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UniProtKB - Q755H8 (RBD2_ASHGO)
Protein
Rhomboid protein 2
Gene
RBD2
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Functioni
Probable serine protease.
By similaritySites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 124 | NucleophileBy similarity | 1 | |
Active sitei | 177 | By similarity | 1 |
GO - Molecular functioni
- serine-type endopeptidase activity Source: GO_Central
Keywordsi
Molecular function | Hydrolase, Protease, Serine protease |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:RBD2 Ordered Locus Names:AFL155C |
Organismi | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
Taxonomic identifieri | 284811 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium › |
Proteomesi |
|
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Multi-pass membrane protein By similarity
- cis-Golgi network membrane By similarity; Multi-pass membrane protein By similarity
Golgi apparatus
- Golgi membrane Source: UniProtKB-SubCell
Nucleus
- nuclear periphery Source: EnsemblFungi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 17 – 37 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 58 – 78 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 94 – 114 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 116 – 136 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 155 – 175 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000206182 | 1 – 261 | Rhomboid protein 2Add BLAST | 261 |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the peptidase S54 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2632, Eukaryota |
HOGENOMi | CLU_071084_0_0_1 |
InParanoidi | Q755H8 |
OMAi | TFPLIHL |
Family and domain databases
Gene3Di | 1.20.1540.10, 1 hit |
InterProi | View protein in InterPro IPR022764, Peptidase_S54_rhomboid_dom IPR035952, Rhomboid-like_sf |
Pfami | View protein in Pfam PF01694, Rhomboid, 1 hit |
SUPFAMi | SSF144091, SSF144091, 1 hit |
i Sequence
Sequence statusi: Complete.
Q755H8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDWKSMLRTG VHKPGALTAG LSVFLTLVYV LNWVFPINEK ILLDPGALRK
60 70 80 90 100
LQLTRLSLYP LAHLSIFHLL LNLMSLFVPL SMFEASHGTV FTGITLNLLA
110 120 130 140 150
IVTGVVYCLV GMLLYPNVYV GGASGWCFTL CGYFAVQEAG FRPHYELASL
160 170 180 190 200
KMPTLYIPLV FLVLVTLLMP GSSFVGHLIG LGLGYLIGFR ERWLQMATPP
210 220 230 240 250
GWLIVKIETW LDRWISMIPS VVKYHRESSV DRTAGYTPLY QESELPLHND
260
NFPGQGRVLG P
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE016819 Genomic DNA Translation: AAS53219.1 |
RefSeqi | NP_985395.1, NM_210749.1 |
Genome annotation databases
EnsemblFungii | AAS53219; AAS53219; AGOS_AFL155C |
GeneIDi | 4621621 |
KEGGi | ago:AGOS_AFL155C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE016819 Genomic DNA Translation: AAS53219.1 |
RefSeqi | NP_985395.1, NM_210749.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 33169.AAS53219 |
Genome annotation databases
EnsemblFungii | AAS53219; AAS53219; AGOS_AFL155C |
GeneIDi | 4621621 |
KEGGi | ago:AGOS_AFL155C |
Phylogenomic databases
eggNOGi | KOG2632, Eukaryota |
HOGENOMi | CLU_071084_0_0_1 |
InParanoidi | Q755H8 |
OMAi | TFPLIHL |
Family and domain databases
Gene3Di | 1.20.1540.10, 1 hit |
InterProi | View protein in InterPro IPR022764, Peptidase_S54_rhomboid_dom IPR035952, Rhomboid-like_sf |
Pfami | View protein in Pfam PF01694, Rhomboid, 1 hit |
SUPFAMi | SSF144091, SSF144091, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RBD2_ASHGO | |
Accessioni | Q755H8Primary (citable) accession number: Q755H8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 8, 2005 |
Last sequence update: | July 5, 2004 | |
Last modified: | September 29, 2021 | |
This is version 97 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Peptidase families
Classification of peptidase families and list of entries - SIMILARITY comments
Index of protein domains and families