 370 380 390 400
TFGLQFYVPN EILWRKISHK FSPEKHNITQ ILLRSGIILL SGGVAAAIPN
410 420 430 440 450
LEPFISLVGA VFFSLLGIFV PSFVETVYLW PDRLGVCKWK LVKNIFLGVF
460 470
SILALVAGAV ASINEIIEMY SDDD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013599 Genomic DNA Translation: AAF58478.2 AY060621 mRNA Translation: AAL28169.1 AE013599 Genomic DNA Translation: AAM68639.1 |
RefSeqi | NP_610804.1, NM_136960.3 NP_725205.1, NM_165932.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0087881; FBpp0086994; FBgn0033760 FBtr0087882; FBpp0086995; FBgn0033760 |
GeneIDi | 36391 |
KEGGi | dme:Dmel_CG8785 |
UCSCi | CG8785-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013599 Genomic DNA Translation: AAF58478.2 AY060621 mRNA Translation: AAL28169.1 AE013599 Genomic DNA Translation: AAM68639.1 |
RefSeqi | NP_610804.1, NM_136960.3 NP_725205.1, NM_165932.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7227.FBpp0086994 |
Protocols and materials databases
DNASUi | 36391 |
Genome annotation databases
EnsemblMetazoai | FBtr0087881; FBpp0086994; FBgn0033760 FBtr0087882; FBpp0086995; FBgn0033760 |
GeneIDi | 36391 |
KEGGi | dme:Dmel_CG8785 |
UCSCi | CG8785-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0033760, CG8785 |
VEuPathDBi | VectorBase:FBgn0033760 |
Phylogenomic databases
eggNOGi | KOG1304, Eukaryota |
HOGENOMi | CLU_009646_0_1_1 |
OMAi | ETVYLWP |
OrthoDBi | 464614at2759 |
Enzyme and pathway databases
Reactomei | R-DME-352230, Amino acid transport across the plasma membrane R-DME-428559, Proton-coupled neutral amino acid transporters R-DME-71240, Tryptophan catabolism |
Miscellaneous databases
BioGRID-ORCSi | 36391, 0 hits in 3 CRISPR screens |
ChiTaRSi | CG8785, fly |
GenomeRNAii | 36391 |
Gene expression databases
Bgeei | FBgn0033760, Expressed in antenna and 30 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR013057, AA_transpt_TM |
Pfami | View protein in Pfam PF01490, Aa_trans, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q7K2W3_DROME | |
Accessioni | Q7K2W3Primary (citable) accession number: Q7K2W3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 3, 2006 |
Last sequence update: | October 3, 2006 | |
Last modified: | January 19, 2022 | |
This is version 135 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |