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Entry version 104 (16 Oct 2019)
Sequence version 2 (09 Jan 2013)
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Protein

Probable E3 ubiquitin-protein ligase TOM1

Gene

TOM1

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable ubiquitin ligase protein, which may be involved in mRNA export. E3 ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. Participates in mRNA export from the nucleus by regulating the transport of hnRNP proteins.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.26

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei3225Glycyl thioester intermediatePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processmRNA transport, Transport, Ubl conjugation pathway

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable E3 ubiquitin-protein ligase TOM1 (EC:2.3.2.26)
Alternative name(s):
HECT-type E3 ubiquitin transferase TOM1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TOM1
Ordered Locus Names:AER304C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284811 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000591 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome V

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001203451 – 3258Probable E3 ubiquitin-protein ligase TOM1Add BLAST3258

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q756G2

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
33169.AAS52985

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q756G2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2922 – 3258HECTPROSITE-ProRule annotationAdd BLAST337

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1883 – 1957Asp-richAdd BLAST75

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPL family. TOM1/PTR1 subfamily.Curated

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000093627

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q756G2

KEGG Orthology (KO)

More...
KOi
K10592

Identification of Orthologs from Complete Genome Data

More...
OMAi
HGLLFQI

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00078 HECTc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR010309 E3_Ub_ligase_DUF908
IPR010314 E3_Ub_ligase_DUF913
IPR000569 HECT_dom
IPR035983 Hect_E3_ubiquitin_ligase
IPR025527 HUWE1/Rev1_UBM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06012 DUF908, 1 hit
PF06025 DUF913, 1 hit
PF00632 HECT, 1 hit
PF14377 UBM, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00119 HECTc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF56204 SSF56204, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50237 HECT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q756G2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVVTLTKLER LQKAEKSRTF KPLIDELINC EDAVFVGKLE AIREWDRPKD
60 70 80 90 100
DLFLWIPVLD RMDDMLGKVV AKYKYHTTDC KRHPVKLIEM AKPDEDWVAT
110 120 130 140 150
LLFFTCRLLN NTSNRSLYSS LDMMSDLLNC PNFRVKLGAM KVIATIGERH
160 170 180 190 200
VVARHRIENS SVLASQHLKK RSLSLALALP SSTTDDNSDH FSLVDLFFDK
210 220 230 240 250
RKYPSKWSQL QYTYYITKKQ AGQQSTQKPS QVSSMKRFVL NNEELRFLSL
260 270 280 290 300
QQIFDRAMND LPSEFWFDFS LQASIAKAFS DDSFENIQLR SLIIQTKFAA
310 320 330 340 350
IAFANAIYIP PQVSSKLFEM DPYAFNNLTD FISLSETKIP KDLRTDALFA
360 370 380 390 400
LECISLKHVW CSDIVRNLGG NMSHGLLFQI LRYIAKVLRE GDEDAVDEEY
410 420 430 440 450
NVRFFYLISN LADVKALQES LISAGLISSL LEIVSTQNSK YKRTLASAAH
460 470 480 490 500
LLEDVISDAD ATAEFINNNG FNILIQTVTY EVNFAVQNPS SAEPPKYSVV
510 520 530 540 550
YYSISFRQLG FIRSLLKLVL KLLKTDSGDR IRNLIDSPIL LAFNKILENR
560 570 580 590 600
PVFGYTLVSH ALDVVQTIIN TEPTIYQVLV ESGTIPYILQ NFDQFLGPTS
610 620 630 640 650
DLLCMLPEVI SAICLNTDGL KQVKEKNLLK YLFQVIKTPE FAKILSWEDQ
660 670 680 690 700
AVNYGVALDE LARHYPELKP LIEDYFAATV KELPSLTSYT HSYLYESTAG
710 720 730 740 750
NGEFYLSENE TIIDNEDGAD ELAFWEVQES SPIIDCFSGV FYSMASENIS
760 770 780 790 800
WANLTEKIAF QDFLSVAIPE KPTFDYINSQ TLLNFTDVLK MFDDERRSYA
