Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 40 (11 Dec 2019)
Sequence version 1 (15 May 2007)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

ORF 73

Gene
N/A
Organism
Human herpesvirus 8 type M
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ORF 73Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHuman herpesvirus 8 type MImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri435895 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesHerpesviralesHerpesviridaeGammaherpesvirinaeRhadinovirus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q76SB0

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 1021DisorderedSequence analysisAdd BLAST1021
Regioni1143 – 1162DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi24 – 54PolyampholyteSequence analysisAdd BLAST31
Compositional biasi83 – 120Pro-richSequence analysisAdd BLAST38
Compositional biasi157 – 187Pro-richSequence analysisAdd BLAST31
Compositional biasi188 – 216PolarSequence analysisAdd BLAST29
Compositional biasi291 – 324PolyampholyteSequence analysisAdd BLAST34
Compositional biasi325 – 426AcidicSequence analysisAdd BLAST102
Compositional biasi433 – 554PolarSequence analysisAdd BLAST122
Compositional biasi555 – 599PolyampholyteSequence analysisAdd BLAST45
Compositional biasi602 – 723AcidicSequence analysisAdd BLAST122
Compositional biasi724 – 744PolarSequence analysisAdd BLAST21
Compositional biasi745 – 925AcidicSequence analysisAdd BLAST181

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.390, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037007 EBNA1_DNA-bd_sf

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q76SB0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPPGMRLRS GRSTGAPLTR GSCRKRNRSP ERCDLGDDLH LQPRRKHVAD
60 70 80 90 100
SIDGRECGPH TLPIPGSPTV FTSGLPAFVS SPTLPVAPIP SPAPATPLPP
110 120 130 140 150
PALLPPVTTS SSPIPPSHPV SPGTTDTHSP SPALPPTQSP ESSQRPPLSS
160 170 180 190 200
PTGRPDSSTP MRPPPSQQTT PPHSPTTPPP EPPSKSSPDS LAPSTLRSLR
210 220 230 240 250
KRRLSSPQGP STLNPICQSP PVSPPRCDFA NRSVYPPWAT ESPIYVGSSS
260 270 280 290 300
DGDTPPRQPP TSPISIGSSS PSEGSWGDDT AMLVLLAEIA EEASKNEKEC
310 320 330 340 350
SENNQAGEDN GDNEISKESQ VDKDDNDNKD DEEEQETDEE DEEDDEEDDE
360 370 380 390 400
EDDEEDDEED DEEDDEEDDE EDDEEDDEED DEEDDEEEDE EEDEEEDEEE
410 420 430 440 450
EDEEDDDDED NEDEEDDEEE DKKEDEEDGG DGNKTLSIQS SQQQQEPQQQ
460 470 480 490 500
EPQQQEPQQQ EPLQEPQQQE PQQQEPQQQE PLQEPQQQEP QQQEPLQEPQ
510 520 530 540 550
QQEPQQQEPQ QQEPQQQEPQ QQEPQQQEPQ QQEPQQQEPQ QQEPQQQEPQ
560 570 580 590 600
QREPQQREPQ QREPQQREPQ QREPQQREPQ QREPQQREPQ QREPQQQDEQ
610 620 630 640 650
QQDEQQQDEQ QQDEQQQDEQ QQDEQQQDEQ QQDEQQQDEQ QQDEQQQDEQ
660 670 680 690 700
QQDEQQQDEQ QQDEQQQDEQ QQDEQQQDEQ QQDEQQQDEQ QQDEQQQDEQ
710 720 730 740 750
EQQDEQEQQD EQEQQDEQQQ DEQQQQDEQQ QQDEQQQQDE QQQQDEQQQQ
760 770 780 790 800
DEQEQQEEQE QQEEQEQELE EQEQELEDQE QELEEQEQEL EEQEQELEEQ
810 820 830 840 850
EQELEEQEQE LEEQEQELEE QEQELEEQEQ ELEEQEQELE EQEVEEQEQE
860 870 880 890 900
VEEQEQEQEE QELEEVEEQE QEQEEQEEQE LEEVEEQEEQ ELEEVEEQEE
910 920 930 940 950
QELEEVEEQE QQELEEVEEQ EQQGVEQQEQ ETVEEPIILH GSSSEDEMEV
960 970 980 990 1000
DYPVVSTHEQ IASSPPGDNT PDDDPQPGPS REYRYVLRTS PPHRPGVRMR
1010 1020 1030 1040 1050
RVPVTHPKKP HPRYQQPPVP YRQIDDCPAK ARPQHIFYRR FLGKDGRRDP
1060 1070 1080 1090 1100
KCQWKFAVIF WGNDPYGLKK LSQAFQFGGV KAGPVSCLPH PGPDQSPITY
1110 1120 1130 1140 1150
CVYVYCQNKD TSKKVQMARL AWEASHPLAG NLQSSIVKFK KPLPLTQPGE
1160
NQGPGDSPQE MT
Length:1,162
Mass (Da):135,213
Last modified:May 15, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1A72CE01C1CB081C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U75698 Genomic DNA Translation: AAC57158.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75698 Genomic DNA Translation: AAC57158.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2YPYX-ray2.45A/B/C/D/E/F/G/H/I/J1013-1149[»]
2YPZX-ray3.20A/B/C/D/E/F/G/H/I/J1013-1149[»]
2YQ0X-ray3.91A996-1153[»]
SMRiQ76SB0
ModBaseiSearch...
PDBe-KBiSearch...

Family and domain databases

Gene3Di3.30.70.390, 1 hit
InterProiView protein in InterPro
IPR037007 EBNA1_DNA-bd_sf

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ76SB0_HHV8
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q76SB0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: December 11, 2019
This is version 40 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

3D-structureCombined sources
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again