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UniProtKB - Q769H0 (Q769H0_HUMAN)
Protein
Alpha-helical coiled-coil rod protein
Gene
SBP 1b
Organism
Homo sapiens (Human)
Status
Functioni
May be a regulator of keratinocyte proliferation or differentiation.
ARBA annotationGO - Biological processi
- cell differentiation Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: Alpha-helical coiled-coil rod proteinARBA annotationAlternative name(s): Coiled-coil alpha-helical rod protein 1ARBA annotation |
Gene namesi | Name:SBP 1bImported Synonyms:SBPImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Keywords - Cellular componenti
CytoplasmARBA annotation, NucleusARBA annotationStructurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 62 – 82 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 177 – 218 | DisorderedSequence analysisAdd BLAST | 42 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 84 – 132 | Sequence analysisAdd BLAST | 49 | |
Coiled coili | 157 – 177 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 263 – 290 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 359 – 379 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 401 – 428 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 498 – 525 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 534 – 568 | Sequence analysisAdd BLAST | 35 | |
Coiled coili | 576 – 603 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 609 – 679 | Sequence analysisAdd BLAST | 71 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 62 – 76 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 177 – 202 | Polar residuesSequence analysisAdd BLAST | 26 | |
Compositional biasi | 203 – 218 | Basic and acidic residuesSequence analysisAdd BLAST | 16 |
Keywords - Domaini
Coiled coilSequence analysisARBA annotationPhylogenomic databases
OrthoDBi | 1046571at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR009800, HCR |
PANTHERi | PTHR46822, PTHR46822, 1 hit |
Pfami | View protein in Pfam PF07111, HCR, 1 hit |
i Sequence
Sequence statusi: Complete.
Q769H0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFPPSGSTGL IPPSHFQARP LSTLPRMAPT WLSDIPLVQP PGYQDVSERR
60 70 80 90 100
LDTQRPQVTM WERDVSSDRQ EPGRRGRSWG LEGSQALSQQ AEVIVRQLQE
110 120 130 140 150
LRRLEEEVRL LRETSLQQKM RLEAQAMELE ALARAEKAGR AEAEGLRAAL
160 170 180 190 200
AGAEVVRKNL EEGSQRELEE VQRLHQEQLS SLTQAHEEAL SSLTSKAEGL
210 220 230 240 250
EKSLSSLETR RAGEAKELAE AQREAELLRK QLSKTQEDLE AQVTLVENLR
260 270 280 290 300
KYVGEQVPSE VHSQTWELER QKLLETMQHL QEDRDSLHAT AELLQVRVQS
310 320 330 340 350
LTHILALQEE ELTRKVQPSD SLEPEFTRKC QSLLNRWREK VFALMVQLKA
360 370 380 390 400
QELEHSDSVK QLKGQVASLQ EKVTSQSQEQ AILQRSLQDK AAEVEVERMG
410 420 430 440 450
AKGLQLELSR AQEARRQWQQ QTASAEEQLR LVVNAVSSSQ IWLETTMAKV
460 470 480 490 500
EGAAAQLPSL NNRLSYAVRK VLTIRGLIAR KLALAQLRQE SCPLPPPATD
510 520 530 540 550
VSLELQQLRE ERNRLDAELQ LSARLIQQEV GRAREQGEAE RQQLSKVAQQ
560 570 580 590 600
LEQELQQTQE SLASLGLQLE VARQGQQEST EEAASLRQEL TQQQELYGQA
610 620 630 640 650
LQEKVAEVET RLREQLSDTE RRLNEARREH AKAVVSLRQI QRRAAQEKER
660 670 680 690 700
SQELRRLQEE ARKEEGQRLA RRLQELERDK NLMLATLQQE GLLSRYKQQR
710 720 730 740 750
LLTVLPSLLD KKKSVVSSPR PPECSASAPV AAAVPTRESI KGSLSVLLDD
760 770 780
LQDLSEAISK EEAVCQGDNL DRCSSSNPQM SS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB112474 mRNA Translation: BAD05130.1 AB112475 mRNA Translation: BAD05131.1 |
RefSeqi | NP_001099033.1, NM_001105563.1 NP_001099034.1, NM_001105564.1 NP_061925.2, NM_019052.3 |
Genome annotation databases
GeneIDi | 54535 |
KEGGi | hsa:54535 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB112474 mRNA Translation: BAD05130.1 AB112475 mRNA Translation: BAD05131.1 |
RefSeqi | NP_001099033.1, NM_001105563.1 NP_001099034.1, NM_001105564.1 NP_061925.2, NM_019052.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q769H0 |
Protocols and materials databases
DNASUi | 54535 |
Genome annotation databases
GeneIDi | 54535 |
KEGGi | hsa:54535 |
Organism-specific databases
CTDi | 54535 |
PharmGKBi | PA134942738 |
Phylogenomic databases
OrthoDBi | 1046571at2759 |
Miscellaneous databases
BioGRID-ORCSi | 54535, 5 hits in 1044 CRISPR screens |
GenomeRNAii | 54535 |
Family and domain databases
InterProi | View protein in InterPro IPR009800, HCR |
PANTHERi | PTHR46822, PTHR46822, 1 hit |
Pfami | View protein in Pfam PF07111, HCR, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q769H0_HUMAN | |
Accessioni | Q769H0Primary (citable) accession number: Q769H0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | January 19, 2022 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |