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UniProtKB - Q792Z7 (Q792Z7_MOUSE)
Protein
Submitted name:
D(B) glycoprotein
Gene
H2-D1
Organism
Mus musculus (Mouse)
Status
Functioni
Involved in the presentation of foreign antigens to the immune system.
ARBA annotationGO - Biological processi
- antigen processing and presentation Source: InterPro
- immune response Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: D(B) glycoproteinImportedSubmitted name: H2DImportedSubmitted name: Histocompatibility 2, D region locus 1Imported |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:95896, H2-D1 |
VEuPathDBi | HostDB:ENSMUSG00000073411 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Endoplasmic reticulum
Other locations
- phagocytic vesicle membrane Source: UniProt
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 307 – 330 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | Sequence analysisAdd BLAST | 24 | |
ChainiPRO_5014310802 | 25 – 362 | Sequence analysisAdd BLAST | 338 |
Keywords - PTMi
GlycoproteinARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000073411, Expressed in mammary gland and 317 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 209 – 297 | Ig-likeInterPro annotationAdd BLAST | 89 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 340 – 362 | DisorderedSequence analysisAdd BLAST | 23 |
Sequence similaritiesi
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
HOGENOMi | CLU_047501_1_1_1 |
OMAi | EHENEYL |
OrthoDBi | 1390181at2759 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.30.500.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003597, Ig_C1-set IPR011161, MHC_I-like_Ag-recog IPR037055, MHC_I-like_Ag-recog_sf IPR011162, MHC_I/II-like_Ag-recog IPR001039, MHC_I_a_a1/a2 IPR010579, MHC_I_a_C |
Pfami | View protein in Pfam PF07654, C1-set, 1 hit PF00129, MHC_I, 1 hit PF06623, MHC_I_C, 1 hit |
PRINTSi | PR01638, MHCCLASSI |
SMARTi | View protein in SMART SM00407, IGc1, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit SSF54452, SSF54452, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS00290, IG_MHC, 1 hit |
i Sequence
Sequence statusi: Complete.
Q792Z7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGAMAPRTLL LLLAAALAPT QTRAGPHSMR YFETAVSRPG LEEPRYISVG
60 70 80 90 100
YVDNKEFVRF DSDAENPRYE PRAPWMEQEG PEYWERETQK AKGQEQWFRV
110 120 130 140 150
SLRNLLGYYN QSAGGSHTLQ QMSGCDLGSD WRLLRGYLQF AYEGRDYIAL
160 170 180 190 200
NEDLKTWTAA DMAAQITRRK WEQSGAAEHY KAYLEGECVE WLHRYLKNGN
210 220 230 240 250
ATLLRTDSPK AHVTHHPRSK GEVTLRCWAL GFYPADITLT WQLNGEELTQ
260 270 280 290 300
DMELVETRPA GDGTFQKWAS VVVPLGKEQN YTCRVYHEGL PEPLTLRWEP
310 320 330 340 350
PPSTDSYMVI VAVLGVLGAM AIIGAVVAFV MKRRRNTGGK GGDYALAPGS
360
QSSEMSLRDC KA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007080 Genomic DNA Translation: AAD30178.1 BC132088 mRNA Translation: AAI32089.1 BC132655 mRNA Translation: AAI32656.1 AK159572 mRNA Translation: BAE35194.1 X52490 mRNA Translation: CAA36730.1 |
RefSeqi | NP_034510.3, NM_010380.3 |
Genome annotation databases
GeneIDi | 14964 |
KEGGi | mmu:14964 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007080 Genomic DNA Translation: AAD30178.1 BC132088 mRNA Translation: AAI32089.1 BC132655 mRNA Translation: AAI32656.1 AK159572 mRNA Translation: BAE35194.1 X52490 mRNA Translation: CAA36730.1 |
RefSeqi | NP_034510.3, NM_010380.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
DNASUi | 14964 |
Genome annotation databases
GeneIDi | 14964 |
KEGGi | mmu:14964 |
Organism-specific databases
CTDi | 14964 |
MGIi | MGI:95896, H2-D1 |
VEuPathDBi | HostDB:ENSMUSG00000073411 |
Phylogenomic databases
HOGENOMi | CLU_047501_1_1_1 |
OMAi | EHENEYL |
OrthoDBi | 1390181at2759 |
Miscellaneous databases
BioGRID-ORCSi | 14964, 5 hits in 71 CRISPR screens |
ChiTaRSi | H2-D1, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000073411, Expressed in mammary gland and 317 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.30.500.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003597, Ig_C1-set IPR011161, MHC_I-like_Ag-recog IPR037055, MHC_I-like_Ag-recog_sf IPR011162, MHC_I/II-like_Ag-recog IPR001039, MHC_I_a_a1/a2 IPR010579, MHC_I_a_C |
Pfami | View protein in Pfam PF07654, C1-set, 1 hit PF00129, MHC_I, 1 hit PF06623, MHC_I_C, 1 hit |
PRINTSi | PR01638, MHCCLASSI |
SMARTi | View protein in SMART SM00407, IGc1, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit SSF54452, SSF54452, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS00290, IG_MHC, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q792Z7_MOUSE | |
Accessioni | Q792Z7Primary (citable) accession number: Q792Z7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | January 19, 2022 | |
This is version 169 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |