Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

HTH-type transcriptional regulator ArcR

Gene

arcR

Organism
Staphylococcus aureus (strain N315)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Positively regulates the expression of the arcABDCR operon under anaerobic conditions, thus playing an essential role in arginine catabolism. May also control the expression of genes encoding proteins which are involved in anaerobic metabolism. Can bind cyclic AMP (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi40 – 129cNMPAdd BLAST90
DNA bindingi188 – 207H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation
LigandcAMP, cAMP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator ArcR
Gene namesi
Name:arcR
Ordered Locus Names:SA2424
OrganismiStaphylococcus aureus (strain N315)
Taxonomic identifieri158879 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000751 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003494131 – 234HTH-type transcriptional regulator ArcRAdd BLAST234

Structurei

3D structure databases

ProteinModelPortaliQ7A381
SMRiQ7A381
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 228HTH crp-typePROSITE-ProRule annotationAdd BLAST74

Phylogenomic databases

HOGENOMiHOG000022896
KOiK21828
OMAiEYLCKNH

Family and domain databases

InterProiView protein in InterPro
IPR018490 cNMP-bd-like
IPR000595 cNMP-bd_dom
IPR012318 HTH_CRP
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00027 cNMP_binding, 1 hit
PF13545 HTH_Crp_2, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF51206 SSF51206, 1 hit
PROSITEiView protein in PROSITE
PS51063 HTH_CRP_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7A381-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTENFILGRN NKLEHELKAL ADYINIPYSI LQPYQSECFV RHYTKGQVIY
60 70 80 90 100
FSPQESSNIY FLIEGNIIRE HYNQNGDVYR YFNKEQVLFP ISNLFHPKEV
110 120 130 140 150
NELCTALTDC TVLGLPRELM AFLCKANDDI FLTLFALIND NEQQHMNYNM
160 170 180 190 200
ALTSKFAKDR IIKLLCHLCQ TVGYDQDEFY EIKQFLTIQL MSDMAGISRE
210 220 230
TAGHIIHELK DEKLVVKDHK NWLVSKHLFN DVCV
Length:234
Mass (Da):27,428
Last modified:July 5, 2004 - v1
Checksum:iA63E59D8A1ED4E1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000018 Genomic DNA Translation: BAB43729.1
PIRiG90070
RefSeqiWP_000138218.1, NC_002745.2

Genome annotation databases

EnsemblBacteriaiBAB43729; BAB43729; BAB43729
KEGGisau:SA2424

Similar proteinsi

Entry informationi

Entry nameiARCR_STAAN
AccessioniPrimary (citable) accession number: Q7A381
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health