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Entry version 110 (31 Jul 2019)
Sequence version 1 (05 Jul 2004)
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Protein

BMP/retinoic acid-inducible neural-specific protein 3

Gene

BRINP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Growth arrest

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
BMP/retinoic acid-inducible neural-specific protein 3
Alternative name(s):
DBCCR1-like protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BRINP3
Synonyms:DBCCR1L, DBCCR1L1, FAM5C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:22393 BRINP3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
618390 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q76B58

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
339479

Open Targets

More...
OpenTargetsi
ENSG00000162670

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671896

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
BRINP3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74749831

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 33Sequence analysisAdd BLAST33
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000004577434 – 766BMP/retinoic acid-inducible neural-specific protein 3Add BLAST733

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi168N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi337N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi456N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi562N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi609N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi641N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q76B58

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q76B58

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q76B58

PeptideAtlas

More...
PeptideAtlasi
Q76B58

PRoteomics IDEntifications database

More...
PRIDEi
Q76B58

ProteomicsDB human proteome resource

More...
ProteomicsDBi
6410
68662 [Q76B58-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q76B58

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q76B58

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000162670 Expressed in 116 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q76B58 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q76B58 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA054693

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
130891, 20 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000356432

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q76B58

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini74 – 264MACPFAdd BLAST191

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BRINP family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IF4X Eukaryota
ENOG410XQ74 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156099

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000049122

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q76B58

Identification of Orthologs from Complete Genome Data

More...
OMAi
PNDQVAC

Database of Orthologous Groups

More...
OrthoDBi
157712at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q76B58

TreeFam database of animal gene trees

More...
TreeFami
TF331600

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033237 BRINP
IPR009030 Growth_fac_rcpt_cys_sf
IPR020864 MACPF

The PANTHER Classification System

More...
PANTHERi
PTHR15564 PTHR15564, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01823 MACPF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00457 MACPF, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57184 SSF57184, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q76B58-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MIWRSRAGAE LFSLMALWEW IALSLHCWVL AVAAVSDQHA TSPFDWLLSD
60 70 80 90 100
KGPFHRSQEY TDFVDRSRQG FSTRYKIYRE FGRWKVNNLA VERRNFLGSP
110 120 130 140 150
LPLAPEFFRN IRLLGRRPTL QQITENLIKK YGTHFLLSAT LGGEESLTIF
160 170 180 190 200
VDKRKLSKRA EGSDSTTNSS SVTLETLHQL AASYFIDRDS TLRRLHHIQI
210 220 230 240 250
ASTAIKVTET RTGPLGCSNY DNLDSVSSVL VQSPENKIQL QGLQVLLPDY
260 270 280 290 300
LQERFVQAAL SYIACNSEGE FICKENDCWC HCGPKFPECN CPSMDIQAME
310 320 330 340 350
ENLLRITETW KAYNSDFEES DEFKLFMKRL PMNYFLNTST IMHLWTMDSN
360 370 380 390 400
FQRRYEQLEN SMKQLFLKAQ KIVHKLFSLS KRCHKQPLIS LPRQRTSTYW
410 420 430 440 450
LTRIQSFLYC NENGLLGSFS EETHSCTCPN DQVVCTAFLP CTVGDASACL
460 470 480 490 500
TCAPDNRTRC GTCNTGYMLS QGLCKPEVAE STDHYIGFET DLQDLEMKYL
510 520 530 540 550
LQKTDRRIEV HAIFISNDMR LNSWFDPSWR KRMLLTLKSN KYKSSLVHMI
560 570 580 590 600
LGLSLQICLT KNSTLEPVLA VYVNPFGGSH SESWFMPVNE NSFPDWERTK
610 620 630 640 650
LDLPLQCYNW TLTLGNKWKT FFETVHIYLR SRIKSNGPNG NESIYYEPLE
660 670 680 690 700
FIDPSRNLGY MKINNIQVFG YSMHFDPEAI RDLILQLDYP YTQGSQDSAL
710 720 730 740 750
LQLLEIRDRV NKLSPPGQRR LDLFSCLLRH RLKLSTSEVV RIQSALQAFN
760
AKLPNTMDYD TTKLCS
Length:766
Mass (Da):88,445
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD325EB7E9F416FB3
GO
Isoform 2 (identifier: Q76B58-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-40: MIWRSRAGAE...AVAAVSDQHA → MPQAPSTGSS...RDLAQDTRYT
     41-142: Missing.

