Cyclin-dependent kinase inhibitor 1C (P57)

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• cyclin-dependent protein serine/threonine kinase inhibitor activity Source: InterPro
• kinase activity Source: UniProtKB-KW

GO - Biological processⁱ

• adrenal gland development Source: Ensembl
• aging Source: Ensembl
• camera-type eye development Source: Ensembl
• cell cycle arrest Source: InterPro
• digestive system development Source: Ensembl
• embryonic placenta morphogenesis Source: Ensembl
• genetic imprinting Source: Ensembl
• kidney development Source: Ensembl
• multicellular organism growth Source: Ensembl
• myeloid cell differentiation Source: Ensembl
• negative regulation of transcription by RNA polymerase II Source: Ensembl
• neuron maturation Source: Ensembl
• regulation of exit from mitosis Source: Ensembl
• regulation of lens fiber cell differentiation Source: Ensembl
• skeletal system development Source: Ensembl
• uterus development Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MERLASSDTF PVIARSSACR SLFGPVDHEE LGRELRMRLA ELNAEDQNRW 
        60         70         80         90        100
DFNFQQDVPL RGPGRLQWME VDSESVPAFY RETVQVGRCR LQLGPRPPPV 
       110        120        130        140        150
AVAVIPRSGP PAGEAPDGLE EAPEQPPSAP ASAVVAEPTP PATPAPASDL 
       160        170        180        190        200
TSDPIPEVTL VATSDPTPDP IPDANPDVAT RDGEEQVPEQ VSEQGEESGA 
       210        220        230        240        250
EPGDELGTEP VSEQGEEQGA EPVEEKDEEP EEEQGAEPVE EQGAEPVEEQ 
       260        270        280        290        300
NGEPVEEQDE NQEQRGQELK DQPLSGIPGR PAPGTAAANA NDFFAKRKRT 
       310        320        330 
AQENKASNDV PPGCPSPNVA PGVGAVEQTP RKRLR                 

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