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Entry version 128 (03 Jul 2019)
Sequence version 1 (03 Oct 2006)
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Protein
Submitted name:

FI14001p1

Gene

SNF4Agamma

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinaseImported, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FI14001p1Imported
Submitted name:
GH01416pImported
Submitted name:
RE59472pImported
Submitted name:
SNF4/AMP-activated protein kinase gamma subunit, isoform AImported
Submitted name:
SNF4/AMP-activated protein kinase gamma subunit, isoform BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SNF4AgammaImported
Synonyms:0050Imported, 0127Imported, 19Imported, 42Imported, AMPgammaImported, AMPKImported, AMPK&ggrImported, AMPK-&ggrImported, AMPKgammaImported, anon-WO0118547.338Imported, anon-WO0118547.575Imported, anon-WO0257455.21Imported, CG5806Imported, Dmel\CG17299Imported, EP3015bImported, FBgn0025803Imported, l(3)S005042Imported, l(3)S012719Imported, loeImported, loeIImported, SNF4Imported, snf4Imported, SNF4AImported, SNF4aImported, SNF4A-gammaImported, SNF4AgImported, SNF4Agamma-RBImported, SNF4gammaImported, SnfgImported, SnfgammaImported
ORF Names:CG17299Imported, Dmel_CG17299Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0264357 SNF4Agamma

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0264357 Expressed in 41 organ(s), highest expression level in oviduct (Drosophila)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini485 – 547CBSInterPro annotationAdd BLAST63
Domaini564 – 624CBSInterPro annotationAdd BLAST61
Domaini639 – 699CBSInterPro annotationAdd BLAST61
Domaini710 – 770CBSInterPro annotationAdd BLAST61

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 47DisorderedSequence analysisAdd BLAST47
Regioni62 – 293DisorderedSequence analysisAdd BLAST232
Regioni321 – 346DisorderedSequence analysisAdd BLAST26
Regioni798 – 929DisorderedSequence analysisAdd BLAST132

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi128 – 185PolyampholyteSequence analysisAdd BLAST58
Compositional biasi232 – 253PolyampholyteSequence analysisAdd BLAST22
Compositional biasi254 – 275PolarSequence analysisAdd BLAST22
Compositional biasi321 – 335PolarSequence analysisAdd BLAST15
Compositional biasi799 – 817PolarSequence analysisAdd BLAST19
Compositional biasi821 – 845PolyampholyteSequence analysisAdd BLAST25
Compositional biasi846 – 876PolarSequence analysisAdd BLAST31
Compositional biasi887 – 916PolyampholyteSequence analysisAdd BLAST30

Keywords - Domaini

CBS domainPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1764 Eukaryota
COG0517 LUCA

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039170 AMPKG-2
IPR000644 CBS_dom

