Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 96 (08 May 2019)
Sequence version 2 (05 Oct 2010)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

ABR043Wp

Gene

AGOS_ABR043W

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ABR043WpImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:AGOS_ABR043WImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284811 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000591 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 36HelicalSequence analysisAdd BLAST25
Transmembranei57 – 78HelicalSequence analysisAdd BLAST22
Transmembranei90 – 108HelicalSequence analysisAdd BLAST19
Transmembranei134 – 159HelicalSequence analysisAdd BLAST26
Transmembranei165 – 183HelicalSequence analysisAdd BLAST19
Transmembranei195 – 213HelicalSequence analysisAdd BLAST19
Transmembranei256 – 276HelicalSequence analysisAdd BLAST21
Transmembranei288 – 319HelicalSequence analysisAdd BLAST32
Transmembranei355 – 381HelicalSequence analysisAdd BLAST27
Transmembranei402 – 422HelicalSequence analysisAdd BLAST21
Transmembranei428 – 449HelicalSequence analysisAdd BLAST22
Transmembranei456 – 480HelicalSequence analysisAdd BLAST25
Transmembranei500 – 518HelicalSequence analysisAdd BLAST19
Transmembranei598 – 617HelicalSequence analysisAdd BLAST20
Transmembranei629 – 654HelicalSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
33169.AAS50813

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000106394

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q75DI2

KEGG Orthology (KO)

More...
KOi
K20989

Identification of Orthologs from Complete Genome Data

More...
OMAi
WALKRYQ

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1730.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031155 DUR
IPR038377 Na/Glc_symporter_sf
IPR001734 Na/solute_symporter

The PANTHER Classification System

More...
PANTHERi
PTHR46154:SF4 PTHR46154:SF4, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00474 SSF, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00813 sss, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50283 NA_SOLUT_SYMP_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q75DI2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDHLNPPLSQ GVGYAIVVGL GAVFAIGMVM TTYILRRYQR EVITAEEFAT
60 70 80 90 100
AGRTVKTGLI ASAVVSSWTW AATLLQSTTM AYKVGVSGPF YYAAGACVQI
110 120 130 140 150
ILFSTLAIKC KQRAPNAHTF LEIIKARYGR KAHILHMCYA LVTNVLVTTM
160 170 180 190 200
LLTGGSAVVS ELTGMHTAAA CFLLPVGVII YTLFGGIKAT FLTDYVHTVI
210 220 230 240 250
IVGIILTFTF SVYRTSDMLG SASKVYDLLR EAARQHPVKG NRNGEYLTMK
260 270 280 290 300
SESGGIFFVV SLVGNFGTVL LDNGYFTKAF SSSPAAALPG YVVGGIVWFA
310 320 330 340 350
IPCLVATSLG LACLALELLP SFPNYPSRLS QEQVDAGLVL PVAAFNLLGK
360 370 380 390 400
GGAMAALLMV FMAVTSAMSA ELIAVSTIFT YDIYRGYVNP DAPGKRLIVT
410 420 430 440 450
SHAACVVFGV AMSAVSVGLY YAGISLGYLY EVMGIIISSA VIPSALTLFW
460 470 480 490 500
SKQNIYAVTI APLVGTTLAV TSWLVCAKVL YGSITVENTY KDYPMLTGNL
510 520 530 540 550
VALLSPALLI PLLTYSLGAD SYDWIAMKTD ILRVDETDEL LDADKGLAMV
560 570 580 590 600
VTRELFESSS VPSAIEKEEI NHTTEPNLQR EMTNGLEEER ILKRASRLAT
610 620 630 640 650
ILCAIFILSF LVLWPVPMYG TGYIFSKGFF TGWVSVLTLW LFCTGFAVCI
660 670 680
YPLWEGRHGL FTTVRGIYWD CTGQKAKLRD WQCSQI
Length:686
Mass (Da):74,364
Last modified:October 5, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE43D9F43BB99FE5D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE016815 Genomic DNA Translation: AAS50813.2

NCBI Reference Sequences

More...
RefSeqi
NP_982989.2, NM_208342.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
AAS50813; AAS50813; AGOS_ABR043W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4619086

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ago:AGOS_ABR043W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016815 Genomic DNA Translation: AAS50813.2
RefSeqiNP_982989.2, NM_208342.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi33169.AAS50813

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiAAS50813; AAS50813; AGOS_ABR043W
GeneIDi4619086
KEGGiago:AGOS_ABR043W

Phylogenomic databases

HOGENOMiHOG000106394
InParanoidiQ75DI2
KOiK20989
OMAiWALKRYQ

Family and domain databases

Gene3Di1.20.1730.10, 1 hit
InterProiView protein in InterPro
IPR031155 DUR
IPR038377 Na/Glc_symporter_sf
IPR001734 Na/solute_symporter
PANTHERiPTHR46154:SF4 PTHR46154:SF4, 1 hit
PfamiView protein in Pfam
PF00474 SSF, 1 hit
TIGRFAMsiTIGR00813 sss, 1 hit
PROSITEiView protein in PROSITE
PS50283 NA_SOLUT_SYMP_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ75DI2_ASHGO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q75DI2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: October 5, 2010
Last modified: May 8, 2019
This is version 96 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again