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UniProtKB - Q791X1 (Q791X1_MOUSE)
Protein
Submitted name:
Cyclin-dependent kinase inhibitor 1C (P57)
Gene
Cdkn1c
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- cyclin-dependent protein serine/threonine kinase inhibitor activity Source: InterPro
- kinase activity Source: UniProtKB-KW
GO - Biological processi
- regulation of mitotic cell cycle Source: InterPro
Keywordsi
Molecular function | KinaseImported, Protein kinase inhibitorARBA annotation, Transferase |
Names & Taxonomyi
Protein namesi | Submitted name: Cyclin-dependent kinase inhibitor 1C (P57)ImportedSubmitted name: p57Kip2 proteinImported |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:104564, Cdkn1c |
VEuPathDBi | HostDB:ENSMUSG00000037664 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000037664, Expressed in dorsal pancreas and 330 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 71 | CDIInterPro annotationAdd BLAST | 51 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 103 – 335 | DisorderedSequence analysisAdd BLAST | 233 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 133 – 147 | Pro residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 218 – 257 | Acidic residuesSequence analysisAdd BLAST | 40 |
Sequence similaritiesi
Belongs to the CDI family.ARBA annotation
Phylogenomic databases
HOGENOMi | CLU_077692_0_0_1 |
OMAi | NNTHITD |
OrthoDBi | 1595421at2759 |
Family and domain databases
Gene3Di | 4.10.365.10, 1 hit |
InterProi | View protein in InterPro IPR003175, CDI_dom IPR044898, CDI_dom_sf IPR029842, CDKN1C |
PANTHERi | PTHR10265:SF44, PTHR10265:SF44, 1 hit |
Pfami | View protein in Pfam PF02234, CDI, 1 hit |
i Sequence
Sequence statusi: Complete.
Q791X1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERLASSDTF PVIARSSACR SLFGPVDHEE LGRELRMRLA ELNAEDQNRW
60 70 80 90 100
DFNFQQDVPL RGPGRLQWME VDSESVPAFY RETVQVGRCR LQLGPRPPPV
110 120 130 140 150
AVAVIPRSGP PAGEAPDGLE EAPEQPPSAP ASAVVAEPTP PATPAPASDL
160 170 180 190 200
TSDPIPEVTL VATSDPTPDP IPDANPDVAT RDGEEQVPEQ VSEQGEESGA
210 220 230 240 250
EPGDELGTEP VSEQGEEQGA EPVEEKDEEP EEEQGAEPVE EQGAEPVEEQ
260 270 280 290 300
NGEPVEEQDE NQEQRGQELK DQPLSGIPGR PAPGTAAANA NDFFAKRKRT
310 320 330
AQENKASNDV PPGCPSPNVA PGVGAVEQTP RKRLR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF160190 Genomic DNA Translation: AAF00983.1 BC005412 mRNA Translation: AAH05412.1 |
RefSeqi | NP_034006.3, NM_009876.4 XP_006508534.1, XM_006508471.3 |
Genome annotation databases
GeneIDi | 12577 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF160190 Genomic DNA Translation: AAF00983.1 BC005412 mRNA Translation: AAH05412.1 |
RefSeqi | NP_034006.3, NM_009876.4 XP_006508534.1, XM_006508471.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 972, 1145 antibodies from 41 providers |
DNASUi | 12577 |
Genome annotation databases
GeneIDi | 12577 |
Organism-specific databases
CTDi | 1028 |
MGIi | MGI:104564, Cdkn1c |
VEuPathDBi | HostDB:ENSMUSG00000037664 |
Phylogenomic databases
HOGENOMi | CLU_077692_0_0_1 |
OMAi | NNTHITD |
OrthoDBi | 1595421at2759 |
Miscellaneous databases
BioGRID-ORCSi | 12577, 0 hits in 63 CRISPR screens |
ChiTaRSi | Cdkn1c, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000037664, Expressed in dorsal pancreas and 330 other tissues |
Family and domain databases
Gene3Di | 4.10.365.10, 1 hit |
InterProi | View protein in InterPro IPR003175, CDI_dom IPR044898, CDI_dom_sf IPR029842, CDKN1C |
PANTHERi | PTHR10265:SF44, PTHR10265:SF44, 1 hit |
Pfami | View protein in Pfam PF02234, CDI, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q791X1_MOUSE | |
Accessioni | Q791X1Primary (citable) accession number: Q791X1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | January 19, 2022 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |