Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutathione peroxidase

Gene

Gpx4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, PeroxidaseUniRule annotationSAAS annotationImported
LigandSeleniumImported

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione peroxidaseUniRule annotation
Gene namesi
Name:Gpx4Imported
Synonyms:GPx4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:104767 Gpx4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiQ76LV0
PRIDEiQ76LV0

PTM databases

SwissPalmiQ76LV0

Expressioni

Gene expression databases

BgeeiENSMUSG00000075706

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ76LV0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutathione peroxidase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1651 Eukaryota
COG0386 LUCA
HOVERGENiHBG004333
OrthoDBiEOG091G0OJG
TreeFamiTF338735

Family and domain databases

CDDicd00340 GSH_Peroxidase, 1 hit
InterProiView protein in InterPro
IPR000889 Glutathione_peroxidase
IPR029759 GPX_AS
IPR029760 GPX_CS
IPR036249 Thioredoxin-like_sf
PANTHERiPTHR11592 PTHR11592, 1 hit
PfamiView protein in Pfam
PF00255 GSHPx, 1 hit
PRINTSiPR01011 GLUTPROXDASE
SUPFAMiSSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS00460 GLUTATHIONE_PEROXID_1, 1 hit
PS00763 GLUTATHIONE_PEROXID_2, 1 hit
PS51355 GLUTATHIONE_PEROXID_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q76LV0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRAAARKRG RCRQRGGSPR GRRRRGPGRQ SPRKRPGPRR RKARARRRRR
60 70 80 90 100
ARPRRMEPIP EPFNPGPLLQ EPPQYCNSSE FLGLCASRDD WRCARSMHEF
110 120 130 140 150
SAKDIDGHMV CLDKYRGFVC IVTNVASQUG KTDVNYTQLV DLHARYAECG
160 170 180 190 200
LRILAFPCNQ FGRQEPGSNQ EIKEFAAGYN VKFDMYSKIC VNGDDAHPLW
210 220 230 240 250
KWMKVQPKGR GMLGNAIKWN FTKFLIDKNG CVVKRYGPME EPQVIEKDLP

CYL
Length:253
Mass (Da):29,194
Last modified:February 26, 2008 - v2
Checksum:iC55E2827533CDBF3
GO

Non-standard residue

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-standard residuei129SelenocysteineImported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB072797 mRNA Translation: BAC87835.1
RefSeqiNP_001032830.2, NM_001037741.3
UniGeneiMm.332810
Mm.359573

Genome annotation databases

GeneIDi625249
UCSCiuc007gbl.2 mouse

Keywords - Coding sequence diversityi

SelenocysteineImported

Similar proteinsi

Entry informationi

Entry nameiQ76LV0_MOUSE
AccessioniPrimary (citable) accession number: Q76LV0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: February 26, 2008
Last modified: June 20, 2018
This is version 120 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health