UniProtKB - Q79VF7 (Q79VF7_CORGL)
Protein
Protein-export membrane protein SecF
Gene
secF
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
Status
Functioni
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation
GO - Molecular functioni
GO - Biological processi
- intracellular protein transmembrane transport Source: UniProtKB-UniRule
- protein targeting Source: UniProtKB-UniRule
- protein transport by the Sec complex Source: UniProtKB-UniRule
Keywordsi
Biological process | Protein transport, TranslocationUniRule annotationARBA annotation, Transport |
Enzyme and pathway databases
BioCyci | CORYNE:G18NG-11242-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Protein-export membrane protein SecFUniRule annotation |
Gene namesi | Name:secFUniRule annotation Ordered Locus Names:Cgl1657Imported |
Organismi | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)Imported |
Taxonomic identifieri | 196627 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Corynebacteriaceae › Corynebacterium › |
Proteomesi |
|
Subcellular locationi
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 41 – 59 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 162 – 183 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 190 – 211 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 217 – 238 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 276 – 296 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 302 – 325 | HelicalUniRule annotationAdd BLAST | 24 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell membraneUniRule annotationARBA annotation, MembraneInteractioni
Subunit structurei
Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
UniRule annotationProtein-protein interaction databases
STRINGi | 196627.cg1865 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 353 – 403 | DisorderedSequence analysisAdd BLAST | 51 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 353 – 370 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 384 – 403 | PolyampholyteSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | COG0341, Bacteria |
HOGENOMi | CLU_050012_2_0_11 |
OMAi | AFEWRMA |
Family and domain databases
HAMAPi | MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS IPR005665, SecF_bac |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF07549, Sec_GG, 1 hit PF02355, SecD_SecF, 1 hit |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00966, 3a0501s07, 1 hit |
i Sequence
Sequence statusi: Complete.
Q79VF7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTDSQTESLS TQSVKPAKKR SWFNSLYTGD GGIDFIAKTK LWYWITGILL
60 70 80 90 100
VISILFIAIR GFSLSIDFQG GTKMSMPASD YSTEQVEETF TEATGITPEI
110 120 130 140 150
VQIVGSGDAR TLEIYSERLS DEDVEKARLA IYEEYQPLNS EGQPSPDAIG
160 170 180 190 200
NSTVSESWGS TITQRMVLAL IAFLVIAAIY IAFRLEREMA IAAMAALVVD
210 220 230 240 250
GIVIAGIYAV IGLEVSPATV IGLLTVLTFS IYDTVVVFDK VRENTEGFEG
260 270 280 290 300
SRRRTYAEQA NLAVNQTFMR SISTTIISAL PIIALMVVAV WMMGVGTLKD
310 320 330 340 350
LALIQLIGVI EGTFSSVFLA TPLLVSLKNR LSKTKAHTAS VMKLRDGQST
360 370 380 390 400
LIDATPHTNA DASAHGTESD TDGVTPEAPA KRTVSKPIVD DHRSSGTWRP
GRS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000036 Genomic DNA Translation: BAB99050.1 |
RefSeqi | NP_600869.1, NC_003450.3 WP_011014516.1, NC_006958.1 |
Genome annotation databases
EnsemblBacteriai | BAB99050; BAB99050; BAB99050 |
KEGGi | cgl:NCgl1593 |
PATRICi | fig|196627.13.peg.1617 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000036 Genomic DNA Translation: BAB99050.1 |
RefSeqi | NP_600869.1, NC_003450.3 WP_011014516.1, NC_006958.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 196627.cg1865 |
Genome annotation databases
EnsemblBacteriai | BAB99050; BAB99050; BAB99050 |
KEGGi | cgl:NCgl1593 |
PATRICi | fig|196627.13.peg.1617 |
Phylogenomic databases
eggNOGi | COG0341, Bacteria |
HOGENOMi | CLU_050012_2_0_11 |
OMAi | AFEWRMA |
Enzyme and pathway databases
BioCyci | CORYNE:G18NG-11242-MONOMER |
Family and domain databases
HAMAPi | MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS IPR005665, SecF_bac |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF07549, Sec_GG, 1 hit PF02355, SecD_SecF, 1 hit |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00966, 3a0501s07, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q79VF7_CORGL | |
Accessioni | Q79VF7Primary (citable) accession number: Q79VF7 Secondary accession number(s): Q9AE06 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | February 10, 2021 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |