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Entry version 136 (11 Dec 2019)
Sequence version 1 (05 Jul 2004)
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Protein

Abscisic-aldehyde oxidase

Gene

AAO3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In higher plants aldehyde oxidases (AO) appear to be homo- and heterodimeric assemblies of AO subunits with probably different physiological functions. AO-delta seems to be involved in the last step of abscisic acid biosynthesis, at least in leaves and seeds. In vitro, AO-delta oxidizes abscisic aldehyde to abscisic acid (ABA). In vitro, AO-delta also uses indole-3-aldehyde (IAld), benzaldehyde, 1-naphthaldehyde and cinnamaldehyde as substrate; the AAO2-AAO3 dimer also uses abscisic aldehyde as substrate.5 Publications

Miscellaneous

In vitro, cannot discriminate between (+) and (-) enantiomers of abscisic acid and leads respectively to (+) and (-) cis-ABA.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

All these kinetic values were obtained with AO-delta dimer.
  1. KM=0.51 µM for abscisic aldehyde1 Publication
  2. KM=34 µM for indole-3-aldehyde1 Publication
  3. KM=44 µM for benzaldehyde1 Publication
  4. KM=1.8 µM for 1-naphthaldehyde1 Publication
  5. KM=700 µM for cinnamaldehyde1 Publication

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi40Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation1
    Metal bindingi45Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation1
    Metal bindingi48Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation1

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionOxidoreductase
    Biological processAbscisic acid biosynthesis, Auxin biosynthesis
    Ligand2Fe-2S, FAD, Flavoprotein, Iron, Iron-sulfur, Metal-binding, Molybdenum, NAD

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    ARA:AT2G27150-MONOMER
    MetaCyc:AT2G27150-MONOMER

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    1.2.3.14 399

    SABIO-RK: Biochemical Reaction Kinetics Database

    More...
    SABIO-RKi
    Q7G9P4

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Abscisic-aldehyde oxidase (EC:1.2.3.14)
    Alternative name(s):
    Aldehyde oxidase 3
    Short name:
    AO-3
    Short name:
    AtAO-3
    Short name:
    AtAO4
    Indole-3-acetaldehyde oxidase (EC:1.2.3.7)
    Short name:
    IAA oxidase
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:AAO3
    Synonyms:AO4
    Ordered Locus Names:At2g27150
    ORF Names:F20F1.2
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

    Organism-specific databases

    Arabidopsis Information Portal

    More...
    Araporti
    AT2G27150

    The Arabidopsis Information Resource

    More...
    TAIRi
    locus:2045149 AT2G27150

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Cytoplasm

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    <p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

    Impaired abscisic acid (ABA) biosynthesis.1 Publication

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi821 – 826LQRPVK → WDLDQ in aao3-3; wilty phenotype in rosette leaves, reduced ABA levels, reduced dormancy, abnormal water loss and abnormal response to water deficit. 1 Publication6

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001661111 – 1332Abscisic-aldehyde oxidaseAdd BLAST1332

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q7G9P4

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q7G9P4

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    Q7G9P4

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed in vascular tissues of all organs, particularly in phloem companion cells and xylem parenchymatic cells. Highly expressed in roots and rosettes, and to lower extent in seedlings, stems and flowers. Expressed at very low levels in siliques and dry seeds. Also detected in root dividing cells (tips and primordia), in mesophyll cells and inside the guard cells.7 Publications

    <p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    Transcripts are induced by dehydration, in rosettes but not in roots. Induction by cold, ABA, sodium chloride (NaCl) and polyethylene glycol (PEG) is dependent of the zeaxanthin epoxidase ABA1 protein (ZEP). Induction by glucose requires the short chain alcohol dehydrogenase ABA2 protein. Repressed by mannitol.5 Publications

    Gene expression databases

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q7G9P4 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q7G9P4 AT

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Aldehyde oxidases (AO) are homodimers and heterodimers of AO subunits. AO-delta is a AAO3 homodimer. AAO3 also forms a dimer with AAO2.

    Interacts with PUB44, and this interaction probably results in targeting of this protein to the proteasome.

