H2-D1

Functionⁱ

Involved in the presentation of foreign antigens to the immune system.SAAS annotation

GO - Biological processⁱ

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent Source: Ensembl
immune response Source: InterPro
negative regulation of neuron projection development Source: Ensembl
positive regulation of T cell mediated cytotoxicity Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Immunity

Biological process

Immunity

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: D(B) glycoproteinImported Submitted name: H2DImported Submitted name: Histocompatibility 2, D region locus 1Imported Submitted name: MCG22611, isoform CRA_aImported
Gene namesⁱ	Name:H2-D1Imported Synonyms:D(b) geneImported, H2DImported ORF Names:mCG_22611Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:95896 H2-D1

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	307 – 330	HelicalSequence analysisAdd BLAST		24

Keywords - Cellular componentⁱ

Membrane, MHC ISAAS annotation

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 24	Sequence analysisAdd BLAST		24
ChainⁱPRO_5014310802	25 – 362	Sequence analysisAdd BLAST		338

Keywords - PTMⁱ

Disulfide bondSAAS annotation

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000073411 Expressed in 296 organ(s), highest expression level in mammary gland

Bgeeⁱ

ENSMUSG00000073411 Expressed in 296 organ(s), highest expression level in mammary gland

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	209 – 297	Ig-likeInterPro annotationAdd BLAST		89

Sequence similaritiesⁱ

Belongs to the MHC class I family.UniRule annotationSAAS annotation

Keywords - Domainⁱ

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGⁱ	ENOG410II5V Eukaryota ENOG4111K8F LUCA
HOVERGENⁱ	HBG016709
KEGG Orthology (KO) More...KOⁱ	K06751
OMAⁱ	KWVAVEV
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G09OH

Family and domain databases

Gene3Dⁱ	2.60.40.10, 1 hit 3.30.500.10, 1 hit
InterProⁱ	View protein in InterPro IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR003006 Ig/MHC_CS IPR003597 Ig_C1-set IPR011161 MHC_I-like_Ag-recog IPR037055 MHC_I-like_Ag-recog_sf IPR011162 MHC_I/II-like_Ag-recog IPR001039 MHC_I_a_a1/a2 IPR010579 MHC_I_a_C
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07654 C1-set, 1 hit PF00129 MHC_I, 1 hit PF06623 MHC_I_C, 1 hit
PRINTSⁱ	PR01638 MHCCLASSI
SMARTⁱ	View protein in SMART SM00407 IGc1, 1 hit
SUPFAMⁱ	SSF48726 SSF48726, 1 hit SSF54452 SSF54452, 1 hit
PROSITEⁱ	View protein in PROSITE PS50835 IG_LIKE, 1 hit PS00290 IG_MHC, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q792Z7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGAMAPRTLL LLLAAALAPT QTRAGPHSMR YFETAVSRPG LEEPRYISVG 
        60         70         80         90        100
YVDNKEFVRF DSDAENPRYE PRAPWMEQEG PEYWERETQK AKGQEQWFRV 
       110        120        130        140        150
SLRNLLGYYN QSAGGSHTLQ QMSGCDLGSD WRLLRGYLQF AYEGRDYIAL 
       160        170        180        190        200
NEDLKTWTAA DMAAQITRRK WEQSGAAEHY KAYLEGECVE WLHRYLKNGN 
       210        220        230        240        250
ATLLRTDSPK AHVTHHPRSK GEVTLRCWAL GFYPADITLT WQLNGEELTQ 
       260        270        280        290        300
DMELVETRPA GDGTFQKWAS VVVPLGKEQN YTCRVYHEGL PEPLTLRWEP 
       310        320        330        340        350
PPSTDSYMVI VAVLGVLGAM AIIGAVVAFV MKRRRNTGGK GGDYALAPGS 
       360 
QSSEMSLRDC KA

Length:362

Mass (Da):40,836

Last modified:May 10, 2005 - v1

Checksum:ⁱ6EE6AEF97263FA71

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC007080 Genomic DNA Translation: AAD30178.1 BC132088 mRNA Translation: AAI32089.1 BC132655 mRNA Translation: AAI32656.1 AK159572 mRNA Translation: BAE35194.1 X52490 mRNA Translation: CAA36730.1 CH466827 Genomic DNA Translation: EDL06696.1
NCBI Reference Sequences More...RefSeqⁱ	NP_034510.3, NM_010380.3
UniGeneⁱ	Mm.439675

