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Protein

Mitochondrial import inner membrane translocase subunit TIM44

Gene

AGOS_ADL118C

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.UniRule annotation

GO - Molecular functioni

  • chaperone binding Source: GO_Central
  • protein binding, bridging Source: EnsemblFungi

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import inner membrane translocase subunit TIM44UniRule annotation
Gene namesi
ORF Names:AGOS_ADL118CImported
OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)Imported
Taxonomic identifieri284811 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
Proteomesi
  • UP000000591 Componenti: Chromosome IV

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi33169.AAS51802

Structurei

3D structure databases

ProteinModelPortaliQ75AP0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini257 – 411Tim44InterPro annotationAdd BLAST155

Sequence similaritiesi

Belongs to the Tim44 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000208172
InParanoidiQ75AP0
KOiK17804
OMAiRFLKQCE
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit

Sequencei

Sequence statusi: Complete.

Q75AP0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHRYSAVKQA QKSQPQRVLA ARGFSATRWA GNGPKSPLQV FRETFKEEWK
60 70 80 90 100
KSQELQDNIK ALQDAGGRLG ESDAYKKARE AYLKAQKGST IVGKTLKRTG
110 120 130 140 150
ETLEHITVQA WESEIGKTTR KTVSKTAQKL DESFEPVRQT KVYKDMSEII
160 170 180 190 200
DDGESSRYGG FMEKERRREK RERDLATGKR ATPVRSNEEA GSALVATDKE
210 220 230 240 250
ASESLGKKIQ DFKEKTVVGR KLHEIKVRLW DENENPLIGL LRTISNKVGG
260 270 280 290 300
LFAETESARV FAQFKLLDPT FNTEEFTKHL REYIIPEVLE AYVKGDEQVL
310 320 330 340 350
KQWFSEAPYN VYSAQQKQIR QQELFADGRI LDIRGVEIIS AKLLPPQDVP
360 370 380 390 400
AIVVGCRAQE IHLFRKATTG EIAAGHESNI MLSSYAMVLT RDPEKVDDKE
410
TEGWKILEFV RGGSRSFT
Length:418
Mass (Da):47,403
Last modified:July 5, 2004 - v1
Checksum:i87EDD59B2BB6E284
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016817 Genomic DNA Translation: AAS51802.1
RefSeqiNP_983978.1, NM_209331.2

Genome annotation databases

EnsemblFungiiAAS51802; AAS51802; AGOS_ADL118C
GeneIDi4620121
KEGGiago:AGOS_ADL118C

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016817 Genomic DNA Translation: AAS51802.1
RefSeqiNP_983978.1, NM_209331.2

3D structure databases

ProteinModelPortaliQ75AP0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi33169.AAS51802

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiAAS51802; AAS51802; AGOS_ADL118C
GeneIDi4620121
KEGGiago:AGOS_ADL118C

Phylogenomic databases

HOGENOMiHOG000208172
InParanoidiQ75AP0
KOiK17804
OMAiRFLKQCE
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ75AP0_ASHGO
AccessioniPrimary (citable) accession number: Q75AP0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 7, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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