    3 Publications

    GO - Molecular functioni

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    3702.AT2G27150.2

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q7G9P4

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 882Fe-2S ferredoxin-typePROSITE-ProRule annotationAdd BLAST88
    Domaini219 – 400FAD-binding PCMH-typePROSITE-ProRule annotationAdd BLAST182

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the xanthine dehydrogenase family.Curated

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0430 Eukaryota
    COG4630 LUCA
    COG4631 LUCA

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000191197

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q7G9P4

    KEGG Orthology (KO)

    More...
    KOi
    K09842

    Database of Orthologous Groups

    More...
    OrthoDBi
    48717at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q7G9P4

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR002888 2Fe-2S-bd
    IPR036884 2Fe-2S-bd_dom_sf
    IPR036010 2Fe-2S_ferredoxin-like_sf
    IPR001041 2Fe-2S_ferredoxin-type
    IPR006058 2Fe2S_fd_BS
    IPR000674 Ald_Oxase/Xan_DH_a/b
    IPR036856 Ald_Oxase/Xan_DH_a/b_sf
    IPR016208 Ald_Oxase/xanthine_DH
    IPR008274 AldOxase/xan_DH_Mopterin-bd
    IPR037165 AldOxase/xan_DH_Mopterin-bd_sf
    IPR005107 CO_DH_flav_C
    IPR036683 CO_DH_flav_C_dom_sf
    IPR016166 FAD-bd_PCMH
    IPR036318 FAD-bd_PCMH-like_sf
    IPR002346 Mopterin_DH_FAD-bd

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF01315 Ald_Xan_dh_C, 1 hit
    PF02738 Ald_Xan_dh_C2, 1 hit
    PF03450 CO_deh_flav_C, 1 hit
    PF00941 FAD_binding_5, 1 hit
    PF00111 Fer2, 1 hit
    PF01799 Fer2_2, 1 hit

    PIRSF; a whole-protein classification database

    More...
    PIRSFi
    PIRSF000127 Xanthine_DH, 1 hit

    Simple Modular Architecture Research Tool; a protein domain database

    More...
    SMARTi
    View protein in SMART
    SM01008 Ald_Xan_dh_C, 1 hit
    SM01092 CO_deh_flav_C, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF47741 SSF47741, 1 hit
    SSF54292 SSF54292, 1 hit
    SSF54665 SSF54665, 1 hit
    SSF55447 SSF55447, 1 hit
    SSF56003 SSF56003, 1 hit
    SSF56176 SSF56176, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS00197 2FE2S_FER_1, 1 hit
    PS51085 2FE2S_FER_2, 1 hit
    PS51387 FAD_PCMH, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