Note: No experimental confirmation available.
Show »
Length:664
Mass (Da):76,299
Checksum:i2A9FC9B061911025
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0J9YVN8A0A0J9YVN8_HUMAN
BMP/retinoic acid-inducible neural-...
BRINP3
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AMP1B1AMP1_HUMAN
BMP/retinoic acid-inducible neural-...
BRINP3
28Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti422E → K in AAD09521 (PubMed:16710414).Curated1
Sequence conflicti534L → F in AAD09521 (PubMed:16710414).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0555451 – 40MIWRS…SDQHA → MPQAPSTGSSLIRDPSIAHR NTQILWTEAGRDLAQDTRYT in isoform 2. 1 PublicationAdd BLAST40
Alternative sequenceiVSP_05554641 – 142Missing in isoform 2. 1 PublicationAdd BLAST102

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB111893 mRNA Translation: BAD04066.1
AK123024 mRNA Translation: BAG53853.1
AK294365 mRNA Translation: BAH11746.1
AL354771 Genomic DNA No translation available.
AL365402 Genomic DNA No translation available.
AL391645 Genomic DNA No translation available.
CH471067 Genomic DNA Translation: EAW91222.1
BC105052 mRNA Translation: AAI05053.1
BC105054 mRNA Translation: AAI05055.1
U67037 mRNA Translation: AAD09521.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1373.1 [Q76B58-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001304117.1, NM_001317188.1 [Q76B58-2]
NP_950252.1, NM_199051.2 [Q76B58-1]
XP_011507778.1, XM_011509476.2 [Q76B58-2]
XP_016856614.1, XM_017001125.1 [Q76B58-1]
XP_016856615.1, XM_017001126.1 [Q76B58-1]
XP_016856618.1, XM_017001129.1 [Q76B58-2]
XP_016856619.1, XM_017001130.1 [Q76B58-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367462; ENSP00000356432; ENSG00000162670 [Q76B58-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
339479

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:339479

UCSC genome browser

More...
UCSCi
uc001gse.2 human [Q76B58-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB111893 mRNA Translation: BAD04066.1
AK123024 mRNA Translation: BAG53853.1
AK294365 mRNA Translation: BAH11746.1
AL354771 Genomic DNA No translation available.
AL365402 Genomic DNA No translation available.
AL391645 Genomic DNA No translation available.
CH471067 Genomic DNA Translation: EAW91222.1
BC105052 mRNA Translation: AAI05053.1
BC105054 mRNA Translation: AAI05055.1
U67037 mRNA Translation: AAD09521.1
CCDSiCCDS1373.1 [Q76B58-1]
RefSeqiNP_001304117.1, NM_001317188.1 [Q76B58-2]
NP_950252.1, NM_199051.2 [Q76B58-1]
XP_011507778.1, XM_011509476.2 [Q76B58-2]
XP_016856614.1, XM_017001125.1 [Q76B58-1]
XP_016856615.1, XM_017001126.1 [Q76B58-1]
XP_016856618.1, XM_017001129.1 [Q76B58-2]
XP_016856619.1, XM_017001130.1 [Q76B58-2]

3D structure databases

SMRiQ76B58
ModBaseiSearch...

Protein-protein interaction databases

BioGridi130891, 20 interactors
STRINGi9606.ENSP00000356432

PTM databases

iPTMnetiQ76B58
PhosphoSitePlusiQ76B58

Polymorphism and mutation databases

BioMutaiBRINP3
DMDMi74749831

Proteomic databases

jPOSTiQ76B58
MaxQBiQ76B58
PaxDbiQ76B58
PeptideAtlasiQ76B58
PRIDEiQ76B58
ProteomicsDBi6410
68662 [Q76B58-1]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367462; ENSP00000356432; ENSG00000162670 [Q76B58-1]
GeneIDi339479
KEGGihsa:339479
UCSCiuc001gse.2 human [Q76B58-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
339479
DisGeNETi339479

GeneCards: human genes, protein and diseases

More...
GeneCardsi
BRINP3
HGNCiHGNC:22393 BRINP3
HPAiHPA054693
MIMi618390 gene
neXtProtiNX_Q76B58
OpenTargetsiENSG00000162670
PharmGKBiPA142671896

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IF4X Eukaryota
ENOG410XQ74 LUCA
GeneTreeiENSGT00940000156099
HOGENOMiHOG000049122
InParanoidiQ76B58
OMAiPNDQVAC
OrthoDBi157712at2759
PhylomeDBiQ76B58
TreeFamiTF331600

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
BRINP3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
339479

Protein Ontology

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PROi
PR:Q76B58

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000162670 Expressed in 116 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ76B58 baseline and differential
GenevisibleiQ76B58 HS

Family and domain databases

InterProiView protein in InterPro
IPR033237 BRINP
IPR009030 Growth_fac_rcpt_cys_sf
IPR020864 MACPF
PANTHERiPTHR15564 PTHR15564, 1 hit
PfamiView protein in Pfam
PF01823 MACPF, 1 hit
SMARTiView protein in SMART
SM00457 MACPF, 1 hit
SUPFAMiSSF57184 SSF57184, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBRNP3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q76B58
Secondary accession number(s): B3KVP1
, B7Z260, O95726, Q2M330
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: July 5, 2004
Last modified: July 31, 2019
This is version 110 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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