The PANTHER Classification System

More...
PANTHERi
PTHR13780:SF122 PTHR13780:SF122, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00571 CBS, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00116 CBS, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51371 CBS, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q7JQX9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSSAGGASG GSNYEDVAAA RRGRFRVTSS TPQGPPETTL GRFRLMPTSN
60 70 80 90 100
YGAISPILQR GRFAVIPEEP QAGSPALGTP PPGGRTARSP SPEWDFDIEQ
110 120 130 140 150
EQDGSLGGAG RMPGSRPSSA PAEPNAKAAK KAYKKMEKEQ RRQEKEQSRR
160 170 180 190 200
EKEARKLERE TARRNEREAA KLEKINRHSE KISRSTERMA MAGVGSRSGS
210 220 230 240 250
LERRRSGEDS PVLNQSTVHG IASPNRRPTI FDVFRPRAKS DAKRQKEKHL
260 270 280 290 300
LDPSSADSSA TSSTYSVSGG TGPATSSAAG GAGGAAAAAG QGAAGGAGGL
310 320 330 340 350
MNSMKVAMQN FSHRQHPAVT ITSADGTQST AKSKYKDGSA HPHQGSDAQY
360 370 380 390 400
YHTVTAVRPN SSQRSPMTKV MDLFRHRSSS VVSEADKRKA RAAAHQQQLA
410 420 430 440 450
VQSAHMRRAS ADLEKRRASV GAAGRGLRGD GTLDPHHAAI LFRDSRGLPV
460 470 480 490 500
ADPFLEKVNL SDLEEDDSQI FVKFFRFHKC YDLIPTSAKL VVFDTQLLVK
510 520 530 540 550
KAFYALVYNG VRAAPLWDSE KQQFVGMLTI TDFIKILQMY YKSPNASMEQ
560 570 580 590 600
LEEHKLDTWR SVLHNQVMPL VSIGPDASLY DAIKILIHSR IHRLPVIDPA
610 620 630 640 650
TGNVLYILTH KRILRFLFLY INELPKPAYM QKSLRELKIG TYNNIETADE
660 670 680 690 700
TTSIITALKK FVERRVSALP LVDSDGRLVD IYAKFDVINL AAEKTYNDLD
710 720 730 740 750
VSLRKANEHR NEWFEGVQKC NLDESLYTIM ERIVRAEVHR LVVVDENRKV
760 770 780 790 800
IGIISLSDIL LYLVLRPSGE GVGGSESSLR ASDPVLLRKV AEVEIPATAA
810 820 830 840 850
AATTTTPPRS PSAGSGNRSL IEDIPEEETA PARSDDADSD NNKSASEDKA
860 870 880 890 900
NNNQHDQTTT AATANGDSNN SPVEVSFADE AQEEEAADQV ERSNCDDDDQ
910 920 930 940
PALAEIERKN ASMDDDEDDG MSSAVSAASA LGQSLTPAAQ EMALVSE
Length:947
Mass (Da):103,086
Last modified:October 3, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37FE8D66ED4E5D69
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q0KI34Q0KI34_DROME
SNF4/AMP-activated protein kinase g...
SNF4Agamma 0050, 0127, 19, 42, AMPgamma
538Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9VDD2Q9VDD2_DROME
LD22662p
SNF4Agamma 0050, 0127, 19, 42, AMPgamma
1,400Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A1A703A1A703_DROME
IP17340p
SNF4Agamma 0050, 0127, 19, 42, AMPgamma
614Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8I0A1Q8I0A1_DROME
LD30628p
SNF4Agamma 0050, 0127, 19, 42, AMPgamma
814Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8SXT8Q8SXT8_DROME
RE22690p
SNF4Agamma 0050, 0127, 19, 42, AMPgamma
906Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55860.2
AE014297 Genomic DNA Translation: AAN13851.1
BT003626 mRNA Translation: AAO39629.1
BT010233 mRNA Translation: AAQ23551.1
BT120301 mRNA Translation: ADC53518.1

NCBI Reference Sequences

More...
RefSeqi
NP_536757.2, NM_080509.3
NP_732594.1, NM_169946.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0084018; FBpp0083421; FBgn0264357
FBtr0084019; FBpp0083422; FBgn0264357

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
42515

UCSC genome browser

More...
UCSCi
CG17299-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55860.2
AE014297 Genomic DNA Translation: AAN13851.1
BT003626 mRNA Translation: AAO39629.1
BT010233 mRNA Translation: AAQ23551.1
BT120301 mRNA Translation: ADC53518.1
RefSeqiNP_536757.2, NM_080509.3
NP_732594.1, NM_169946.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0084018; FBpp0083421; FBgn0264357
FBtr0084019; FBpp0083422; FBgn0264357
GeneIDi42515
UCSCiCG17299-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
42515
FlyBaseiFBgn0264357 SNF4Agamma

Phylogenomic databases

eggNOGiKOG1764 Eukaryota
COG0517 LUCA

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SNF4Agamma fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
42515

Gene expression databases

BgeeiFBgn0264357 Expressed in 41 organ(s), highest expression level in oviduct (Drosophila)

Family and domain databases

InterProiView protein in InterPro
IPR039170 AMPKG-2
IPR000644 CBS_dom
PANTHERiPTHR13780:SF122 PTHR13780:SF122, 1 hit
PfamiView protein in Pfam
PF00571 CBS, 3 hits
SMARTiView protein in SMART
SM00116 CBS, 4 hits
PROSITEiView protein in PROSITE
PS51371 CBS, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ7JQX9_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7JQX9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: July 3, 2019
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
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