    Q7G9P4-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MDLEFAVNGE RFKIDSVDPS TTLLEFLRLN TPFKSVKLGC GEGGCGACLV
    60 70 80 90 100
    VLSKYDPELD QVKECCINSC LTLLCSVNGC SITTSEGLGN TKKGFHPIHK
    110 120 130 140 150
    RFAGFHASQC GFCTPGMCIS LYSSLANAEN NSSKDFTVSE AEKSVSGNLC
    160 170 180 190 200
    RCTGYRPIVD ACKSFASDVD IEDLGLNSFW KKGESKEVMF KNLPPYNPKD
    210 220 230 240 250
    HLVTFPEFLK KKEKVDNGSD HLKYRWTTPF SVAELHNIME AANSGDSLKL
    260 270 280 290 300
    VVGNTGTGYY KDEERFDRYI DISNIPEMSM IKKDEKGIEI GAAVTISNAI
    310 320 330 340 350
    DALEKESKSS YVFKKMATHM EKIGNRSIRN SGSIGGNLVM AQSRKFPSDV
    360 370 380 390 400
    TTLLLAVDAS VYMLNGRKTE KVTLQEFLEL SPVLDSKRVL LKVEIPSWTA
    410 420 430 440 450
    PSGDDTEFLF ESYRAAPRSI GNALPYLNAA FLALVSRQEA SRKGVTVEKC
    460 470 480 490 500
    FLAFGSYGGD HSIRAIEVET FLTGKLLSYS VLYEAVGLLK GIIVPGKDTL
    510 520 530 540 550
    HSEYRKSLAV GYLFEFFYPL IESGHRICSL DSGNKHNNSH VDTVKSLPFL
    560 570 580 590 600
    SSSQQVLESN EFKPIGEAVI KVGAALQASG EAVFVDDIPT LPDCLHGAFI
    610 620 630 640 650
    YSTEPLAKIK SLSFRENVTP TGVFAVLTFK DIPQQGQNIG SKTLFGPGPL
    660 670 680 690 700
    FADELTRCAG QRIALVVADT QKHADMAAKL AVVEYDTKNL EQPILTVEDA
    710 720 730 740 750
    VKRSSFFEVH PMFYPEPVGD VIKGMEEAER KIISSELRLG SQYFFYMEPQ
    760 770 780 790 800
    TALALPDEDN CVKVFSSSQA PEYVHSVIAT CLGIQEHNVR VITRRVGGGF
    810 820 830 840 850
    GGKAVKSMPV ATACALGAYK LQRPVKMFLN RKTDMIMAGG RHPMKINYNV
    860 870 880 890 900
    GFRSDGKLTA LELTMLIDAG LEPDVSPIMP RNIMGPLRKY DWGALSFDVK
    910 920 930 940 950
    VCKTNCLSRT AMRAPGEVQG SYIAESIIEN VASSLQMDVD AVRKINLHTY
    960 970 980 990 1000
    DSLRKFYNHI AGDPDEYTLP LLWEKLEISS KFKERSEMVK EFNLCNVWRK
    1010 1020 1030 1040 1050
    RGISRVPIVH QVMQRPTPGK VSILSDGSVV VEVGGIEIGQ GLWTKVQQMV
    1060 1070 1080 1090 1100
    AYGLGMVKCE GNEKLLDRIR VVQSDTLGMI QGGFTAGSTT SESSCEAVRL
    1110 1120 1130 1140 1150
    CCVILVERLK PIMDQMMMEK SGSVTWNILI QQAYGQYINL SASTLYKPEY
    1160 1170 1180 1190 1200
    SSMEYLNYGV GVSEVEVDLV TGKTEILRSD IIYDCGKSLN PAVDLGQTEG
    1210 1220 1230 1240 1250
    AFVQGIGFFM MEEYTTDEKG LVVQQGTWDY KIPTVDTIPK HFNVEIVNTG
    1260 1270 1280 1290 1300
    HHKNRVLSSK ASGEPPLLLA ASVHCATRSA IREARKHSLS SNFIDGSDSE
    1310 1320 1330
    FELPVPATMP VVKSLCGLYS VEKYLQGKIK GQ
    Length:1,332
    Mass (Da):146,701
    Last modified:July 5, 2004 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i084ED4BEE64B121B
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    A0A1P8AZK7A0A1P8AZK7_ARATH
    Abscisic aldehyde oxidase 3
    AAO3 ABSCISIC ALDEHYDE OXIDASE 3, abscisic aldehyde oxidase 3, Aldehyde oxidase delta, AOdelta, At-AO3
    1,216Annotation score:

    Annotation score:2 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A1P8AZL3A0A1P8AZL3_ARATH
    Abscisic aldehyde oxidase 3
    AAO3 ABSCISIC ALDEHYDE OXIDASE 3, abscisic aldehyde oxidase 3, Aldehyde oxidase delta, AOdelta, At-AO3
    1,060Annotation score:

    Annotation score:2 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A1P8AZL6A0A1P8AZL6_ARATH
    Abscisic aldehyde oxidase 3
    AAO3 ABSCISIC ALDEHYDE OXIDASE 3, abscisic aldehyde oxidase 3, Aldehyde oxidase delta, AOdelta, At-AO3
    1,176Annotation score:

    Annotation score:2 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AB016622 mRNA Translation: BAA82672.1
    AC007154 Genomic DNA Translation: AAD22498.1
    CP002685 Genomic DNA Translation: AEC07944.1
    CP002685 Genomic DNA Translation: AEC07945.1
    AB010080 mRNA Translation: BAA28630.1

    Protein sequence database of the Protein Information Resource

    More...
    PIRi
    D84669
    T52176

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001077966.1, NM_001084497.1
    NP_180283.1, NM_128273.3

    Genome annotation databases

    Ensembl plant genome annotation project

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    EnsemblPlantsi
    AT2G27150.1; AT2G27150.1; AT2G27150
    AT2G27150.2; AT2G27150.2; AT2G27150

    Database of genes from NCBI RefSeq genomes

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    GeneIDi
    817257

    Gramene; a comparative resource for plants

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    Gramenei
    AT2G27150.1; AT2G27150.1; AT2G27150
    AT2G27150.2; AT2G27150.2; AT2G27150

    KEGG: Kyoto Encyclopedia of Genes and Genomes

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    KEGGi
    ath:AT2G27150

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AB016622 mRNA Translation: BAA82672.1
    AC007154 Genomic DNA Translation: AAD22498.1
    CP002685 Genomic DNA Translation: AEC07944.1
    CP002685 Genomic DNA Translation: AEC07945.1
    AB010080 mRNA Translation: BAA28630.1
    PIRiD84669
    T52176
    RefSeqiNP_001077966.1, NM_001084497.1
    NP_180283.1, NM_128273.3

    3D structure databases

    SMRiQ7G9P4
    ModBaseiSearch...

