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Protein
Submitted name:

GH23780p

Gene

ND-15

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductaseImported
LigandUbiquinoneImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
GH23780pImported
Submitted name:
MIP04232pImported
Submitted name:
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform AImported
Submitted name:
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform BImported
Submitted name:
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform CImported
Submitted name:
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform DImported
Submitted name:
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform FImported
Submitted name:
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform GImported
Submitted name:
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform JImported (EC:1.6.99.3Imported)
Submitted name:
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform KImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ND-15Imported
Synonyms:CG11455-RBImported, CG3436Imported, Dmel\CG11455Imported, NIPMImported
ORF Names:CG11455Imported, Dmel_CG11455Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0031228 ND-15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0031228 Expressed in 54 organ(s), highest expression level in head

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q7K1C0, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0297500

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4110 Eukaryota
ENOG41123TD LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000176706

KEGG Orthology (KO)

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KOi
K03938

Identification of Orthologs from Complete Genome Data

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OMAi
DHFQWNR

Database of Orthologous Groups

More...
OrthoDBi
EOG091G1CDO

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019342 NADH_UbQ_OxRdtase_FeS-su5

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10200 Ndufs5, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q7K1C0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLTPFLRLP LTDLTGCLIN HQTYDKCGKF EMKMMECFEA YGLERGKREC
60 70 80 90 100
ADLISDFQEC VGMQKQLMRF HAMRNERYKQ WLKGERKGQE FFADPPRVDA

Y
Length:101
Mass (Da):11,998
Last modified:October 17, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8FEABA1157328E21
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PBY4M9PBY4_DROME
NADH dehydrogenase (Ubiquinone) 15 ...
ND-15 Dmel\CG11455, NIPM, CG11455, Dmel_CG11455
70Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF51538.1
AY069186 mRNA Translation: AAL39331.1
AE014134 Genomic DNA Translation: AAN10510.1
BT081978 mRNA Translation: ACO53093.1
AE014134 Genomic DNA Translation: ACZ94133.1
AE014134 Genomic DNA Translation: ACZ94134.1
AE014134 Genomic DNA Translation: AFH03492.1
AE014134 Genomic DNA Translation: AGB92329.1
AE014134 Genomic DNA Translation: AGB92332.1
AE014134 Genomic DNA Translation: AGB92333.1

NCBI Reference Sequences

More...
RefSeqi
NP_001162841.1, NM_001169370.2
NP_001162842.1, NM_001169371.2
NP_001245815.1, NM_001258886.1
NP_001259792.1, NM_001272863.1
NP_001259795.1, NM_001272866.1
NP_001259796.1, NM_001272867.1
NP_722612.1, NM_164371.3
NP_722613.1, NM_164372.3

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Dm.21236

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0078117; FBpp0077776; FBgn0031228
FBtr0078118; FBpp0077777; FBgn0031228
FBtr0301886; FBpp0291100; FBgn0031228
FBtr0301887; FBpp0291101; FBgn0031228
FBtr0306542; FBpp0297500; FBgn0031228
FBtr0330638; FBpp0303488; FBgn0031228
FBtr0330641; FBpp0303491; FBgn0031228
FBtr0330642; FBpp0303492; FBgn0031228

Database of genes from NCBI RefSeq genomes

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GeneIDi
33179

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
dme:Dmel_CG11455

UCSC genome browser

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UCSCi
CG11455-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF51538.1
AY069186 mRNA Translation: AAL39331.1
AE014134 Genomic DNA Translation: AAN10510.1
BT081978 mRNA Translation: ACO53093.1
AE014134 Genomic DNA Translation: ACZ94133.1
AE014134 Genomic DNA Translation: ACZ94134.1
AE014134 Genomic DNA Translation: AFH03492.1
AE014134 Genomic DNA Translation: AGB92329.1
AE014134 Genomic DNA Translation: AGB92332.1
AE014134 Genomic DNA Translation: AGB92333.1
RefSeqiNP_001162841.1, NM_001169370.2
NP_001162842.1, NM_001169371.2
NP_001245815.1, NM_001258886.1
NP_001259792.1, NM_001272863.1
NP_001259795.1, NM_001272866.1
NP_001259796.1, NM_001272867.1
NP_722612.1, NM_164371.3
NP_722613.1, NM_164372.3
UniGeneiDm.21236

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

IntActiQ7K1C0, 1 interactor
STRINGi7227.FBpp0297500

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0078117; FBpp0077776; FBgn0031228
FBtr0078118; FBpp0077777; FBgn0031228
FBtr0301886; FBpp0291100; FBgn0031228
FBtr0301887; FBpp0291101; FBgn0031228
FBtr0306542; FBpp0297500; FBgn0031228
FBtr0330638; FBpp0303488; FBgn0031228
FBtr0330641; FBpp0303491; FBgn0031228
FBtr0330642; FBpp0303492; FBgn0031228
GeneIDi33179
KEGGidme:Dmel_CG11455
UCSCiCG11455-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
33179
FlyBaseiFBgn0031228 ND-15

Phylogenomic databases

eggNOGiKOG4110 Eukaryota
ENOG41123TD LUCA
GeneTreeiENSGT00940000176706
KOiK03938
OMAiDHFQWNR
OrthoDBiEOG091G1CDO

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ND-15 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
33179

Gene expression databases

BgeeiFBgn0031228 Expressed in 54 organ(s), highest expression level in head

Family and domain databases

InterProiView protein in InterPro
IPR019342 NADH_UbQ_OxRdtase_FeS-su5
PfamiView protein in Pfam
PF10200 Ndufs5, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ7K1C0_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7K1C0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: December 5, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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