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Protein

ADIPOR-like receptor IZH1

Gene

IZH1

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

ADIPOR-like receptor involved in zinc metabolism either by altering membrane sterol content or by directly altering cellular zinc levels.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
ADIPOR-like receptor IZH1
Gene namesi
Name:IZH1
Ordered Locus Names:AFR337W
OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Taxonomic identifieri284811 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
Proteomesi
  • UP000000591 Componenti: Chromosome VI

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 80LumenalBy similarityAdd BLAST80
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Topological domaini102 – 113CytoplasmicBy similarityAdd BLAST12
Transmembranei114 – 136HelicalSequence analysisAdd BLAST23
Topological domaini137 – 148LumenalBy similarityAdd BLAST12
Transmembranei149 – 169HelicalSequence analysisAdd BLAST21
Topological domaini170 – 175CytoplasmicBy similarity6
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Topological domaini197 – 210LumenalBy similarityAdd BLAST14
Transmembranei211 – 231HelicalSequence analysisAdd BLAST21
Topological domaini232 – 243CytoplasmicBy similarityAdd BLAST12
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Topological domaini265 – 283LumenalBy similarityAdd BLAST19
Transmembranei284 – 304HelicalSequence analysisAdd BLAST21
Topological domaini305 – 317CytoplasmicBy similarityAdd BLAST13

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002403721 – 317ADIPOR-like receptor IZH1Add BLAST317

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi73N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi197N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi33169.AAS53708

Structurei

3D structure databases

SMRiQ753H5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ADIPOR family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000197115
InParanoidiQ753H5
KOiK07297
OMAiMAWMATS
OrthoDBiEOG092C3SK7

Family and domain databases

InterProiView protein in InterPro
IPR004254 AdipoR/HlyIII-related
PANTHERiPTHR20855 PTHR20855, 1 hit
PfamiView protein in Pfam
PF03006 HlyIII, 1 hit

Sequencei

Sequence statusi: Complete.

Q753H5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEERGMKEQ TISEMAQEMA HTTSEGLKKR IRKLYTFDEL PAWQKDNELI
60 70 80 90 100
LSGYVRETNS VKECLRAMTY FNNESINIYT HLIPGVAYLV LFLIFADLVL
110 120 130 140 150
AQLLPGLDAG EHRMLRFYLL GAFTCLACSS CFHCLKQHSE PHSRLWSKVD
160 170 180 190 200
YLGILAQITC STISLLYYGY HSYPSHFVFF STLTVALCSA CAVLVLNDSF
210 220 230 240 250
NTVAFRPLRA FLFMAFGLSG VIPVLAGSYQ FGFAEWAARI QLKYVLYEAV
260 270 280 290 300
FYITGALVYG FRIPERFAPG KFDMVGHSHQ IFHLLVVLGT LCHFRAVTGS
310
YIFICTGKHY SSLLMFI
Length:317
Mass (Da):35,981
Last modified:July 5, 2004 - v1
Checksum:iA1EA7C9636B710E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016819 Genomic DNA Translation: AAS53708.1
RefSeqiNP_985884.1, NM_211239.1

Genome annotation databases

EnsemblFungiiAAS53708; AAS53708; AGOS_AFR337W
GeneIDi4622151
KEGGiago:AGOS_AFR337W

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016819 Genomic DNA Translation: AAS53708.1
RefSeqiNP_985884.1, NM_211239.1

3D structure databases

SMRiQ753H5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi33169.AAS53708

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiAAS53708; AAS53708; AGOS_AFR337W
GeneIDi4622151
KEGGiago:AGOS_AFR337W

Phylogenomic databases

HOGENOMiHOG000197115
InParanoidiQ753H5
KOiK07297
OMAiMAWMATS
OrthoDBiEOG092C3SK7

Family and domain databases

InterProiView protein in InterPro
IPR004254 AdipoR/HlyIII-related
PANTHERiPTHR20855 PTHR20855, 1 hit
PfamiView protein in Pfam
PF03006 HlyIII, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiIZH1_ASHGO
AccessioniPrimary (citable) accession number: Q753H5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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