Genome annotation databases

GeneIDⁱ	14964
KEGGⁱ	mmu:14964

Protein	Similar proteins		Species	Score	Length	Source
Q792Z7	H-2 class I histocompatibility antigen, D-B alpha chain	)	MOUSE		362	UniRef100_P01899
MHC class I antigen		MOUSE		359
H-2D cell surface glycoprotein (Fragment)		MOUSE		337
Cell surface glycoprotein (Fragment)		MOUSE		155
H-2D cell surface glycoprotein (Fragment)		MOUSE		206
+11

Protein	Similar proteins		Species	Score	Length	Source
Q792Z7	H-2 class I histocompatibility antigen, D-B alpha chain	)	MOUSE		362	UniRef90_P01899
H-2 class I histocompatibility antigen, L-D alpha chain	)	MOUSE		362
MHC class I antigen		MOUSE		359
H-2D cell surface glycoprotein (Fragment)		MOUSE		337
Cell surface glycoprotein (Fragment)		MOUSE		155
+27

Protein	Similar proteins		Species	Score	Length	Source
Q792Z7	HLA class I histocompatibility antigen, B-8 alpha chain	)	HUMAN		362	UniRef50_P30460
Class I histocompatibility antigen, Gogo-B*0201 alpha chain		GORGO		363
Patr class I histocompatibility antigen, A-5 alpha chain		PANTR		362
H-2 class I histocompatibility antigen, D-B alpha chain	)	MOUSE		362
RT1 class I histocompatibility antigen, AA alpha chain	)	RAT		371
+4464

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC007080 Genomic DNA Translation: AAD30178.1 BC132088 mRNA Translation: AAI32089.1 BC132655 mRNA Translation: AAI32656.1 AK159572 mRNA Translation: BAE35194.1 X52490 mRNA Translation: CAA36730.1 CH466827 Genomic DNA Translation: EDL06696.1
RefSeqⁱ	NP_034510.3, NM_010380.3
UniGeneⁱ	Mm.439675

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	14964
KEGGⁱ	mmu:14964

Organism-specific databases

CTDⁱ	14964
MGIⁱ	MGI:95896 H2-D1

Phylogenomic databases

eggNOGⁱ	ENOG410II5V Eukaryota ENOG4111K8F LUCA
HOVERGENⁱ	HBG016709
KOⁱ	K06751
OMAⁱ	KWVAVEV
OrthoDBⁱ	EOG091G09OH

Miscellaneous databases

ChiTaRSⁱ	H2-D1 mouse
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000073411 Expressed in 296 organ(s), highest expression level in mammary gland

Bgeeⁱ

ENSMUSG00000073411 Expressed in 296 organ(s), highest expression level in mammary gland

Family and domain databases

Gene3Dⁱ	2.60.40.10, 1 hit 3.30.500.10, 1 hit
InterProⁱ	View protein in InterPro IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR003006 Ig/MHC_CS IPR003597 Ig_C1-set IPR011161 MHC_I-like_Ag-recog IPR037055 MHC_I-like_Ag-recog_sf IPR011162 MHC_I/II-like_Ag-recog IPR001039 MHC_I_a_a1/a2 IPR010579 MHC_I_a_C
Pfamⁱ	View protein in Pfam PF07654 C1-set, 1 hit PF00129 MHC_I, 1 hit PF06623 MHC_I_C, 1 hit
PRINTSⁱ	PR01638 MHCCLASSI
SMARTⁱ	View protein in SMART SM00407 IGc1, 1 hit
SUPFAMⁱ	SSF48726 SSF48726, 1 hit SSF54452 SSF54452, 1 hit
PROSITEⁱ	View protein in PROSITE PS50835 IG_LIKE, 1 hit PS00290 IG_MHC, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q792Z7_MOUSE
Accessionⁱ	Q792Z7Primary (citable) accession number: Q792Z7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 10, 2005
	Last sequence update:	May 10, 2005
	Last modified:	November 7, 2018
	This is version 148 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

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UniProtKB - Q792Z7 (Q792Z7_MOUSE)

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D(B) glycoprotein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Keywords - PTMi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