810 820 830 840 850
LPELLTILDS KFADLEDFLS YDFTKSYVLN EPKDRVVATL NKLNVLNVIL
860 870 880 890 900
YIMTDIYINI TTLFPVRVIQ MMEFFEKNGF NLITNLRKMF QRCVLEEMYI
910 920 930 940 950
RSRLPPAVAE ETISPGISFV PPILIHKDVP LKTEAKQEKT SAKFKNTLET
960 970 980 990 1000
RHLFQKVQSW TSMLFRCFLR LTHARKMNVE RYDRALEIRI FDKVVNEIVE
1010 1020 1030 1040 1050
MLNLDYLDSH LSYFLVVLDF NTHIFTCPKA SLTISDGIVQ TVPTFLFYQA
1060 1070 1080 1090 1100
GGFAIYHELI KKLSTRLLGF DGIEAIEKVE YVKDQDDILT VGVLMNSIAF
1110 1120 1130 1140 1150
MNRCIQLETM ENIRSIAEYY PYDDIYYNLT RALIVPVKIL SLGAISEIFS
1160 1170 1180 1190 1200
QGEVFDTDRR RIPYSVFKQI LSLLKNIYNS TFELEEGTDV YELRWDLMPI
1210 1220 1230 1240 1250
SHRKVEMLKS CGISHDVAVG YLEEEKDELP IHVKPDVFSD SEWQRYQEER
1260 1270 1280 1290 1300
SSGSWRTNIE LLPPQYNGSS TRETLSKMRT EFYQNGFESG ILKILQHYPK
1310 1320 1330 1340 1350
LINAISHMFF EMYGELGFSH TTMLEDLQDM MNTIPIENTN KLAPVIHLFG
1360 1370 1380 1390 1400
IFLNDKNIYD QAKKEIFKFV SYLSMNLHPE NVNYSWFSKA LYVYEIIFAK
1410 1420 1430 1440 1450
SETPEASPLP ENVTVSFSSI PIIYRISQKD KDIIFNLLIR ANEVTDFYSA
1460 1470 1480 1490 1500
LAISRILILY TREERYAQEV TQSGILSKLL KVIGANQKFD KINYLESSYL
1510 1520 1530 1540 1550
LLVRRCFETK EIVTSLIDYE LTRAFTTRAI GDHKEKPRDL PALVNEKASI
1560 1570 1580 1590 1600
VMRDPEVFVN RISETARFED FNSSKELASL SVRRHMDEKD EEMTSKPLSS
1610 1620 1630 1640 1650
EGSNSPITGI VHLLLSQLMA AHKRDWVSET PLTPEEENQK NKKKKDEVKV
1660 1670 1680 1690 1700
SKNPVCAYMI FLLKVLTELV SSYKQSKFEF LTYNKKNVYN ETPKPRATAL
1710 1720 1730 1740 1750
NFFLYQLLDT NFQDMDKHEG KRRAMISGLA RDTIIGFVSS VQDSETKKVD
1760 1770 1780 1790 1800
PKIVDSDMTY IRKFTIEAIS KAIKEAGVSA KTIDANAGKL FGWFHLISSL
1810 1820 1830 1840 1850
LVVDKGYIFS VLDSNKSSND KYQLCKLLIE MNTPGTITDC MASLDLNYPL
1860 1870 1880 1890 1900
TKKLFNSAVE PLNALNEVRN NFADLFKLEN NEDEDVEDVE SDKDDVPDMF
1910 1920 1930 1940 1950
KNSALGMYDI EDVEDDHDDD ENESLIGDDE DIAFVHDEDG LEVVFSEDED
1960 1970 1980 1990 2000
ANEDTTDASN SIGSDSEGNS DFGGSGPNVT LEVYTDSEDA IEDVNTAAIR
2010 2020 2030 2040 2050
ITSGNSAEHS YYSEGEDSAE IEIYEEEYDS EIDIDMDDDS ELGSSNWESG
2060 2070 2080 2090 2100
LSDLSDSEAY SDEERTNNTG DGFVRWYSDD GVEFEDDTDE EGRGLFTGIQ
2110 2120 2130 2140 2150
HVFPTEEQLF RVHASGAARS TGRHHHRHGA APFTTSTITL GASQRRPHSI
2160 2170 2180 2190 2200
LSNPLGPSGL EEVENDIVSH YLGNVETSDR IGLSSIPRLP RVLLFDGELF
2210 2220 2230 2240 2250
DDKSSSGILL KSTTARWNDI YEMFYDSKVY SNNVVTTIIS RIFEPSAELY
2260 2270 2280 2290 2300
LKEQEENAVK ESSRINEPTR RQDERKRKLH EIDSDEEHIE EEEEHDEVVE
2310 2320 2330 2340 2350
PIEAPGINSP QARAPQEPVY VTIDGEAVNI AGTDMDAEFL NALPDDIRAE
2360 2370 2380 2390 2400
VFAQHIREYR TQFQGSEGSS RELDAGFLNT IPETLRQEIL AQEVPLERNA
2410 2420 2430 2440 2450
RPSILGLRNR EGEEFSEVED ESPRFNEQRT ESSKTKTDRV HFAPLLDRSG
2460 2470 2480 2490 2500
IAAIMKAVFI PQPYLSREIY HELFYRLCSS KQNRSDIMNM LLLILMDGIN
2510 2520 2530 2540 2550
DQHSLERVYN LLSNRAASSN SGTSKTPQRQ LPPDCTPLIV TNQCIEILQS
2560 2570 2580 2590 2600
MVDADSKLKY FFITEHENLL INKSPLKNKK DIFSKNMKWP INCILALLEK
2610 2620 2630 2640 2650
KVITDEAVLM DLLTRILQVC SKPISSIVKS SKDGKKKKFE VPDIEKKYLA
2660 2670 2680 2690 2700
SIVSIIKLDS CNTKVFQQTL NLMTNLFAIK DAHETFTTEL CNLAKETIEV
2710 2720 2730 2740 2750
LVTDLDALAK EVPAVDSGTE VSSEIIQKFT VPSSDQSKLL KVLTAIDYIY
2760 2770 2780 2790 2800
VNRKKEEEQV VDQLLPLYNK MELGHIWVSL SNCLTRFEEK PRMSTSATIL
2810 2820 2830 2840 2850
LPLIESLMVV CKHSKVRETK DALLKYEAKK CDFARTPVEN LFFAFTDLHK
2860 2870 2880 2890 2900
KLLNEMIRSN PKLMSGPFSL LVKNPKILDF DNKRYYFTAQ LRAITHDRPK
2910 2920 2930 2940 2950
LSISVRREHV FLDSYRSLFF KSNEDIKISK LEISFKGEAG VDAGGITREW
2960 2970 2980 2990 3000
YQVLSRQMFN PDYALFIPVA SDKTTFRPNR TSGINPEHLS FFKFIGMIIG
3010 3020 3030 3040 3050
KAISDQCFLD CHFSREVYKN ILGKPVALKD MESLDLDYYK SLIWILENDI
3060 3070 3080 3090 3100
TDIIEETFSV ETDDYGEHKV IELIENGAHV AVTEQNKHDY VKKIVEYKLQ
3110 3120 3130 3140 3150
TSVKDQMENF LQGFYAIIPK DLISIFDEQE LELLVSGLPD IDVDDWKNNT
3160 3170 3180 3190 3200
IYVNYTPTCK QINYFWRAVR SFDKEERAKL LQFVTGTSKV PLNGFKELSG
3210 3220 3230 3240 3250
VNGISKFSIH RDYGSIDRLP SSHTCFNQLD LPAYDSYETL RGSLLLAINE

