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Entry version 107 (07 Oct 2020)
Sequence version 1 (05 Jul 2004)
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Protein

GTPase IMAP family member 8

Gene

Gimap8

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei76GTPBy similarity1
Binding sitei209GTPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi55 – 63GTPBy similarity9
Nucleotide bindingi173 – 175GTPBy similarity3

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandGTP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
GTPase IMAP family member 8
Short name:
mGIMAP8
Alternative name(s):
Immune-associated nucleotide-binding protein 9
Short name:
IAN-9
Immunity-associated protein 8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Gimap8
Synonyms:Ian91 Publication, Imap8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685303, Gimap8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003419711 – 688GTPase IMAP family member 8Add BLAST688

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q75N62

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q75N62

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q75N62

PRoteomics IDEntifications database

More...
PRIDEi
Q75N62

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q75N62

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q75N62

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Abundantly expressed in the thymus (in thymocytes), spleen (in splenocytes), lymph node, followed by bone marrow and lung.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000064262, Expressed in mesenteric lymph node and 183 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q75N62, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q75N62, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q75N62, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000077350

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q75N62, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q75N62

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini46 – 247AIG1-type G 1PROSITE-ProRule annotationAdd BLAST202
Domaini282 – 472AIG1-type G 2PROSITE-ProRule annotationAdd BLAST191
Domaini473 – 677AIG1-type G 3PROSITE-ProRule annotationAdd BLAST205

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni55 – 62G1PROSITE-ProRule annotation8
Regioni82 – 86G2PROSITE-ProRule annotation5
Regioni103 – 106G3PROSITE-ProRule annotation4
Regioni172 – 175G4PROSITE-ProRule annotation4
Regioni208 – 210G5PROSITE-ProRule annotation3

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RB0C, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162462

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010468_5_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q75N62

Identification of Orthologs from Complete Genome Data

More...
OMAi
QHCLELS

Database of Orthologous Groups

More...
OrthoDBi
1033397at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q75N62

TreeFam database of animal gene trees

More...
TreeFami
TF330845

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006703, G_AIG1
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04548, AIG1, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51720, G_AIG1, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q75N62-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATSSHQGAA AGSQAEHRSC EASVGQGERP SASQGQEGNF KQNQGTSTLR
60 70 80 90 100
LLLLGKQGAG KSATGNTILG KAVFESKFSD HMVTDRCQSE SVSVRGKQVI
110 120 130 140 150
VIDTPDLFSS LSCSEVRQQN LKQCLELLAD DHCVLLLVTP IGHYTEEDRE
160 170 180 190 200
TIEGIWGKIG PKAYRHMIVV FTREDELDED SLWNYIESKE SLKELIKNIG
210 220 230 240 250
SRRCCTFNNK ADKKQRELQV FKLLDAIELL MMESPEPYFE PLKMESSGVQ
260 270 280 290 300
GCGNGVTYEG DTLCGSKKRQ PQITGPDCDP DMPELRVLLM GKRGVGKSAA
310 320 330 340 350
GNSILGKQVF KTQFSEKQRV TKAFASHSRV WQGKKVLIID SPEISSWKLD
360 370 380 390 400
ESAVKNHTFP GPHAFLLVTP LGSSLKSDDD VFSIIKRIFG EKFTKFTIVL
410 420 430 440 450
FTRKEDFEDQ ALDKVIKEND ALYNLTQKFG ERYAIFNYRA SVEEEQSQVG
460 470 480 490 500
KLLSQIEKMV QCHSNKPCVI REKELLNIIL LGRSGAGKSA TGNTILGRSA
510 520 530 540 550
FFSQLRAQPV TSSSQSGKRT LDWQDVVVVD TPSFIQTPGT EKDPSRLKEE
560 570 580 590 600
IHHCLSLCEE GMKIFVLVLQ LGRFTQEDEV VVEQLEASFE ENIMKYMIVL
610 620 630 640 650
FTRKEDLGDG DLHDYTNNTK NKALKKILKK CNGRVCAFNN KETGEDQETQ
660 670 680
VKGLLKIANS LKKNYDEHSN SWVGQLKSTL GQITMAFK
Length:688
Mass (Da):76,843
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8B20E5ED1336DC08
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R3P9C7A0A0R3P9C7_MOUSE
GTPase IMAP family member 8
Gimap8
349Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti204C → Y in BAE22049 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ617674 mRNA Translation: CAE85147.1
AB178029 mRNA Translation: BAD16741.1
AK134199 mRNA Translation: BAE22049.1
BC137943 mRNA Translation: AAI37944.1
BC137944 mRNA Translation: AAI37945.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS20108.1

NCBI Reference Sequences

More...
RefSeqi
NP_001070878.1, NM_001077410.1
NP_997651.1, NM_212486.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000203083; ENSMUSP00000145286; ENSMUSG00000064262
ENSMUST00000203509; ENSMUSP00000145255; ENSMUSG00000064262

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
243374

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:243374

UCSC genome browser

More...
UCSCi
uc009bvf.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ617674 mRNA Translation: CAE85147.1
AB178029 mRNA Translation: BAD16741.1
AK134199 mRNA Translation: BAE22049.1
BC137943 mRNA Translation: AAI37944.1
BC137944 mRNA Translation: AAI37945.1
CCDSiCCDS20108.1
RefSeqiNP_001070878.1, NM_001077410.1
NP_997651.1, NM_212486.2

3D structure databases

SMRiQ75N62
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ75N62, 1 interactor
STRINGi10090.ENSMUSP00000077350

PTM databases

iPTMnetiQ75N62
PhosphoSitePlusiQ75N62

Proteomic databases

EPDiQ75N62
MaxQBiQ75N62
PaxDbiQ75N62
PRIDEiQ75N62

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2915, 125 antibodies

Genome annotation databases

EnsembliENSMUST00000203083; ENSMUSP00000145286; ENSMUSG00000064262
ENSMUST00000203509; ENSMUSP00000145255; ENSMUSG00000064262
GeneIDi243374
KEGGimmu:243374
UCSCiuc009bvf.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
155038
MGIiMGI:2685303, Gimap8

Phylogenomic databases

eggNOGiENOG502RB0C, Eukaryota
GeneTreeiENSGT00940000162462
HOGENOMiCLU_010468_5_1_1
InParanoidiQ75N62
OMAiQHCLELS
OrthoDBi1033397at2759
PhylomeDBiQ75N62
TreeFamiTF330845

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
243374, 1 hit in 18 CRISPR screens

Protein Ontology

More...
PROi
PR:Q75N62
RNActiQ75N62, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000064262, Expressed in mesenteric lymph node and 183 other tissues
ExpressionAtlasiQ75N62, baseline and differential
GenevisibleiQ75N62, MM

Family and domain databases

InterProiView protein in InterPro
IPR006703, G_AIG1
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF04548, AIG1, 3 hits
SUPFAMiSSF52540, SSF52540, 3 hits
PROSITEiView protein in PROSITE
PS51720, G_AIG1, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGIMA8_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q75N62
Secondary accession number(s): Q3UZ12
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 5, 2004
Last modified: October 7, 2020
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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