    Protein-protein interaction databases

    STRINGi3702.AT2G27150.2

    PTM databases

    iPTMnetiQ7G9P4

    Proteomic databases

    PaxDbiQ7G9P4
    PRIDEiQ7G9P4

    Genome annotation databases

    EnsemblPlantsiAT2G27150.1; AT2G27150.1; AT2G27150
    AT2G27150.2; AT2G27150.2; AT2G27150
    GeneIDi817257
    GrameneiAT2G27150.1; AT2G27150.1; AT2G27150
    AT2G27150.2; AT2G27150.2; AT2G27150
    KEGGiath:AT2G27150

    Organism-specific databases

    AraportiAT2G27150
    TAIRilocus:2045149 AT2G27150

    Phylogenomic databases

    eggNOGiKOG0430 Eukaryota
    COG4630 LUCA
    COG4631 LUCA
    HOGENOMiHOG000191197
    InParanoidiQ7G9P4
    KOiK09842
    OrthoDBi48717at2759
    PhylomeDBiQ7G9P4

    Enzyme and pathway databases

    BioCyciARA:AT2G27150-MONOMER
    MetaCyc:AT2G27150-MONOMER
    BRENDAi1.2.3.14 399
    SABIO-RKiQ7G9P4

    Miscellaneous databases

    Protein Ontology

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    PROi
    PR:Q7G9P4

    Gene expression databases

    ExpressionAtlasiQ7G9P4 baseline and differential
    GenevisibleiQ7G9P4 AT

    Family and domain databases

    InterProiView protein in InterPro
    IPR002888 2Fe-2S-bd
    IPR036884 2Fe-2S-bd_dom_sf
    IPR036010 2Fe-2S_ferredoxin-like_sf
    IPR001041 2Fe-2S_ferredoxin-type
    IPR006058 2Fe2S_fd_BS
    IPR000674 Ald_Oxase/Xan_DH_a/b
    IPR036856 Ald_Oxase/Xan_DH_a/b_sf
    IPR016208 Ald_Oxase/xanthine_DH
    IPR008274 AldOxase/xan_DH_Mopterin-bd
    IPR037165 AldOxase/xan_DH_Mopterin-bd_sf
    IPR005107 CO_DH_flav_C
    IPR036683 CO_DH_flav_C_dom_sf
    IPR016166 FAD-bd_PCMH
    IPR036318 FAD-bd_PCMH-like_sf
    IPR002346 Mopterin_DH_FAD-bd
    PfamiView protein in Pfam
    PF01315 Ald_Xan_dh_C, 1 hit
    PF02738 Ald_Xan_dh_C2, 1 hit
    PF03450 CO_deh_flav_C, 1 hit
    PF00941 FAD_binding_5, 1 hit
    PF00111 Fer2, 1 hit
    PF01799 Fer2_2, 1 hit
    PIRSFiPIRSF000127 Xanthine_DH, 1 hit
    SMARTiView protein in SMART
    SM01008 Ald_Xan_dh_C, 1 hit
    SM01092 CO_deh_flav_C, 1 hit
    SUPFAMiSSF47741 SSF47741, 1 hit
    SSF54292 SSF54292, 1 hit
    SSF54665 SSF54665, 1 hit
    SSF55447 SSF55447, 1 hit
    SSF56003 SSF56003, 1 hit
    SSF56176 SSF56176, 1 hit
    PROSITEiView protein in PROSITE
    PS00197 2FE2S_FER_1, 1 hit
    PS51085 2FE2S_FER_2, 1 hit
    PS51387 FAD_PCMH, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiALDO3_ARATH
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7G9P4
    Secondary accession number(s): O64429
    , Q7GD73, Q9SIG7, Q9SLZ2
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: July 5, 2004
    Last modified: December 11, 2019
    This is version 136 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
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