GHEGFGIA
Length:3,258
Mass (Da):372,401
Last modified:January 9, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0751CA476D9646A2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE016818 Genomic DNA Translation: AAS52985.2

NCBI Reference Sequences

More...
RefSeqi
NP_985161.2, NM_210515.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
AAS52985; AAS52985; AGOS_AER304C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4621374

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ago:AGOS_AER304C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016818 Genomic DNA Translation: AAS52985.2
RefSeqiNP_985161.2, NM_210515.2

3D structure databases

SMRiQ756G2
ModBaseiSearch...

Protein-protein interaction databases

STRINGi33169.AAS52985

Proteomic databases

PRIDEiQ756G2

Genome annotation databases

EnsemblFungiiAAS52985; AAS52985; AGOS_AER304C
GeneIDi4621374
KEGGiago:AGOS_AER304C

Phylogenomic databases

HOGENOMiHOG000093627
InParanoidiQ756G2
KOiK10592
OMAiHGLLFQI

Enzyme and pathway databases

UniPathwayiUPA00143

Family and domain databases

CDDicd00078 HECTc, 1 hit
Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR010309 E3_Ub_ligase_DUF908
IPR010314 E3_Ub_ligase_DUF913
IPR000569 HECT_dom
IPR035983 Hect_E3_ubiquitin_ligase
IPR025527 HUWE1/Rev1_UBM
PfamiView protein in Pfam
PF06012 DUF908, 1 hit
PF06025 DUF913, 1 hit
PF00632 HECT, 1 hit
PF14377 UBM, 2 hits
SMARTiView protein in SMART
SM00119 HECTc, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF56204 SSF56204, 1 hit
PROSITEiView protein in PROSITE
PS50237 HECT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTOM1_ASHGO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q756G2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 9, 2013
Last modified: October 16, 2019
This is version 104 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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